Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Paul Fosbraey"'
Publikováno v:
Neuropharmacology. 40:279-288
We studied the role of striatal dopamine (DA) release in seizure activity evoked by the subcutaneous administration of the cholinesterase inhibitor pinacolyl methylphosphonofluoridate (soman), in the guinea-pig. The involvement of the dopamine recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0005074e316799c7829e1865db5a10d
https://doi.org/10.1016/s0028-3908(00)00136-2
https://doi.org/10.1016/s0028-3908(00)00136-2
Autor:
Paul Fosbraey, James A. Bourne
Publikováno v:
Journal of Neuroscience Methods. 99:85-90
This paper covers the design, development and operation of a novel piece of equipment, based around the CMA/12 guide probe (Carnegie Medicin, Sweden), which offers a low cost alternative for monitoring EEG at the site of microdialysis in a freely mov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02165b083257aefe7cc4467e1e024070
https://doi.org/10.1016/s0165-0270(00)00217-x
https://doi.org/10.1016/s0165-0270(00)00217-x
Publikováno v:
Neurochemistry International. 18:265-273
The protective effects of two dose regimes of the organophosphate pretreatment combination, physostigmine and hyoscine, were assessed on the central neurochemical changes produced following soman intoxication. The lower dose combination (physostigmin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a06835d3d583baf018c2d82347ae6f
https://doi.org/10.1016/0197-0186(91)90194-i
https://doi.org/10.1016/0197-0186(91)90194-i
Publikováno v:
European journal of pharmacology. 413(2-3)
We investigated the involvement of striatal dopamine release in electrographic and motor seizure activity evoked by kainic acid in the guinea pig. The involvement of the dopamine receptor subtypes was studied by systemic administration of the dopamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fdc905636ace4e861d13d8af325813
https://pubmed.ncbi.nlm.nih.gov/11226392
https://pubmed.ncbi.nlm.nih.gov/11226392
Publikováno v:
Brain research. 814(1-2)
There is evidence that acute exposure to kainic acid (KA) induces the release of endogenous ligands for opioid receptors and that μ-opioid agonists intensify KA-induced neurodegeneration. The aim of the present study was to investigate any acute tox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd15f344db544e936499e0411322665
https://pubmed.ncbi.nlm.nih.gov/9838030
https://pubmed.ncbi.nlm.nih.gov/9838030
Publikováno v:
Neuroscience research. 30(3)
Acute exposure to kainic acid (KA) induces neurochemical changes in dopaminergic systems in the brain and the aim of the present study was to investigate the acute toxicity of KA upon dopamine D2 receptors. Adult rats were injected intraperitoneally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ffa98411e8a226d3fe629c3a447d48a
https://pubmed.ncbi.nlm.nih.gov/9593330
https://pubmed.ncbi.nlm.nih.gov/9593330
Autor:
Gudrun Cassel, Paul Fosbraey
Publikováno v:
Journal of pharmacological and toxicological methods. 35(3)
In the present study, the technique of microdialysis combined with tandem high-performance liquid chromatography was used to determine the striatal levels of HI-6 and neurotransmitters following peripheral administration of HI-6 (50 mg/kg i.m.) in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36af3545eef368b7591551c040ced59b
https://pubmed.ncbi.nlm.nih.gov/8782094
https://pubmed.ncbi.nlm.nih.gov/8782094
Publikováno v:
Journal of neurochemistry. 54(1)
The effects of the organophosphate acetylcholinesterase (AChE) inhibitor soman (31.2 micrograms/kg s.c.) on guinea-pig brain AChE, transmitter, and metabolite levels were investigated. Concentrations of acetylcholine (ACh) and choline (Ch), noradrena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376c27ab03669444d2f235483e08e683
https://pubmed.ncbi.nlm.nih.gov/1967146
https://pubmed.ncbi.nlm.nih.gov/1967146
Publikováno v:
Journal of Neurochemistry. 53:1519-1526
Six brain areas of rats and guinea-pigs, killed by microwave irradiation, were used for the concomitant measurement of the levels and regional distribution of cholinergic, biogenic amine, and amino acid neurotransmitters and metabolites. Acetylcholin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dcd0d125500e91607cec03739bb738d
https://doi.org/10.1111/j.1471-4159.1989.tb08547.x
https://doi.org/10.1111/j.1471-4159.1989.tb08547.x
Publikováno v:
Journal of autonomic pharmacology. 1(1)
1 Activation of prejunctional muscarinic and opiate receptors on cholinergic neurones of the guinea-pig ileum by acetylcholine (ACh) or morphine was seen as an inhibition of twitch responses to transmural electrical stimulation. These inhibitory resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47272430768ba780b60d0bedb5397638
https://pubmed.ncbi.nlm.nih.gov/7341632
https://pubmed.ncbi.nlm.nih.gov/7341632