Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Paul G. Martin"'
Autor:
Sally Bannan, Paul G. Martin
Publikováno v:
British Journal of Haematology. 101:455-461
The relative contribution of full-dose aprotinin, used with heparin-bonded surfaces, to contact activation during cardiopulmonary bypass was examined. In vitro Carmeda-bonded cardiopulmonary bypass circuits were perfused with whole blood anticoagulat
Autor:
Yi Tian, Saeed Ashraf, Kevin G. Watterson, John Butler, Simon Lintin, Nigel R. Saunders, Paul G Martin, Dahlia Cowan
Publikováno v:
The Annals of Thoracic Surgery. 65:480-484
The nonocclusive centrifugal pump is used for cardiopulmonary bypass (CPB) and mechanical cardiac assistance. This study examined its impact on proinflammatory cytokine release.Forty-one patients undergoing elective coronary artery bypass grafting we
Publikováno v:
The Annals of Thoracic Surgery. 64:1790-1794
Background . Heparin bonding of the cardiopulmonary bypass (CPB) circuit may be associated with a reduced inflammatory response and improved clinical outcome. The relative contribution of a heparin-bonded oxygenator (ie, >80% of circuit surface area)
Autor:
Fracs Kevin G Watterson, Frcs Saeed Ashraf, Ffrca Ranjit Chatrath, Frcs Unnikrishnan Nair, Frcs Nigel R Saunders, Paul G Martin, MCh Yi Tian, Dalia Cowan
Publikováno v:
The Annals of Thoracic Surgery. 63:68-73
Cytokines are implicated in the pathogenesis of the "whole-body inflammatory response" that may complicate the period after cardiopulmonary bypass (CPB). Low-Dose aprotinin in the pump during CPB has been shown to improve postoperative hemostasis and
Autor:
Alison Jennings, Paul G Martin, Simon R. Stubington, Duncan R. Walker, Kenneth Newton, Christopher M.R. Satur, Cengiz Gebitekin
Publikováno v:
The Annals of Thoracic Surgery. 59:921-927
Hypomagnesemia and depletion of the body's magnesium stores is known to be associated with an increased incidence of both cardiac arrhythmias and neurological irritability. In a two-part prospective study we have evaluated whether magnesium deficienc
Publikováno v:
Blood Coagulation & Fibrinolysis. 5:17-22
Young adults with cyanotic congenital heart disease have a high incidence of respiratory and haemostatic problems. Activated neutrophils release vasoactive and chemotactic factors which result in endothelial injury, lung parenchymal damage and the ac
Publikováno v:
Blood Coagulation & Fibrinolysis. 3:183-192
Significant postoperative bleeding following open-heart surgery is often ascribed to the so-called heparin 'rebound' phenomenon and as such is treated with additional empiric doses of protamine sulphate. However, inappropriate protamine administratio
Publikováno v:
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 12(6)
Objective: Cardiopulmonary bypass (CPB) causes significant morbidity in paediatric patients, yet the mechanisms involved in the related inflammatory processes (resulting in capillary leak and edema) are poorly understood. Moreover, earlier palliative
Autor:
Saeed Ashraf, Riaf Shaikh, Malcolm Parsloe, Dehlia Cowan, Yi Tian, Paul G Martin, Kevin G. Watterson
Publikováno v:
Journal of cardiothoracic and vascular anesthesia. 11(6)
Objective: It has been proposed that nonocclusive centrifugal pumps may elicit less blood cell trauma and hence a reduced inflammatory response than standard roller pumps. However, there have been no reports describing the impact of such pumps on pro
Publikováno v:
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 12(2)
OBJECTIVE It is generally agreed that when the blood contact surfaces of a cardiopulmonary bypass circuit are treated with a layer of heparin molecules the activation of the humoral pathways is attenuated. However, there is still debate as to whether