Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Paul H. Krolikowski"'
Autor:
Hakan Gunaydin, Bingfan Du, Victor J. Cee, Philip R. Olivieri, Stephanie D. Geuns-Meyer, Kathleen Panter Faber, Brian L. Hodous, Vinod F. Patel, Holly L. Deak, Hanh Nho Nguyen, Paul H. Krolikowski, Steven L. Hollis, Karina Romero, Laurie B. Schenkel
Publikováno v:
The Journal of Organic Chemistry. 77:3887-3906
Herein we describe a general three-step synthesis of 4-substituted chlorophthalazines in good overall yields. In the key step, N,N-dimethylaminophthalimide (8a) directs the selective monoaddition of alkyl, aryl, and heteroaryl organometallic reagents
Autor:
Christine M Dieckhaus, Thomas A. Baillie, Carmen Fernandez-Metzler, Paul H. Krolikowski, Richard King
Publikováno v:
Chemical research in toxicology. 18(4)
Characterization of S-linked conjugates of the endogenous tripeptide glutathione (gamma-glutamyl-cysteinylglycine, GSH) represents a valuable indirect approach for the identification of chemically reactive, electrophilic intermediates formed during t