Determinants of beat-to-beat variability of repolarization duration in the canine ventricular myocyte: a computational analysis.

Autor: Jordi Heijman, Antonio Zaza, Daniel M Johnson, Yoram Rudy, Ralf L M Peeters, Paul G A Volders, Ronald L Westra

Publikováno v: PLoS Computational Biology, Vol 9, Iss 8, p e1003202 (2013)

Beat-to-beat variability of repolarization duration (BVR) is an intrinsic characteristic of cardiac function and a better marker of proarrhythmia than repolarization prolongation alone. The ionic mechanisms underlying baseline BVR in physiological co

Externí odkaz: https://doaj.org/article/5b17bf03146049a39498d6762beb9c64

Understanding repolarization in the intracardiac unipolar electrogram: A long-lasting controversy revisited

Autor: Job Stoks, Laura R. Bear, Johan Vijgen, Paul Dendale, Ralf Peeters, Paul G. A. Volders, Matthijs J. M. Cluitmans

Publikováno v: Frontiers in Physiology, Vol 14 (2023)

Background: The optimal way to determine repolarization time (RT) from the intracardiac unipolar electrogram (UEG) has been a topic of debate for decades. RT is typically determined by either the Wyatt method or the “alternative method,” which bo

Externí odkaz: https://doaj.org/article/f46c07b99ae34f45b6e30f3c7409c721

Electromechanical reciprocity and arrhythmogenesis in long-QT syndrome and beyond

Autor: Katja E Odening, Henk J van der Linde, Michael J Ackerman, Paul G A Volders, Rachel M A ter Bekke

Publikováno v: Odening, Katja E; van der Linde, Henk J; Ackerman, Michael J; Volders, Paul G A; Ter Bekke, Rachel M A (2022). Electromechanical reciprocity and arrhythmogenesis in long-QT syndrome and beyond. European heart journal, 43(32), pp. 3018-3028. Oxford University Press 10.1093/eurheartj/ehac135

An abundance of literature describes physiological and pathological determinants of cardiac performance, building on the principles of excitation–contraction coupling. However, the mutual influencing of excitation–contraction and mechano-electric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855625bac5580dfd2e080419c16378ff
https://doi.org/10.1093/eurheartj/ehac135

Variant Location Is a Novel Risk Factor for Individuals With Arrhythmogenic Cardiomyopathy Due to a Desmoplakin (

Autor: Edgar T, Hoorntje, Charlotte, Burns, Luisa, Marsili, Ben, Corden, Victoria N, Parikh, Gerard J, Te Meerman, Belinda, Gray, Ahmet, Adiyaman, Richard D, Bagnall, Daniela Q C M, Barge-Schaapveld, Maarten P, van den Berg, Marianne, Bootsma, Laurens P, Bosman, Gemma, Correnti, Johan, Duflou, Ruben N, Eppinga, Diane, Fatkin, Michael, Fietz, Eric, Haan, Jan D H, Jongbloed, Arnaud D, Hauer, Lien, Lam, Freyja H M, van Lint, Amrit, Lota, Carlo, Marcelis, Hugh J, McCarthy, Anneke M, van Mil, Rogier A, Oldenburg, Nicholas, Pachter, R Nils, Planken, Chloe, Reuter, Christopher, Semsarian, Jasper J, van der Smagt, Tina, Thompson, Jitendra, Vohra, Paul G A, Volders, Jaap I, van Waning, Nicola, Whiffin, Arthur, van den Wijngaard, Ahmad S, Amin, Arthur A M, Wilde, Gijs, van Woerden, Laura, Yeates, Dominica, Zentner, Euan A, Ashley, Matthew T, Wheeler, James S, Ware, J Peter, van Tintelen, Jodie, Ingles

Publikováno v: Circulation. Genomic and precision medicine.

Truncating variants in desmoplakin (Individuals withThere were 98 probands and 72 family members (mean age at diagnosis 43±8 years, 59% women) with aIn the largest series of individuals with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7142023d0a2271d92d9519c93025ddd3
https://pubmed.ncbi.nlm.nih.gov/36580316

Sudden death by stress: how far under the nerves should we dig to find out why LQT1 patients die?

Autor: Peter J, Schwartz, Paul G A, Volders

Publikováno v: Journal of the American College of Cardiology. 63(8)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::03e66daff7aff4751a426c2d35f53576
https://pubmed.ncbi.nlm.nih.gov/24184248