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pro vyhledávání: '"Paul H. Miller"'
Publikováno v:
(mt) Marine Technology; Apr2018, p7-13, 7p
Akademický článek
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Autor:
Paul H. Miller, Michael G. Morabito
Publikováno v:
Journal of Ship Production and Design. 39:75-88
_ The increasing availability of affordable finite element modeling software and computational fluid dynamics codes have given today’s sailing yacht designers tools that, in the past, were only available to designers of yachts competing in the most
Autor:
Philip A. Beer, David J.H.F. Knapp, Nagarajan Kannan, Paul H. Miller, Sonja Babovic, Elizabeth Bulaeva, Nima Aghaeepour, Gabrielle Rabu, Shabnam Rostamirad, Kingsley Shih, Lisa Wei, Connie J. Eaves
Publikováno v:
Stem Cell Reports, Vol 3, Iss 5, Pp 841-857 (2014)
Disrupted IKAROS activity is a recurrent feature of some human leukemias, but effects on normal human hematopoietic cells are largely unknown. Here, we used lentivirally mediated expression of a dominant-negative isoform of IKAROS (IK6) to block norm
Externí odkaz:
https://doaj.org/article/debcf6b44d1540b1884cfae480c423c6
Autor:
Garry P. Nolan, Sean C. Bendall, Carl L. Hansen, Connie J. Eaves, Fangwu Wang, Michael VanInsberghe, Colin A. Hammond, Paul H. Miller, Davide Pellacani, Nima Aghaeepour, Philip A. Beer, David J.H.F. Knapp
Publikováno v:
Blood. 133:927-939
Recent advances in single-cell molecular analytical methods and clonal growth assays are enabling more refined models of human hematopoietic lineage restriction processes to be conceptualized. Here, we report the results of integrating single-cell pr
Autor:
Michelle Moksa, Paul H. Miller, Martin Hirst, Fangwu Wang, Philip A. Beer, Tony Hui, R. Keith Humphries, Connie J. Eaves, Colin A. Hammond, Davide Pellacani, Nima Aghaeepour, Carl L. Hansen, Gabrielle Rabu, Marijn T J van Loenhout, David J.H.F. Knapp
Publikováno v:
Nature Cell Biology. 20:710-720
Elucidation of the identity and diversity of mechanisms that sustain long-term human blood cell production remains an important challenge. Previous studies indicate that, in adult mice, this property is vested in cells identified uniquely by their ab
Autor:
Margarita MacAldaz, Connie J. Eaves, Gabrielle Rabu, Naoto Nakamichi, Leonard D. Shultz, Kiran Dhillon, Paul H. Miller, R. Keith Humphries, Philip A. Beer, Alice M.S. Cheung, David J.H.F. Knapp
Publikováno v:
Experimental hematology
Xenograft models are transforming our understanding of the output capabilities of primitive human hematopoietic cells in vivo . However, many variables that affect posttransplantation reconstitution dynamics remain poorly understood. Here, we show th
Autor:
Alireza Lorzadeh, Sitanshu Gakkhar, Misha Bilenky, Martin Hirst, Michelle Moksa, Paul H. Miller, Luolan Li, Colin A. Hammond, Annaick Carles, David J.H.F. Knapp, Alireza Heravi-Moussavi, Connie J. Eaves
Publikováno v:
Cell Reports. 17:2112-2124
SummaryNucleosome position, density, and post-translational modification are widely accepted components of mechanisms regulating DNA transcription but still incompletely understood. We present a modified native ChIP-seq method combined with an analyt
Autor:
Stephen Couban, Connie J. Eaves, Kirk R. Schultz, Naoto Nakamichi, David Jones, Paul H. Miller, Gabrielle Rabu, David J.H.F. Knapp
Publikováno v:
Biology of Blood and Marrow Transplantation. 22:1945-1952
Plerixafor (P) together with granulocyte colony–stimulating factor (G) is now recognized as an important strategy for mobilizing hematopoietic cells for use in patients given myelosuppressive therapies. However, quantitative comparisons of their ab
Autor:
Margarita MacAldaz, Connie J. Eaves, Annelise Bennaceur-Griscelli, Melanie Kardel, Paul H. Miller, Ali G. Turhan
Publikováno v:
Experimental Hematology. 88:S71
Investigation of human hematopoietic stem cells (HSCs) has been revolutionized by advances in cell separation and clonal tracking of cells produced in transplanted patients and immunodeficient mice. However, methods able to expand them significantly