Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Paul H. Miller"'
Autor:
Philip A. Beer, David J.H.F. Knapp, Nagarajan Kannan, Paul H. Miller, Sonja Babovic, Elizabeth Bulaeva, Nima Aghaeepour, Gabrielle Rabu, Shabnam Rostamirad, Kingsley Shih, Lisa Wei, Connie J. Eaves
Publikováno v:
Stem Cell Reports, Vol 3, Iss 5, Pp 841-857 (2014)
Disrupted IKAROS activity is a recurrent feature of some human leukemias, but effects on normal human hematopoietic cells are largely unknown. Here, we used lentivirally mediated expression of a dominant-negative isoform of IKAROS (IK6) to block norm
Externí odkaz:
https://doaj.org/article/debcf6b44d1540b1884cfae480c423c6
Autor:
Paul H. Miller, Michael G. Morabito
Publikováno v:
Journal of Ship Production and Design. 39:75-88
_ The increasing availability of affordable finite element modeling software and computational fluid dynamics codes have given today’s sailing yacht designers tools that, in the past, were only available to designers of yachts competing in the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b243a28f64d2645f94b40327ca6fcfc5
https://doi.org/10.5957/jspd.10210025
https://doi.org/10.5957/jspd.10210025
Autor:
Garry P. Nolan, Sean C. Bendall, Carl L. Hansen, Connie J. Eaves, Fangwu Wang, Michael VanInsberghe, Colin A. Hammond, Paul H. Miller, Davide Pellacani, Nima Aghaeepour, Philip A. Beer, David J.H.F. Knapp
Publikováno v:
Blood. 133:927-939
Recent advances in single-cell molecular analytical methods and clonal growth assays are enabling more refined models of human hematopoietic lineage restriction processes to be conceptualized. Here, we report the results of integrating single-cell pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15fcce0c1303eea8c8f18302eaa1affd
https://doi.org/10.1182/blood-2018-10-878025
https://doi.org/10.1182/blood-2018-10-878025
Autor:
Michelle Moksa, Paul H. Miller, Martin Hirst, Fangwu Wang, Philip A. Beer, Tony Hui, R. Keith Humphries, Connie J. Eaves, Colin A. Hammond, Davide Pellacani, Nima Aghaeepour, Carl L. Hansen, Gabrielle Rabu, Marijn T J van Loenhout, David J.H.F. Knapp
Publikováno v:
Nature Cell Biology. 20:710-720
Elucidation of the identity and diversity of mechanisms that sustain long-term human blood cell production remains an important challenge. Previous studies indicate that, in adult mice, this property is vested in cells identified uniquely by their ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24d98b4edcb2f1a6347db482bea6d95d
https://doi.org/10.1038/s41556-018-0104-5
https://doi.org/10.1038/s41556-018-0104-5
Autor:
Margarita MacAldaz, Connie J. Eaves, Gabrielle Rabu, Naoto Nakamichi, Leonard D. Shultz, Kiran Dhillon, Paul H. Miller, R. Keith Humphries, Philip A. Beer, Alice M.S. Cheung, David J.H.F. Knapp
Publikováno v:
Experimental hematology
Xenograft models are transforming our understanding of the output capabilities of primitive human hematopoietic cells in vivo . However, many variables that affect posttransplantation reconstitution dynamics remain poorly understood. Here, we show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0955f37b99b81208278c0264b8aabfac
https://doi.org/10.1016/j.exphem.2016.12.012
https://doi.org/10.1016/j.exphem.2016.12.012
Autor:
Alireza Lorzadeh, Sitanshu Gakkhar, Misha Bilenky, Martin Hirst, Michelle Moksa, Paul H. Miller, Luolan Li, Colin A. Hammond, Annaick Carles, David J.H.F. Knapp, Alireza Heravi-Moussavi, Connie J. Eaves
Publikováno v:
Cell Reports. 17:2112-2124
SummaryNucleosome position, density, and post-translational modification are widely accepted components of mechanisms regulating DNA transcription but still incompletely understood. We present a modified native ChIP-seq method combined with an analyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44b5b7556d7ea3768dc76ba18db999a
https://doi.org/10.1016/j.celrep.2016.10.055
https://doi.org/10.1016/j.celrep.2016.10.055
Autor:
Stephen Couban, Connie J. Eaves, Kirk R. Schultz, Naoto Nakamichi, David Jones, Paul H. Miller, Gabrielle Rabu, David J.H.F. Knapp
Publikováno v:
Biology of Blood and Marrow Transplantation. 22:1945-1952
Plerixafor (P) together with granulocyte colony–stimulating factor (G) is now recognized as an important strategy for mobilizing hematopoietic cells for use in patients given myelosuppressive therapies. However, quantitative comparisons of their ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc845d980eb7ad764d70be1f494f9e26
https://doi.org/10.1016/j.bbmt.2016.07.023
https://doi.org/10.1016/j.bbmt.2016.07.023
Autor:
Margarita MacAldaz, Connie J. Eaves, Annelise Bennaceur-Griscelli, Melanie Kardel, Paul H. Miller, Ali G. Turhan
Publikováno v:
Experimental Hematology. 88:S71
Investigation of human hematopoietic stem cells (HSCs) has been revolutionized by advances in cell separation and clonal tracking of cells produced in transplanted patients and immunodeficient mice. However, methods able to expand them significantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a44b01a4a0134d254532229811de1005
https://doi.org/10.1016/j.exphem.2020.09.117
https://doi.org/10.1016/j.exphem.2020.09.117
Autor:
David J H F, Knapp, Colin A, Hammond, Fangwu, Wang, Nima, Aghaeepour, Paul H, Miller, Philip A, Beer, Davide, Pellacani, Michael, VanInsberghe, Carl, Hansen, Sean C, Bendall, Garry P, Nolan, Connie J, Eaves
Publikováno v:
Blood. 133(9)
Recent advances in single-cell molecular analytical methods and clonal growth assays are enabling more refined models of human hematopoietic lineage restriction processes to be conceptualized. Here, we report the results of integrating single-cell pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fa8aa08508adbe28d6c4e63a140698d
https://pubmed.ncbi.nlm.nih.gov/30622121
https://pubmed.ncbi.nlm.nih.gov/30622121
Autor:
Gabrielle Rabu, Brian J. Druker, Jefferson Terry, Nagarajan Kannan, Jerald P. Radich, Philip A. Beer, Ivan Sloma, Sonja Babovic, Elizabeth Bulaeva, Wendy N. Erber, Keith R. Loeb, Marc M. Loriaux, David J.H.F. Knapp, Paul H. Miller, Connie J. Eaves, Kathy Heel
Publikováno v:
Blood. 125:504-515
Without effective therapy, chronic-phase chronic myeloid leukemia (CP-CML) evolves into an acute leukemia (blast crisis [BC]) that displays either myeloid or B-lymphoid characteristics. This transition is often preceded by a clinically recognized, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e48fc7d5c1f482e2126ab81c217191
https://doi.org/10.1182/blood-2014-06-581173
https://doi.org/10.1182/blood-2014-06-581173