Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Paul H, Frankel"'
Autor:
Brad Nakamura, Rosemary Senguttuvan, Nora H. Ruel, Paul H. Frankel, Susan E. Yost, Sarah Cole, Sue Chang, Alexander Jung, Melissa Eng, Raechelle Tinsley, Daphne Stewart, Edward Wang, Joshua Cohen, Jeannine Villella, Richard L. Whelan, Amit Merchea, Danielle K. DePeralta, Mihaela Cristea, Mark T. Wakabayashi, Mustafa Raoof, Thanh Hue Dellinger
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionLow grade serous ovarian carcinoma (LGSOC) is a rare subtype of ovarian cancer (OC) that is challenging to treat due to its relative chemoresistance. Given that LGSOC patients often recur in the peritoneal cavity, novel intraperitoneal (I
Externí odkaz:
https://doaj.org/article/6bec2ec2e11647dab2a24f0674491ac4
Autor:
Flavia Chiuppesi, John A. Zaia, Katelyn Faircloth, Daisy Johnson, Minh Ly, Veronica Karpinski, Corinna La Rosa, Jennifer Drake, Joan Marcia, Ann Marie Acosta, Shannon Dempsey, Randy A. Taplitz, Qiao Zhou, Yoonsuh Park, Sandra Ortega Francisco, Teodora Kaltcheva, Paul H. Frankel, Steven Rosen, Felix Wussow, Sanjeet Dadwal, Don J. Diamond
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104745- (2022)
Summary: Cell-mediated immunity may contribute to providing protection against SARS-CoV-2 and its variants of concern (VOC). We developed COH04S1, a synthetic multiantigen modified vaccinia Ankara (MVA)-based COVID-19 vaccine that stimulated potent s
Externí odkaz:
https://doaj.org/article/7ee89bd0a1624ab7a1390db06348e249
Autor:
Flavia Chiuppesi, PhD, John A Zaia, ProfMD, Paul H Frankel, ProfPhD, Rodica Stan, PhD, Jennifer Drake, RN, Brenda Williams, RN, Anne Marie Acosta, LVN, Karyn Francis, RN, Randy A Taplitz, ProfMD, Janet K Dickter, MD, Sanjeet Dadwal, MD, Alfredo G Puing, MD, Deepa D Nanayakkara, MD, Patricia Ash, RN, Yujie Cui, MS, Heidi Contreras, PhD, Corinna La Rosa, PhD, Katrin Tiemann, PhD, Yoonsuh Park, PhD, Joybelle Medina, MS, Angelina Iniguez, MS, Qiao Zhou, MS, Veronica Karpinski, MS, Daisy Johnson, MS, Katelyn Faircloth, MS, Teadora Kaltcheva, PhD, Jenny Nguyen, MS, Mindy Kha, MS, Vu H Nguyen, PhD, Sandra Ortega Francisco, PhD, Alba Grifoni, PhD, Angela Wong, MS, Alessandro Sette, PhD, Felix Wussow, PhD, Don J Diamond, ProfPhD
Publikováno v:
The Lancet Microbe, Vol 3, Iss 4, Pp e252-e264 (2022)
Summary: Background: COH04S1, a synthetic attenuated modified vaccinia virus Ankara vector co-expressing SARS-CoV-2 spike and nucleocapsid antigens, was tested for safety and immunogenicity in healthy adults. Methods: This combined open-label and ran
Externí odkaz:
https://doaj.org/article/19a51d8eae2e44b187fd29cbd3dee5ce
Ethics and Clinical Research: Improving Transparency and Informed Consent in Phase I Oncology Trials
Autor:
Paul H. Frankel, Susan Groshen, Jan H. Beumer, Laura Cleveland, Edward S. Kim, Judith E. Karp
Publikováno v:
Journal of Clinical Oncology. 41:2155-2158
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8233890130990e53b70b055f788e8b5a
https://doi.org/10.1200/jco.22.01736
https://doi.org/10.1200/jco.22.01736
Autor:
Colt A. Egelston, Weihua Guo, Susan E. Yost, Xuan Ge, Jin Sun Lee, Paul H. Frankel, Yujie Cui, Christopher Ruel, Daniel Schmolze, Mireya Murga, Aileen Tang, Norma Martinez, Misagh Karimi, George Somlo, Peter Lee, James Waisman, Yuan Yuan
Publikováno v:
Cancer Research. 83:OT2-08
