Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Paul Garside"'
Autor:
Catriona T. Prendergast, Robert A. Benson, Hannah E. Scales, Caio Santos Bonilha, John J. Cole, Iain McInnes, James M. Brewer, Paul Garside
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
Mechanisms governing entry and exit of immune cells into and out of inflamed joints remain poorly understood. We sought herein to identify the key molecular pathways regulating such migration. Using murine models of inflammation in conjunction with m
Externí odkaz:
https://doaj.org/article/5d1175430835444c926fbbd904727585
Autor:
Alexandre Girard, Anneli Cooper, Samuel Mabbott, Barbara Bradley, Steven Asiala, Lauren Jamieson, Caroline Clucas, Paul Capewell, Francesco Marchesi, Matthew P Gibbins, Franziska Hentzschel, Matthias Marti, Juan F Quintana, Paul Garside, Karen Faulds, Annette MacLeod, Duncan Graham
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010060 (2021)
Human African Trypanosomiasis (HAT) has been responsible for several deadly epidemics throughout the 20th century, but a renewed commitment to disease control has significantly reduced new cases and motivated a target for the elimination of Trypanoso
Externí odkaz:
https://doaj.org/article/77d6c85f7c8a4ff8b7be5e61060b8aa3
Autor:
Omar A. Alfituri, Juan F. Quintana, Annette MacLeod, Paul Garside, Robert A. Benson, James M. Brewer, Neil A. Mabbott, Liam J. Morrison, Paul Capewell
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/9d03bc7f88f44e9eb670e04cf4dded3a
Autor:
Shaima Al Khabouri, Robert A. Benson, Catriona T. Prendergast, Joshua I. Gray, Thomas D. Otto, James M. Brewer, Paul Garside
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Effective tolerogenic intervention in Rheumatoid Arthritis (RA) will rely upon understanding the evolution of articular antigen specific CD4 T cell responses. TCR clonality of endogenous CD4 T cell infiltrates in early inflammatory arthritis was asse
Externí odkaz:
https://doaj.org/article/f24f091353d845b49a310b48bae536ce
Publikováno v:
Journal of Conservation and Museum Studies, Vol 19, Iss 1 (2021)
The British Library’s conservation department faced a significant range of challenges arising from the COVID-19 situation and the limited time available to respond to them. By drawing on areas in which the department already had particular strength
Externí odkaz:
https://doaj.org/article/6d8b9c20fdcb4b9d9201a1b7e2749fae
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The junctional adhesion molecule-A (JAM-A) is a cell surface adhesion molecule expressed on platelets, epithelial cells, endothelial cells and leukocytes (e. g. monocytes and dendritic cells). JAM-A plays a relevant role in leukocyte trafficking and
Externí odkaz:
https://doaj.org/article/bc2d700e834344a08d660c40e5ec753d
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Malaria is caused by apicomplexan parasites of the genus Plasmodium. While infection continues to pose a risk for the majority of the global population, the burden of disease mainly resides in Sub-Saharan Africa. Although immunity develops against di
Externí odkaz:
https://doaj.org/article/fa689ace3696499499ac9830b9c00484
Autor:
Omar A. Alfituri, Juan F. Quintana, Annette MacLeod, Paul Garside, Robert A. Benson, James M. Brewer, Neil A. Mabbott, Liam J. Morrison, Paul Capewell
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
African trypanosomes are single-celled extracellular protozoan parasites transmitted by tsetse fly vectors across sub-Saharan Africa, causing serious disease in both humans and animals. Mammalian infections begin when the tsetse fly penetrates the sk
Externí odkaz:
https://doaj.org/article/0534fa510d984e8e8d6b6f571924ce7f
Autor:
Jonathan Noonan, Gianluca Grassia, Neil MacRitchie, Paul Garside, Tomasz J. Guzik, Angela C. Bradshaw, Pasquale Maffia
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Atherosclerosis is a complex inflammatory pathology underpinning cardiovascular diseases (CVD), which are the leading cause of death worldwide. The interplay between vascular stromal cells and immune cells is fundamental to the progression and outcom
Externí odkaz:
https://doaj.org/article/5dfcc9a1d25940f1b06bfc4cfc86fa26
Autor:
Alan J. Hayes, Sanket Rane, Hannah E. Scales, Gavin R. Meehan, Robert A. Benson, Asher Maroof, Juliane Schroeder, Michio Tomura, Neil Gozzard, Andrew J. Yates, Paul Garside, James M. Brewer
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Initiation of adaptive immunity involves distinct migratory cell populations coming together in a highly dynamic and spatially organized process. However, we lack a detailed spatiotemporal map of these events due to our inability to track the fate of
Externí odkaz:
https://doaj.org/article/990e096a122f42f8ab6e7b00751d7cba