Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Paul G. Winyard"'
Publikováno v:
Skin Health and Disease, Vol 4, Iss 3, Pp n/a-n/a (2024)
Abstract Background Incontinence Associated Dermatitis (IAD) is a type of skin inflammation caused by chronic exposure to urine and/or faeces. Current treatment strategies involve creating a barrier between the skin and urine/faeces rather than targe
Externí odkaz:
https://doaj.org/article/b589451557de4b12ab1a9ee0a7522116
Publikováno v:
Antioxidants, Vol 13, Iss 3, p 269 (2024)
The addition of hydrogen peroxide (H2O2) to cultured cells is widely used as a method to modulate redox-regulated cellular pathways, including the induction of programmed cell death in cell culture experiments and the testing of pro- and antioxidant
Externí odkaz:
https://doaj.org/article/c8a0fb269d5e4231b237cb806c998897
Autor:
Sotiris Kyriakou, Nikoletta Demosthenous, Tom Amery, Kyle J. Stewart, Paul G. Winyard, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 82 (2024)
Phenethyl isothiocyanate (PEITC) is a secondary metabolic product yielded upon the hydrolysis of gluconasturtiin and it is highly accumulated in the flowers of watercress. The aim of the current study was to assess the role of a naturally derived PEI
Externí odkaz:
https://doaj.org/article/2d6cf5720aac4d71821fc712fd477ed6
Autor:
Sotiris Kyriakou, Louiza Potamiti, Nikoletta Demosthenous, Tom Amery, Kyle Stewart, Paul G. Winyard, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis
Publikováno v:
Nutrients, Vol 15, Iss 18, p 4044 (2023)
The aim of the current study was to (i) extract isolated fractions of watercress flowers enriched in polyphenols, phenethyl isothiocyanate and glucosinolates and (ii) characterize the anticancer mode of action of non-lethal, sub-lethal and lethal con
Externí odkaz:
https://doaj.org/article/dc154627d0954d9187365deb43eff9e3
Autor:
Sotiris Kyriakou, Kyriaki Michailidou, Tom Amery, Kyle Stewart, Paul G. Winyard, Dimitrios T. Trafalis, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Watercress (Nasturtium officinale) is a rich source of secondary metabolites with disease-preventing and/or health-promoting properties. Herein, we have utilized extraction procedures to isolate fractions of polyphenols, glucosinolates and isothiocya
Externí odkaz:
https://doaj.org/article/bc058b1b57d64b9e85f7fad606de1873
Publikováno v:
Nutrients, Vol 15, Iss 3, p 784 (2023)
This study tested the hypothesis that the increases in salivary and plasma [NO2−] after dietary NO3− supplementation would be greater when oral temperature and pH were independently elevated, and increased further when oral temperature and pH wer
Externí odkaz:
https://doaj.org/article/1fedcab78ccd4e7795a66d3332c37a07
Autor:
Mohammed Abu-Alghayth, Anni Vanhatalo, Lee J. Wylie, Sinead TJ. McDonagh, Christopher Thompson, Stefan Kadach, Paul Kerr, Miranda J. Smallwood, Andrew M. Jones, Paul G. Winyard
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 101974- (2021)
Ingested inorganic nitrate (NO3⁻) has multiple effects in the human body including vasodilation, inhibition of platelet aggregation, and improved skeletal muscle function. The functional effects of oral NO3⁻ involve the in vivo reduction of NO3
Externí odkaz:
https://doaj.org/article/ccca76cc967d449a8f90645b4e0a2df6
Autor:
Anni Vanhatalo, Joanna E. L'Heureux, James Kelly, Jamie R. Blackwell, Lee J. Wylie, Jonathan Fulford, Paul G. Winyard, David W. Williams, Mark van der Giezen, Andrew M. Jones
Publikováno v:
Redox Biology, Vol 41, Iss , Pp 101933- (2021)
Many oral bacteria reduce inorganic nitrate, a natural part of a vegetable-rich diet, into nitrite that acts as a precursor to nitric oxide, a regulator of vascular tone and neurotransmission. Aging is hallmarked by reduced nitric oxide production wi
Externí odkaz:
https://doaj.org/article/c66cc42ebd554799b16bb78a71f25c44
Autor:
Sotiris Kyriakou, Venetia Tragkola, Heba Alghol, Ioannis Anestopoulos, Tom Amery, Kyle Stewart, Paul G. Winyard, Dimitrios T. Trafalis, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 141 (2022)
Watercress is an enriched source of phenethyl isothiocyanate (PEITC), among other phytochemicals, with an antioxidant capacity. The aim of this study was to (i) chemically characterize and (ii) biologically evaluate the profile of the main health-pro
Externí odkaz:
https://doaj.org/article/cbf0416506534de384e72ca504df6d0d
Publikováno v:
Redox Biology, Vol 15, Iss C, Pp 34-40 (2018)
Graphene has a promising future in applications such as disease diagnosis, cancer therapy, drug/gene delivery, bio-imaging and antibacterial approaches owing to graphene's unique physical, chemical and mechanical properties alongside minimal toxicity
Externí odkaz:
https://doaj.org/article/c889f1e571f448038634e652a4b7296d