Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Paul G Anastasiades"'
Autor:
Filippo Ghezzi, Andre Marques-Smith, Paul G Anastasiades, Daniel Lyngholm, Cristiana Vagnoni, Alexandra Rowett, Gokul Parameswaran, Anna Hoerder-Suabedissen, Yasushi Nakagawa, Zoltan Molnar, Simon JB Butt
Publikováno v:
eLife, Vol 10 (2021)
Subplate neurons (SPNs) are thought to play a role in nascent sensory processing in neocortex. To better understand how heterogeneity within this population relates to emergent function, we investigated the synaptic connectivity of Lpar1-EGFP SPNs th
Externí odkaz:
https://doaj.org/article/c7d3e2030c9a4028b225ee22163067be
Autor:
Francesco Longo, Sameer Aryal, Paul G. Anastasiades, Marta Maltese, Corey Baimel, Federica Albanese, Joanna Tabor, Jeffrey D. Zhu, Mauricio M. Oliveira, Denise Gastaldo, Claudia Bagni, Emanuela Santini, Nicolas X. Tritsch, Adam G. Carter, Eric Klann
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112901- (2023)
Summary: Individuals with fragile X syndrome (FXS) are frequently diagnosed with autism spectrum disorder (ASD), including increased risk for restricted and repetitive behaviors (RRBs). Consistent with observations in humans, FXS model mice display d
Externí odkaz:
https://doaj.org/article/dc43b9ea499f4df290879ca6923d0caf
Publikováno v:
Cell Reports, Vol 22, Iss 3, Pp 679-692 (2018)
Excitation and inhibition are highly specific in the cortex, with distinct synaptic connections made onto subtypes of projection neurons. The functional consequences of this selective connectivity depend on both synaptic strength and the intrinsic pr
Externí odkaz:
https://doaj.org/article/51135f9d09994267b8496f6266ede41d
Autor:
Paul G. Anastasiades, Andre Marques-Smith, Daniel Lyngholm, Tom Lickiss, Sayda Raffiq, Dennis Kätzel, Gero Miesenböck, Simon J. B. Butt
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
GABAergic interneurons are key components of cortical circuits, yet their early connectivity is unknown. Here the authors show that during early postnatal development,Nkx2-1-derived interneurons engage in layer-specific and dynamic circuits, which ar
Externí odkaz:
https://doaj.org/article/eecafeca6fe24e208afc545e3bdbe8ed
Publikováno v:
Progress in Neurobiology. 218:102338
Modern life poses many threats to good-quality sleep, challenging brain health across the lifespan. Curtailed or fragmented sleep may be particularly damaging during adolescence, when sleep disruption by delayed chronotypes and societal pressures coi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4778b509aa67fb796f75a14f800da8
https://doi.org/10.1016/j.pneurobio.2022.102338
https://doi.org/10.1016/j.pneurobio.2022.102338
Autor:
Filippo Ghezzi, Andre Marques-Smith, Paul G Anastasiades, Daniel Lyngholm, Cristiana Vagnoni, Alexandra Rowett, Gokul Parameswaran, Anna Hoerder-Suabedissen, Yasushi Nakagawa, Zoltan Molnar, Simon JB Butt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63b62a81c1139b67e6fd81407a35ad94
https://doi.org/10.7554/elife.60810.sa2
https://doi.org/10.7554/elife.60810.sa2
Autor:
Anna Hoerder-Suabedissen, Yasushi Nakagawa, Andre Marques-Smith, Filippo Ghezzi, Zoltán Molnár, Alexandra Rowett, Simon J. B. Butt, Daniel Lyngholm, Gokul Parameswaran, Paul G. Anastasiades, Cristiana Vagnoni
Publikováno v:
eLife, Vol 10 (2021)
Ghezzi, F, Marques-Smith, A, Anastasiades, P G, Lyngholm, D, Vagnoni, C, Rowett, A, Parameswaran, G, Hoerder-Suabedissen, A, Nakagawa, Y, Molnar, Z & Butt, S J B 2021, ' Non-canonical role for Lpar1-EGFP subplate neurons in early postnatal mouse somatosensory cortex ', eLife, vol. 10, e60810 . https://doi.org/10.7554/eLife.60810
eLife
Ghezzi, F, Marques-Smith, A, Anastasiades, P G, Lyngholm, D, Vagnoni, C, Rowett, A, Parameswaran, G, Hoerder-Suabedissen, A, Nakagawa, Y, Molnar, Z & Butt, S J B 2021, ' Non-canonical role for Lpar1-EGFP subplate neurons in early postnatal mouse somatosensory cortex ', eLife, vol. 10, e60810 . https://doi.org/10.7554/eLife.60810
eLife
Subplate neurons (SPNs) are thought to play a role in nascent sensory processing in neocortex. To better understand how heterogeneity within this population relates to emergent function, we investigated the synaptic connectivity of Lpar1-EGFP SPNs th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9154a5386b8c29ca242c6975d50eab5
https://elifesciences.org/articles/60810
https://elifesciences.org/articles/60810
Autor:
Paul G. Anastasiades, David P. Collins
Publikováno v:
The Journal of Neuroscience. 39:2577-2580
The anterolateral motor cortex (ALM) and ventral medial (VM) thalamus are functionally linked to support persistent activity during motor planning. We analyzed the underlying synaptic interconnections using optogenetics and electrophysiology in mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed02506f2aacc005e8567d69865b200
https://doi.org/10.1523/jneurosci.2964-18.2019
https://doi.org/10.1523/jneurosci.2964-18.2019
Autor:
Paul G. Anastasiades, Adam G. Carter
Publikováno v:
Trends Neurosci
The prefrontal cortex (PFC) orchestrates higher brain function and becomes disrupted in many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous variety of projection neurons and interneurons. These cells are engaged by long-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c8eb81f9252fea64f28fc086f0127f
https://europepmc.org/articles/PMC8222144/
https://europepmc.org/articles/PMC8222144/
Publikováno v:
Neuron
Anastasiades, P G, Collins, D & Carter, A 2020, ' Mediodorsal and Ventromedial Thalamus Engage Distinct L1 Circuits in the Prefrontal Cortex ', Neuron, vol. 109, no. 2, pp. p314-330.E4 . https://doi.org/10.1016/j.neuron.2020.10.031
Anastasiades, P G, Collins, D & Carter, A 2020, ' Mediodorsal and Ventromedial Thalamus Engage Distinct L1 Circuits in the Prefrontal Cortex ', Neuron, vol. 109, no. 2, pp. p314-330.E4 . https://doi.org/10.1016/j.neuron.2020.10.031
Interactions between the thalamus and prefrontal cortex (PFC) play a critical role in cognitive function and arousal. Here, we use anatomical tracing, electrophysiology, optogenetics, and 2-photon Ca2+ imaging to determine how ventromedial (VM) and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2540874fc981d51d9c4a6e5c2ee5c9f0
https://europepmc.org/articles/PMC7855187/
https://europepmc.org/articles/PMC7855187/