Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Paul F. Sauter"'
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Synthesis and Evaluation of Novel Ring‐Strained Noncanonical Amino Acids for Residue‐Specific Bioorthogonal Reactions in Living Cells
Autor: David W. Will, Nataliia V. Shymanska, Cécile Echalier, Christine Koehler, Christopher D. Reinkemeier, Paul F. Sauter, Edward A. Lemke, Carsten Schultz, Anna Rutkowska
Publikováno v: Chemistry – A European Journal
Chemistry (Weinheim an Der Bergstrasse, Germany)
Bioorthogonal reactions are ideally suited to selectively modify proteins in complex environments, even in vivo. Kinetics and product stability of these reactions are crucial parameters to evaluate their usefulness for specific applications. Strain p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d54b3cc6465af83c644b8926d335c35
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5
Genetic code expansion for multiprotein complex engineering
Autor: Juri Rappsilber, Martin Jechlinger, Zhuo Angel Chen, Hueseyin Besir, Attila Gyenesei, Mirella Wawryszyn, Kapil Gupta, Ksenija Radic, Juan Zou, Markus Hsi-Yang Fritz, Imre Berger, Jonathan J M Landry, Christine Koehler, Stefan Braese, Vladimir Benes, Paul F. Sauter, Peggy Stolt-Bergner, Piau Siong Tan, Jan O. Korbel, Sini Junttila, Edward A. Lemke, Gemma Estrada Girona, Bence Galik, Carsten Schultz, Jan Erik Hoffmann, Moritz Bosse Biskup, Giancarlo Pruneri
Publikováno v: Koehler, C, Sauter, P F, Wawryszyn, M, Girona, G E, Gupta, K, Landry, J J M, Fritz, M H Y, Radic, K, Hoffmann, J E, Chen, Z A, Zou, J, Tan, P S, Galik, B, Junttila, S, Stolt-Bergner, P, Pruneri, G, Gyenesei, A, Schultz, C, Biskup, M B, Besir, H, Benes, V, Rappsilber, J, Jechlinger, M, Korbel, J O, Berger, I, Braese, S & Lemke, E A 2016, ' Genetic code expansion for multiprotein complex engineering ', Nature Methods, vol. 13, no. 12, pp. 997-1000 . https://doi.org/10.1038/nmeth.4032
Koehler, C, Sauter, P F, Wawryszyn, M, Girona, G E, Gupta, K, Landry, J J M, Fritz, M H Y, Radic, K, Hoffmann, J E, Chen, Z A, Zou, J, Tan, P S, Galik, B, Junttila, S, Stolt-Bergner, P, Pruneri, G, Gyenesei, A, Schultz, C, Biskup, M B, Besir, H, Benes, V, Rappsilber, J, Jechlinger, M, Korbel, J O, Berger, I, Braese, S & Lemke, E A 2016, ' Genetic code expansion for multiprotein complex engineering ', Nature Methods, vol. 13, no. 12, pp. 997–1000 . https://doi.org/10.1038/nmeth.4032
We present a baculovirus-based protein engineering method that enables site-specific introduction of unique functionalities in a eukaryotic protein complex recombinantly produced in insect cells. We demonstrate the versatility of this efficient and r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2ba09e5ec8b2f696169ad003dea91a
https://hdl.handle.net/20.500.11820/d43a4262-d2fb-415b-82ab-e8dfb28a0add
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6
A Stereoselective Approach to Functionalized Cyclohexenones
Autor: Stefan Bräse, Anne C. Meister, Paul F. Sauter
Publikováno v: European Journal of Organic Chemistry. 2013:7110-7116
A catalytic enantioselective approach to 4-hydroxy-6-methylcyclohex-2-enones is presented herein. The stereogenic information is generated through a copper-catalyzed 1,4-addition to p-benzoquinone monoketal using a chiral, BINOL-based (BINOL = 1,1′
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fee690d705c0dd6e169f32b3e85d20ed
https://doi.org/10.1002/ejoc.201300752
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7
Chemical Synthesis of Glycosaminoglycans
Autor: Ute Schepers, Christin Bednarek, Mirella Wawryszyn, Marco Mende, Paul F. Sauter, Stefan Bräse, Moritz Bosse Biskup
Publikováno v: Chemical reviews. 116(14)
Glycosaminoglycans (GAGs) as one major part of the glycocalyx are involved in many essential biological cell processes, as well as in many courses of diseases. Because of the potential therapeutic application of GAG polymers, fragments, and also deri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e840469534f8b79da95396e1b00d3ad0
https://pubmed.ncbi.nlm.nih.gov/27410264
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8
Stereoselective synthesis of highly functionalized hydroindoles as building blocks for rostratins B-D and synthesis of the pentacyclic core of rostratin C
Autor: Paul F. Sauter, Sabilla Zhong, Martin Nieger, Stefan Bräse
Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany). 21(31)
The stereoselective synthesis of a variety of functionalized hydroindoles suitable as building blocks for thiodiketopiperazine natural products such as rostratins B-D is reported. The key precursor for all transformations is a previously reported hex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92e5aef35bf97d434c3c36fd1ff3545
https://pubmed.ncbi.nlm.nih.gov/26179956
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