Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Paul H Gordon"'
Autor:
Rebecca Banerjee, R Lee Mosley, Ashley D Reynolds, Alok Dhar, Vernice Jackson-Lewis, Paul H Gordon, Serge Przedborski, Howard E Gendelman
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2740 (2008)
Innate neuroimmune dysfunction is a pathobiological feature of amyotrophic lateral sclerosis (ALS). However, links, if any, between disease and adaptive immunity are poorly understood. Thus, the role of T cell immunity in disease was investigated in
Externí odkaz:
https://doaj.org/article/6437c68b35684467998cac35abbdcfbb
Autor:
Katrina Gwinn, Roderick A Corriveau, Hiroshi Mitsumoto, Kate Bednarz, Robert H Brown, Merit Cudkowicz, Paul H Gordon, John Hardy, Edward J Kasarskis, Petra Kaufmann, Robert Miller, Eric Sorenson, Rup Tandan, Bryan J Traynor, Josefina Nash, Alex Sherman, Matthew D Mailman, James Ostell, Lucie Bruijn, Valerie Cwik, Stephen S Rich, Andrew Singleton, Larry Refolo, Jaime Andrews, Ran Zhang, Robin Conwit, Margaret A Keller, ALS Research Group
Publikováno v:
PLoS ONE, Vol 2, Iss 12, p e1254 (2007)
Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease (MND). It is currently incurable and treatment is largely limited to supportive care. Family history is associated with an increased risk of ALS, and many Mendelian c
Externí odkaz:
https://doaj.org/article/810eaf8daa3c4dc8ab0673f7e64b23f9
Autor:
Blandine Madji Hounoum, Stéphane Beltran, Philippe Corcia, Christian R. Andres, Paul H. Gordon, Franck Patin, Hélène Blasco, François Maillot, Diane Dufour-Rainfray
Publikováno v:
CNS Neuroscience & Therapeutics. 21:651-656
Summary Aims Vitamin D deficiency has been associated with poorer prognosis in ALS. Better understanding of the role of vitamin D in ALS is needed to determine whether trials of systematic supplementation are justified. Our aim was to report vitamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d10b2c32aeed9a32856eb129e66362
https://doi.org/10.1111/cns.12423
https://doi.org/10.1111/cns.12423
Autor:
Michael L. Bartholomew, Robert C. Holman, James E. Cheek, Jason M. Mehal, Paul H. Gordon, Andrew S. Rowland
Publikováno v:
Movement Disorders. 30:714-720
Parkinson's disease (PD) is largely unstudied among American Indians. Unique populations might harbor clues to elusive causes. We describe the incidence and prevalence of PD among Navajo people residing in the Navajo Nation, home to the largest Ameri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::224a4ef20fefaf485765ba091a1afe14
https://doi.org/10.1002/mds.26147
https://doi.org/10.1002/mds.26147
Publikováno v:
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 16:252-257
Our objective was to examine the strength of evidence in support of the paraneoplastic syndrome (PNS) as one cause of ALS and, if the association appears more likely than chance, determine which features of ALS imply concurrent malignancy. We reviewe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2dd09361d77a6bc1b6fbe67559dc06
https://doi.org/10.3109/21678421.2014.965178
https://doi.org/10.3109/21678421.2014.965178
Autor:
Jesse D. Blanton, Robert C. Holman, James E. Cheek, Jason M. Mehal, Paul H. Gordon, Neil M. Vora
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 90:755-759
Encephalitis produces considerable morbidity in the United States, but morbidity rates among American Indian/Alaska Native (AI/AN) people have not been described. Hospitalization records listing an encephalitis diagnosis were analyzed by using Indian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f624fae42ea2dfe45e70c11ba543a633
https://doi.org/10.4269/ajtmh.13-0420
https://doi.org/10.4269/ajtmh.13-0420
Autor:
Paul H. Gordon, Maria del Mar Amador, Philippe Corcia, Patrick Vourc'h, Philippe Couratier, Vincent Meininger, Anne-Marie Guennoc, Christian R. Andres, Hélène Blasco
Publikováno v:
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 17:301-303
Excessive repeats of the hexaplet GGGGCC in intron 1 of the C9orf72 gene are the most frequent genetic mutations so far identified that are linked to amyotrophic lateral sclerosis (ALS) and frontot...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e21078462d6b3038603942ffb5b001
https://doi.org/10.3109/21678421.2015.1113298
https://doi.org/10.3109/21678421.2015.1113298
Publikováno v:
Neurodegenerative Disease Management. 3:427-444
SUMMARY Amyotrophic lateral sclerosis is an idiopathic, incurable neurodegenerative disease that is fatal for most patients in less than 3 years from the time weakness first appears. Alongside identification of etiologies and stronger neuroprotective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5271ec5c424826aec175c7de00d83540
https://doi.org/10.2217/nmt.13.43
https://doi.org/10.2217/nmt.13.43
Autor:
Patrick Vourc'h, Gérard Besson, Charlotte Veyrat-Durebex, Olivier Augereau, Philippe Corcia, William Camu, Peter M. Andersen, Paul H. Gordon, Christian R. Andres, Catherine Antar, François Salachas, Nathalie Bernard-Marissal, Claire Sunyach, Vincent Meininger, Joelle Khederchah, Kevin Mouzat, Brigitte Pettmann, Yves Olivier Guettard, Hélène Blasco
Publikováno v:
Human Mutation. 34:953-960
The dihydropyrimidinase-like 3 (DPYSL3) or Collapsin Response Mediator Protein 4a (CRMP4a) expression is modified in neurodegeneration and is involved in several ALS-associated pathways including axonal transport, glutamate excitotoxicity, and oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0016efab20847bd8e2485136d8a5c8f
https://doi.org/10.1002/humu.22329
https://doi.org/10.1002/humu.22329
Autor:
Paul H. Gordon
Publikováno v:
Aging and Disease. :295-310
Amyotrophic lateral sclerosis (ALS), first described by Jean-Martin Charcot in the 1870s, is an age-related disorder that leads to degeneration of motor neurons. The disease begins focally in the central nervous system and then spreads relentlessly.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9ec7fe102b897f9cf5908242912f72
https://doi.org/10.14336/ad.2013.0400295
https://doi.org/10.14336/ad.2013.0400295