Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Paul G, Furtmüller"'
Autor:
Hana Hanaee-Ahvaz, Monika Cserjan-Puschmann, Florian Mayer, Christopher Tauer, Bernd Albrecht, Paul G. Furtmüller, Birgit Wiltschi, Rainer Hahn, Gerald Striedner
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22463- (2023)
Functionalization of proteins by incorporating reactive non-canonical amino acids (ncAAs) has been widely applied for numerous biological and therapeutic applications. The requirement not to lose the intrinsic properties of these proteins is often un
Externí odkaz:
https://doaj.org/article/2f2ce037de7743439e4ad4c7f4ffdc74
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3933-3945 (2023)
The coproporphyrin dependent heme biosynthesis pathway is almost exclusively utilized by Gram-positive bacteria. This fact makes it a worthwhile topic for basic research, since a fundamental understanding of a metabolic pathway is necessary to transl
Externí odkaz:
https://doaj.org/article/ab02ec0ce2e047a6802aaf72e316ed4f
Publikováno v:
Biology, Vol 12, Iss 12, p 1527 (2023)
Coproporphyrinogen oxidase (CgoX) and protoporphyrinogen oxidase (PgoX) catalyze the oxidation of the flexible cyclic tetrapyrrole of porphyrinogen compounds into fully conjugated, planar macrocyclic porphyrin compounds during heme biosynthesis. Thes
Externí odkaz:
https://doaj.org/article/eff91766a6a64e459c2ac5fb67d6e5f1
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 23 (2023)
Human peroxidasin (PXDN) is a ubiquitous peroxidase enzyme expressed in most tissues in the body. PXDN represents an interesting therapeutic target for inhibition, as it plays a role in numerous pathologies, including cardiovascular disease, cancer a
Externí odkaz:
https://doaj.org/article/5e75727b80ff4cafb9eae7628dc27a7b
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 946 (2023)
Coproheme decarboxylases (ChdCs) are terminal enzymes of the coproporphyrin-dependent heme biosynthetic pathway. In this reaction, two propionate groups are cleaved from the redox-active iron-containing substrate, coproheme, to form vinyl groups of t
Externí odkaz:
https://doaj.org/article/d98dd22039d54f0aba0bed8c7716a430
Autor:
Daniel R. Ramos, Paul G. Furtmüller, Christian Obinger, Ángeles Peña-Gallego, Ignacio Pérez-Juste, J. Arturo Santaballa
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 303 (2023)
Electronic structure calculations using the density-functional theory (DFT) have been performed to analyse the effect of water molecules and protonation on the heme group of peroxidases in different redox (ferric, ferrous, compounds I and II) and spi
Externí odkaz:
https://doaj.org/article/8360308b68eb4e4c99615089eb75ac10
Autor:
Martina Paumann-Page, Nikolaus F. Kienzl, Jyoti Motwani, Boushra Bathish, Louise N. Paton, Nicholas J. Magon, Benjamin Sevcnikar, Paul G. Furtmüller, Michael W. Traxlmayr, Christian Obinger, Mike R. Eccles, Christine C. Winterbourn
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102090- (2021)
Peroxidasin, a heme peroxidase, has been shown to play a role in cancer progression. mRNA expression has been reported to be upregulated in metastatic melanoma cell lines and connected to the invasive phenotype, but little is known about how peroxida
Externí odkaz:
https://doaj.org/article/ecab46f1afd042139dc822be8320f965
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1529-1536 (2018)
There is an increasing interest in developing novel eosinophil peroxidase (EPO) inhibitors, in order to provide new treatment strategies against chronic inflammatory and neurodegenerative diseases caused by eosinophilic disorder. Within this study, a
Externí odkaz:
https://doaj.org/article/fbffca2cf5c94eb8b384f2e2d5caa111
Publikováno v:
Biomolecules; Volume 13; Issue 6; Pages: 946
Coproheme decarboxylases (ChdCs) are terminal enzymes of the coproporphyrin-dependent heme biosynthetic pathway. In this reaction, two propionate groups are cleaved from the redox-active iron-containing substrate, coproheme, to form vinyl groups of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::f76d9377296cc37518124f296c3897e3
Autor:
Jürgen Beck, Matthias Biechele, Christoph Repik, Petra Gruber, Paul G. Furtmüller, Rainer Hahn
Publikováno v:
Journal of Separation Science. 46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::068e4fa937b68692aa5ed227dc707d3d
https://doi.org/10.1002/jssc.202200943
https://doi.org/10.1002/jssc.202200943