Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Paul H. Wiedenau"'
Publikováno v:
Organic Process Research & Development. 18:699-708
A practical and scalable route to the SMO antagonist SEN826 1 is described herein, including the discussion of an alternative approach to the synthesis of the target molecule. The optimized route consists of five chemical steps. A new and efficient a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d348b1c5f978bdd85c3fef7d3001d680
https://doi.org/10.1021/op4002092
https://doi.org/10.1021/op4002092
Publikováno v:
Organic Process Research & Development. 17:1042-1051
A practical and scalable route to the Wnt inhibitor SEN461 1 is described herein. The optimized route consists of nine chemical steps. The intermediates are solids and were isolated by filtrations....
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30f8997dd4291ab0492843fdf452158d
https://doi.org/10.1021/op400145w
https://doi.org/10.1021/op400145w
Autor:
Matteo Betti, Salvatore Sanna Coccone, Paul H. Wiedenau, Giulio Castagnoli, Alessandro Panico
Publikováno v:
Organic Process Research & Development. 16:1739-1745
A practical and scalable route to the SMO receptor antagonist SEN794 1 is described herein. A new and efficient access to the key intermediate 7 via the Krohnke reaction was developed, significantl...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af8934033e3efa1cfdf71aadb9730dd9
https://doi.org/10.1021/op300170q
https://doi.org/10.1021/op300170q