Výsledky vyhledávání - "Paul G. Roybal"

EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis

Autor: Jingjing Sun, Robert E. Maxson, Youzhen Yen, Nancy L. Wu, Man-Chun Ting, Paul G. Roybal, Liqiong Liu

Publikováno v: Development. 136:855-864

Heterozygous loss of Twist1 function causes coronal synostosis in both mice and humans. We showed previously that in mice this phenotype is associated with a defect in the neural crest-mesoderm boundary within the coronal suture, as well as with a re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058ca004e68d48a8cead3cd5c644bb10
https://doi.org/10.1242/dev.028605

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Inactivation of Msx1 and Msx2 in neural crest reveals an unexpected role in suppressing heterotopic bone formation in the head

Autor: Christopher A. Schafer, Jingjing Sun, Robert E. Maxson, Nancy L. Wu, Paul G. Roybal, Man-Chun Ting

Publikováno v: Developmental Biology. (1-2):28-39

In an effort to understand the morphogenetic forces that shape the bones of the skull, we inactivated Msx1 and Msx2 conditionally in neural crest. We show that Wnt1-Cre inactivation of up to three Msx1/2 alleles results in a progressively larger defe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d338470f1e0323d07c7b04dae3dcd1af

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