Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Paul F. Robbins"'
Autor:
Gal Cafri, Rami Yossef, Anna Pasetto, Drew C. Deniger, Yong-Chen Lu, Maria Parkhurst, Jared J. Gartner, Li Jia, Satyajit Ray, Lien T. Ngo, Mohammad Jafferji, Abraham Sachs, Todd Prickett, Paul F. Robbins, Steven A. Rosenberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Adoptive cell therapy (ACT) using neoantigen-specific T cells can lead to tumor regression. Here the authors use an in vitro stimulation approach to isolate tumor specific memory T cells from peripheral blood of metastatic epithelial cancer patients
Externí odkaz:
https://doaj.org/article/4abe5b00b67f409c95fdd11f690fc2b9
Autor:
Yong Li, Steven A Rosenberg, Paul F Robbins, Zhiya Yu, Maria Parkhurst, Billel Gasmi, Nikolaos Zacharakis, Todd D Prickett, Jared J Gartner, Sri Krishna, Stephanie L Goff, Satyajit Ray, Frank J Lowery, Sivasish Sindiri, Alakesh Bera, Noam Levin, Sanghyun P Kim, Charles A Marquardt, Nolan R Vale, Lior Levy, Tiffany Benzine, Robert V Masi, Rafiqul Islam
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Tumor-infiltrating lymphocytes (TILs) targeting neoantigens can effectively treat a selected set of metastatic solid cancers. However, harnessing TILs for cancer treatments remains challenging because neoantigen-reactive T cells are often
Externí odkaz:
https://doaj.org/article/f685ba7746d3429ab6dd6d6e8a83fc10
Autor:
Nikolaos Zacharakis, Lutfi M. Huq, Samantha J. Seitter, Sanghyun P. Kim, Jared J. Gartner, Sivasish Sindiri, Victoria K. Hill, Yong F. Li, Biman C. Paria, Satyajit Ray, Billel Gasmi, Chyi-chia Lee, Todd D. Prickett, Maria R. Parkhurst, Paul F. Robbins, Michelle M. Langhan, Thomas E. Shelton, Anup Y. Parikh, Shoshana T. Levi, Jonathan M. Hernandez, Chuong D. Hoang, Richard M. Sherry, James C. Yang, Steven A. Feldman, Stephanie L. Goff, Steven A. Rosenberg
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(16)
PURPOSE Metastatic breast cancer (mBrCa) is most often an incurable disease with only modest responses to available immunotherapies. This study investigates the immunogenicity of somatic mutations in breast cancer and explores the therapeutic efficac
Autor:
Sanghyun P. Kim, Nolan R. Vale, Nikolaos Zacharakis, Sri Krishna, Zhiya Yu, Billel Gasmi, Jared J. Gartner, Sivasish Sindiri, Parisa Malekzadeh, Drew C. Deniger, Frank J. Lowery, Maria R. Parkhurst, Lien T. Ngo, Satyajit Ray, Yong F. Li, Victoria Hill, Maria Florentin, Robert V. Masi, Biman C. Paria, Noam Levin, Alakesh Bera, Elizabeth A. Hedges, Agnes Choi, Praveen D. Chatani, Anup Y. Parikh, Shoshana Levi, Samantha Seitter, Yong-Chen Lu, Zhili Zheng, Todd D. Prickett, Li Jia, Jonathan M. Hernandez, Chuong D. Hoang, Paul F. Robbins, Stephanie L. Goff, Richard M. Sherry, James C. Yang, Steven A. Rosenberg
Publikováno v:
Cancer Immunology Research. 10:932-946
Adoptive cellular therapy (ACT) targeting neoantigens can achieve durable clinical responses in patients with cancer. Most neoantigens arise from patient-specific mutations, requiring highly individualized treatments. To broaden the applicability of
Publikováno v:
Cancer Cell
