Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Paul Golby"'
Autor:
Elena Hailu, Daire Cantillon, Carlos Madrazo, Graham Rose, Paul R. Wheeler, Paul Golby, Bethlehem Adnew, Sebastien Gagneux, Abraham Aseffa, Stephen V. Gordon, Iñaki Comas, Douglas B. Young, Simon J. Waddell, Gerald Larrouy-Maumus, Stefan Berg
Publikováno v:
Microbial Genomics. 9
16 páginas, 6 figuras, 2 tablas
Lineage 7 (L7) emerged in the phylogeny of the Mycobacterium tuberculosis complex (MTBC) subsequent to the branching of 'ancient' lineage 1 and prior to the Eurasian dispersal of 'modern' lineages 2, 3 and 4. In
Lineage 7 (L7) emerged in the phylogeny of the Mycobacterium tuberculosis complex (MTBC) subsequent to the branching of 'ancient' lineage 1 and prior to the Eurasian dispersal of 'modern' lineages 2, 3 and 4. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6838ac86838923edd63a0a14bb73a2d
https://doi.org/10.1099/mgen.0.001011
https://doi.org/10.1099/mgen.0.001011
Autor:
Marcelo Abel Soria, Elizabeth Andrea Garcia, Rosana Valeria Rocha, Fabiana Bigi, Cristina Lourdes Vázquez, Federico Carlos Blanco, Marina Andrea Forrellad, Paul Golby, Maria Montserrat Pujadas Bigi
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Mycobacterium bovis is the causative agent of bovine tuberculosis and is a member of Mycobacterium tuberculosis complex, which causes tuberculosis in a number of mammals including humans. Previous studies have shown that the genes encoding the two-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35ef0fc389f11cd71efdb4a3f5bc650
https://www.sciencedirect.com/science/article/pii/S0378113518300725
https://www.sciencedirect.com/science/article/pii/S0378113518300725
Publikováno v:
Cancer Research. 79:1931-1931
Characterizing the relationship between pharmacokinetics (PK), pharmacodynamics (PD) and efficacy is critical in the discovery and development of new drugs, schedules and combinations. The PK/PD/efficacy relationship has historically been characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ec079b7223ef62e9d7d87cb4c1a5cdd
https://doi.org/10.1158/1538-7445.am2019-1931
https://doi.org/10.1158/1538-7445.am2019-1931
Autor:
Yurena Navarro, Javier Bezos, Alicia Aranaz, Ana Mateos, Noel H. Smith, Beatriz Romero, Paul Golby, Lucas Domínguez, Glyn Hewinson, Lucía de Juan, Darío García-de-Viedma, Sabrina Rodriguez-Campos
Publikováno v:
Journal of Clinical Microbiology. 51:3658-3665
Mycobacterium bovis populations in countries with persistent bovine tuberculosis usually show a prevalent spoligotype with a wide geographical distribution. This study applied mycobacterial interspersed repetitive-unit–variable-number tandem-repeat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4234c3846a2b1aeae8f203eeefc7d8c
https://doi.org/10.1128/jcm.01271-13
https://doi.org/10.1128/jcm.01271-13
Publikováno v:
Cancer Research. 78:LB-044
Combination dosing regimens offer the opportunity to improve the efficacy or better manage the toxicity profile of approved drugs and new therapies under development. Mouse xenograft models are currently used to select optimal combinations and admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dc6ffb12c52f10d9c557c635c10e64e
https://doi.org/10.1158/1538-7445.am2018-lb-044
https://doi.org/10.1158/1538-7445.am2018-lb-044
Autor:
Pablo Mendoza Lopez, Kevin C. Conlon, Julio Polaina, Antonio Suárez García, Stephen V. Gordon, Javier Nunez Garcia, R. Glyn Hewinson, Esen Wooff, M. Carmen Garcia Pelayo, Ana Camacho, Paul Golby
Publikováno v:
Microbiology; Vol 156
Microbiology
Microbiology
A number of single-nucleotide polymorphisms (SNPs) have been identified in the genome of Mycobacterium bovis BCG Pasteur compared with the sequenced strain M. bovis 2122/97. The functional consequences of many of these mutations remain to be describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd90347ed4f2d8a7c7ff19b667f7471f
Autor:
Ángel Adrián Cataldi, Fabiana Bigi, Paul Golby, María Verónica Bianco, Carmen Garcia-Pelayo, Marcelo Abel Soria, Stephen V. Gordon, Federico Carlos Blanco, Martín José Zumárraga, Javier Nunez-Garcia
Publikováno v:
Microbes and Infection. 11:956-963
The identification of factors involved in the interaction of Mycobacterium bovis with the hosts will lead to new strategies to control bovine tuberculosis. In this study we compared the transcriptional profile of an attenuated M. bovis strain and a v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7db6d7fde38ccf50281cb40e08031f1
https://doi.org/10.1016/j.micinf.2009.06.006
https://doi.org/10.1016/j.micinf.2009.06.006
Autor:
Paul Golby, Laura Inés Klepp, Federico Carlos Blanco, Fabiana Bigi, Maria del Carmen García-Pelayo, María Verónica Bianco, Javier Nunez-Garcia, Stephen V. Gordon, María de la Paz Santangelo, Marcelo Abel Soria, Mary Jackson, Ángel Adrián Cataldi
Publikováno v:
Microbiology. 155:2245-2255
The mce operons constitute four homologous regions in the Mycobacterium tuberculosis genome, each of which has 8–13 ORFs. Although the function of the Mce protein family has not been clearly established, its members are believed to be membrane lipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8c726d152971ff1fe12d5725fcbfa8
https://doi.org/10.1099/mic.0.027086-0
https://doi.org/10.1099/mic.0.027086-0
Autor:
Karen E. Logan, R. Glyn Hewinson, Paul J. Cockle, Javier Nunez, Stephen V. Gordon, Jason Hinds, Philip J. Hogarth, Paul Golby, H. Martin Vordermeier, Katie J. Ewer
Publikováno v:
ResearcherID
Genome sequencing of Mycobacterium tuberculosis complex members has accelerated the search for new disease-control tools. Antigen mining is one area that has benefited enormously from access to genome data. As part of an ongoing antigen mining progra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878f3b644c961107e5b8f00f37cb9072
https://doi.org/10.1099/mic.0.2007/014548-0
https://doi.org/10.1099/mic.0.2007/014548-0
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 97
Summary Coordinated regulation of gene expression is essential for pathogen adaptation in vivo . Understanding the control of these virulence circuits in the TB pathogen Mycobacterium tuberculosis is a key challenge if we are to increase our basic un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c19b06bdc39a6fe6ed410f0ecda7193
https://pubmed.ncbi.nlm.nih.gov/26615221
https://pubmed.ncbi.nlm.nih.gov/26615221