Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Paul H. Weigel"'
Autor:
Wenbin Wei, Jessica L. Faubel, Hemaa Selvakumar, Daniel T. Kovari, Joanna Tsao, Felipe Rivas, Amar T. Mohabir, Michelle Krecker, Elaheh Rahbar, Adam R. Hall, Michael A. Filler, Jennifer L. Washburn, Paul H. Weigel, Jennifer E. Curtis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Polymer brushes are often used to functionalise surfaces. Here, the authors report on the creation of high-density, regenerating hyaluronan brushes using hyaluronan synthase enzymes which can be patterned by photo-deactivation and demonstrate biocomp
Externí odkaz:
https://doaj.org/article/512ee6ef6392433884c3d7aba09c8777
Autor:
Paul H. Weigel
Publikováno v:
Cells, Vol 9, Iss 11, p 2366 (2020)
Scavenger receptors perform essential functions, critical to maintaining mammalian physiologic homeostasis by continuously clearing vast numbers of biomolecules from blood, interstitial fluid and lymph. Stabilin-2 (Stab2) and the Hyaluronic Acid Rece
Externí odkaz:
https://doaj.org/article/8eac38c5190b4c2fae95cd60fd4c8a6a
Autor:
Paul H. Weigel
Publikováno v:
Biomolecules, Vol 9, Iss 9, p 454 (2019)
Since the discovery of a novel liver hyaluronan (HA) clearance receptor in 1981 by Laurent, Fraser and coworkers, 22 different ligands cleared by the renamed receptor (the Hyaluronan Receptor for Endocytosis (HARE); Stabilin-2 (Stab2)) were discovere
Externí odkaz:
https://doaj.org/article/49cf5054e6c5428ca512651c9de9f528
Publikováno v:
International Journal of Cell Biology, Vol 2015 (2015)
The hyaluronan (HA) receptor for endocytosis (HARE) is a multifunctional recycling clearance receptor for 14 different ligands, including HA and heparin (Hep), which bind to discrete nonoverlapping sites. Four different functional endocytic motifs (M
Externí odkaz:
https://doaj.org/article/4d36372870564c50bcc1b4448218da70
Publikováno v:
International Journal of Cell Biology, Vol 2015 (2015)
Externí odkaz:
https://doaj.org/article/7205bfd3a9cf4a598d59a8c733a0b2d5
Autor:
Paul H. Weigel
Publikováno v:
International Journal of Cell Biology, Vol 2015 (2015)
Hyaluronan (HA) biosynthesis has been studied for over six decades, but our understanding of the biochemical details of how HA synthase (HAS) assembles HA is still incomplete. Class I family members include mammalian and streptococcal HASs, the focus
Externí odkaz:
https://doaj.org/article/734c01b2678b42a58dbbf6fb11ba4d32
Autor:
Rampyari R. Walia, Paul H. Weigel
We describe a rapid ultrasensitive dual luciferase (Luc) assay for sequential detection of Cypridina Luc (CLuc) and Gaussia Luc (GLuc) in supernatant or lysates samples from transfected cells. Our assay is based on the principle that the bioluminesce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7dbe119a5ed147b75e2f47d0d149fa0
https://doi.org/10.21203/rs.3.pex-1867/v1
https://doi.org/10.21203/rs.3.pex-1867/v1
Autor:
Adam R. Hall, Jennifer E. Curtis, Hemaa Selvakumar, Jennifer L. Washburn, Jessica Faubel, Amar T. Mohabir, Paul H. Weigel, Elaheh Rahbar, Daniel T. Kovari, Wenbin Wei, Michael A. Filler, Felipe Rivas, Joanna Tsao, Michelle Krecker
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
Tailoring interfaces with polymer brushes is a commonly used strategy to create functional materials for numerous applications. Existing methods are limited in brush thickness, the ability to generate high-density brushes of biopolymers, and the pote
Autor:
Bruce A. Baggenstoss, Paul H. Weigel
Publikováno v:
Glycobiology. 27:868-877
The polydispersity of hyaluronan (HA) presents challenges for analyzing its solution properties, such as the relationship between mass and particle size. The broad mass range of natural HA (≤50-fold) makes molecular characterization difficult and a
Autor:
Fatima Banine, Stephen A. Back, Ben Emery, Daniel Shaver, Bruce A. Baggenstoss, Xi Gong, Taasin Srivastava, Matthew W. Hagen, Weiping Su, Edward N. Harris, Daniel L. Marks, Paul H. Weigel, Parham Diba, Justin M. Dean, Larry S. Sherman
Cerebral white matter injury (WMI) persistently disrupts myelin regeneration by oligodendrocyte progenitor cells (OPCs). We identified a specific bioactive hyaluronan fragment (bHAf) that downregulates myelin gene expression and chronically blocks OP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56702073e6327159d74de0187d3dc866
https://europepmc.org/articles/PMC5919806/
https://europepmc.org/articles/PMC5919806/