Efforts to apply adoptive cell transfer (ACT) immunotherapy to patients with common epithelial cancers have been stimulated by the demonstration that the majority of these patients contain lymphocytes reactive against the expressed products of their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f5477366cfbde7ae193e3d9df303ea
https://europepmc.org/articles/PMC10184665/
https://europepmc.org/articles/PMC10184665/
Autor:
Steven A. Rosenberg, David S. Schrump, Isaac Kriley, Biman C. Paria, Scott Kivitz, Satyajit Ray, Todd Prickett, Thomas E. Shelton, Parisa Malekzadeh, Drew Deniger, Anna Pasetto, Jared J. Gartner, Li Jia, Yong-Chen Lu, Eric Tran, Paul F. Robbins, Maria Parkhurst, Winifred Lo
Supplementary Figure 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f59cb40fc83b120875be586c8356377
https://doi.org/10.1158/2326-6066.22542307.v1
https://doi.org/10.1158/2326-6066.22542307.v1
Autor:
Steven A. Rosenberg, David S. Schrump, Isaac Kriley, Biman C. Paria, Scott Kivitz, Satyajit Ray, Todd Prickett, Thomas E. Shelton, Parisa Malekzadeh, Drew Deniger, Anna Pasetto, Jared J. Gartner, Li Jia, Yong-Chen Lu, Eric Tran, Paul F. Robbins, Maria Parkhurst, Winifred Lo
Supplementary Tables 1 and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5243610ee0a82f1512c4fa8320bda478
https://doi.org/10.1158/2326-6066.22542295
https://doi.org/10.1158/2326-6066.22542295
Autor:
Steven A. Rosenberg, David S. Schrump, Isaac Kriley, Biman C. Paria, Scott Kivitz, Satyajit Ray, Todd Prickett, Thomas E. Shelton, Parisa Malekzadeh, Drew Deniger, Anna Pasetto, Jared J. Gartner, Li Jia, Yong-Chen Lu, Eric Tran, Paul F. Robbins, Maria Parkhurst, Winifred Lo
Supplementary Table 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb0d974fa256b6955c32f62e5ff3aeb
https://doi.org/10.1158/2326-6066.22542301
https://doi.org/10.1158/2326-6066.22542301
Autor:
Steven A. Rosenberg, James C. Yang, Richard M. Sherry, Stephanie L. Goff, Paul F. Robbins, Chuong D. Hoang, Jonathan M. Hernandez, Li Jia, Todd D. Prickett, Zhili Zheng, Yong-Chen Lu, Samantha Seitter, Shoshana Levi, Anup Y. Parikh, Praveen D. Chatani, Agnes Choi, Elizabeth A. Hedges, Alakesh Bera, Noam Levin, Biman C. Paria, Robert V. Masi, Maria Florentin, Victoria Hill, Yong F. Li, Satyajit Ray, Lien T. Ngo, Maria R. Parkhurst, Frank J. Lowery, Drew C. Deniger, Parisa Malekzadeh, Sivasish Sindiri, Jared J. Gartner, Billel Gasmi, Zhiya Yu, Sri Krishna, Nikolaos Zacharakis, Nolan R. Vale, Sanghyun P. Kim
Supplementary Figure from Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor–Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e3f8c006b4d5783eb104fc14a96821
https://doi.org/10.1158/2326-6066.22545620.v1
https://doi.org/10.1158/2326-6066.22545620.v1
Autor:
Steven A. Rosenberg, David S. Schrump, Isaac Kriley, Biman C. Paria, Scott Kivitz, Satyajit Ray, Todd Prickett, Thomas E. Shelton, Parisa Malekzadeh, Drew Deniger, Anna Pasetto, Jared J. Gartner, Li Jia, Yong-Chen Lu, Eric Tran, Paul F. Robbins, Maria Parkhurst, Winifred Lo
Adoptive cell therapy (ACT) with T cells targeting neoantigens can mediate durable responses in patients with metastatic cancer. Cell therapies targeting common shared antigens for epithelial cancers are not yet broadly available. Here, we report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822b2f7d9e39943192b97c1504a66ab5
https://doi.org/10.1158/2326-6066.c.6549862.v1
https://doi.org/10.1158/2326-6066.c.6549862.v1