Background: Combination of immune checkpoint inhibitor pembrolizumab and chemotherapy are standard of care therapy for patients with programmed death-ligand 1 positive (PD-L1+) metastatic triple negative breast cancer (mTNBC). However, a greater unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::544d072e62f00b294a13384ba8ab9cdc
https://doi.org/10.1158/1538-7445.sabcs22-ot2-08-03
https://doi.org/10.1158/1538-7445.sabcs22-ot2-08-03
Autor:
Jeffrey Y.C. Wong, David M. Yamauchi, Vikram Adhikarla, Jennifer Simpson, Paul H. Frankel, Yuman Fong, Kurt A. Melstrom, Yi-jen Chen, Behrooz D. Salehian, Yanghee Woo, Savita V. Dandapani, David M. Colcher, Erasmus K. Poku, Paul J. Yazaki, Anna M. Wu, John E. Shively
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 38:26-37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c17024ae04a3291cf8bab39505adcc3
https://doi.org/10.1089/cbr.2022.0028
https://doi.org/10.1089/cbr.2022.0028
Autor:
Ting-Fang He, Susan E Yost, Paul H Frankel, Andrew Dagis, Yu Cao, Roger Wang, Anthony Rosario, Travis Yiwey Tu, Shawn Solomon, Daniel Schmolze, Joanne Mortimer, Peter Lee, Yuan Yuan
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229955 (2020)
The evolutionary changes in immune profiles of triple negative breast cancer (TNBC) are not well understood, although it is known that immune checkpoint inhibitors have diminished activity in heavily pre-treated TNBC patients. This study was designed
Externí odkaz:
https://doaj.org/article/33b321abbf7b469cb8ac3450b97d58a2
Autor:
Sayeh M. Lavasani, George Somlo, Susan E. Yost, Paul H. Frankel, Christopher Ruel, Yujie Cui, Mireya Murga, Aileen Tang, Norma Martinez, Laura Kruper, Lusine Tumyan, Daniel Schmolze, Christina Yeon, Yuan Yuan, James R. Waisman, Joanne Mortimer
Publikováno v:
Cancer. 129:740-749
The objective of this study was to evaluate the safety and efficacy of nab-paclitaxel, trastuzumab, and pertuzumab as neoadjuvant therapy (NAT) in patients with human epidermal growth factor receptor 2 HER2+ breast cancer (HER2+ BC) to determine path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5cf80e5c152c33037dc84e544cb2d61
https://doi.org/10.1002/cncr.34589
https://doi.org/10.1002/cncr.34589
Autor:
Karen L. Reckamp, Paul H. Frankel, Nora Ruel, Philip C. Mack, Barbara J. Gitlitz, Tianhong Li, Marianna Koczywas, Shirish M. Gadgeel, Mihaela C. Cristea, Chandra P. Belani, Edward M. Newman, David R. Gandara, Primo N. Lara
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Introduction: Mesenchymal epidermal transition and vascular endothelial growth factor pathways are important in mediating non-small cell lung cancer (NSCLC) tumorigenesis and epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) res
Externí odkaz:
https://doaj.org/article/ca57b5df964545278ac1f00ea2e76a4d
Autor:
Michelle Afkhami, Daniel Schmolze, Susan E Yost, Paul H Frankel, Andrew Dagis, Idoroenyi U Amanam, Milhan Telatar, Kim Nguyen, Kim Wai Yu, Thehang Luu, Raju Pillai, Patricia A Aoun, Joanne Mortimer, Yuan Yuan
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224726 (2019)
The goal of this study is to characterize the genomic and immune profiles of metaplastic breast cancer (MpBC) and identify the association with survival through an analysis of archived tumor tissue. A next-generation sequencing-based mutational assay
Externí odkaz:
https://doaj.org/article/55bd025cde8f4ee8857bf5de40ab60c7