Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Paul H. Evora"'
Autor:
Robert R. Luedtke, David Cohen, Martin Reivich, Robert H. Mach, Peggy A. Nowak, Richard E. Ehrenkaufer, Joel H. Greenberg, Thomas E. Morton, Paul H. Evora, Lingxiong Shao
Publikováno v:
Synapse. 19:177-187
A series of positron emission tomography (PET) imaging studies was conducted in a baboon with the benzamide derivatives [18F]2,3-dimethoxy N-9-(4-fluorobenzyl)-9-azabicyclo[3.3.1]nonan-3β-yl]benzamide ([18F]MABN) and [18F]2,3-dimethoxy-N-[1-(4-fluor
Publikováno v:
Applied Radiation and Isotopes. 45:465-472
Current methods of radioligand synthesis for the vesamicol receptor either utilize bioactive unlabeled precursors and/or generate unlabelled bioactive by-products. The presence of these compounds in the radiotracer preparation increases the risk of a
Autor:
Robert R. Luedtke, Theresa M. Filtz, Anand V. Rao, Thomas E. Morton, Peggy A. Nowak, Paul H. Evora, S.Todd Elder, Christopher D. Unsworth, James G. Scripko, Richard E. Ehrenkaufer, Perry B. Molinoff, Robert H. Mach
Publikováno v:
Nuclear Medicine and Biology. 20:777-794
[18F]4-Fluorobenzyl iodide ([18F]FBI) was prepared, and a series of model alkylation studies were conducted to determine its chemical reactivity toward nitrogen and sulfur nucleophiles of varying nucleophilicities. [18F]FBI was found to react rapidly
Autor:
P. L. Hoffman, Robert H. Mach, Peggy A. Nowak, James G. Scripko, V. A. Boundy, Christopher D. Unsworth, Robert R. Luedtke, Paul H. Evora, Joseph R. Jackson, S. T. Elder
Publikováno v:
Journal of medicinal chemistry. 36(23)
Two series of (N-benzylpiperidin-4-yl)- and (9-azabicyclo[3.3.1]nonan-3β-yl)benzamides were prepared, and in intro binding assays were used to measure the affinity of these compounds for dopamine D 2 , dopamine D 3 , serotonin 5-HT 2 , and α 2 -adr