Endogenous Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Plays a Protective Effect Against Noise-Induced Hearing Loss

Autor: Jérôme Ruel, Matthieu J. Guitton, Paul Gratias, Marc Lenoir, Sanbing Shen, Jean-Luc Puel, Philippe Brabet, Jing Wang

Publikováno v: Frontiers in Cellular Neuroscience, Vol 15 (2021)

Pituitary adenylyl cyclase-activating polypeptide (PACAP) is a member of the vasoactive intestinal polypeptide (VIP)-the secretin-glucagon family of neuropeptides. They act through two classes of receptors: PACAP type 1 (PAC1) and type 2 (VPAC1 and V

Externí odkaz: https://doaj.org/article/fb1c3c219f4446ea9e62abbc1c4503dc

Impulse Noise Induced Hidden Hearing Loss, Hair Cell Ciliary Changes and Oxidative Stress in Mice

Autor: J C Ceccato, Jean-Luc Puel, Corentin Affortit, Sylvie Pucheu, Jing Wang, François Casas, Florence François, Paul Gratias, Jamal Nasr, Rémy Pujol

Publikováno v: Antioxidants, Vol 10, Iss 1880, p 1880 (2021)
Antioxidants
Antioxidants, MDPI, 2021, 10 (12), 17p. ⟨10.3390/antiox10121880⟩
Antioxidants; Volume 10; Issue 12; Pages: 1880

International audience; Recent studies demonstrated that reversible continuous noise exposure may induce a temporary threshold shift (TTS) with a permanent degeneration of auditory nerve fibers, although hair cells remain intact. To probe the impact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62cf7445926b16cf37f075f15ec50514
https://www.mdpi.com/2076-3921/10/12/1880