Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Paul G. J. van Stralen"'
Autor:
Eric P. Krenning, Roelof Docter, Theo J. Visser, M. E. Everts, Georg Hennemann, Edith C. H. Friesema, Paul G. J. van Stralen
Publikováno v:
Endocrinology. 138:1841-1846
The present study was conducted to explore the possible use of Xenopus laevis oocytes for the expression cloning of cell membrane transporters for iodothyronines. Injection of stage V–VI X. laevis oocytes with 23 ng Wistar rat liver polyadenylated
Reduced T3 deiodination by the human hepatoblastoma cell line HepG2 caused by deficient T3 sulfation
Autor:
Roel Docter, Eric P. Krenning, Marion de Jong, Hans J. van der Hoek, Paul G. J. van Stralen, Georg Hennemann, Chen F. Lim
Publikováno v:
Biochimica et biophysica acta. 1157(1)
Type I deiodination of T3 sulfate occurs at a Vmax that is 30-fold higher as compared to T3, both in rat and in human liver homogenates. We now present data showing lack of T3 deiodination by a human liver derived hepatoblastoma cell line, HepG2, cau