Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Paul F. McDonagh"'
Autor:
Hussein N. Yassine, Grace Davis-Gorman, Craig S. Stump, Stephen S. Thomson, Justin Peterson, Paul F. McDonagh
Publikováno v:
International Journal of Endocrinology, Vol 2010 (2010)
Aspirin has lower antiplatelet activity in diabetic patients. Our aim is to study the roles of acute hyperglycemia and hyperlipidemia on aspirin function in diabetic subjects with and without cardiovascular disease. Using urine thromboxane (pg/mg cre
Externí odkaz:
https://doaj.org/article/1e3c0e50136247b89c2c808d45c7d81a
Autor:
Melissa Henry, Paul F. McDonagh, Jennifer B. Frye, Leslie S. Ritter, Janet L. Funk, Helena W. Morrison, Sierra Chandler, Lisa Davidson, Grace Davis-Gorman, Zoe Cohen
Publikováno v:
Microcirculation. 18:552-561
Please cite this paper as: Ritter, Davidson, Henry, Davis-Gorman, Morrison, Frye, Cohen, Chandler, McDonagh and Funk (2011). Exaggerated Neutrophil-Mediated Reperfusion Injury after Ischemic Stroke in a Rodent Model of Type 2 Diabetes. Microcirculati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a045e785027dbabc4b545f66739fde2
https://doi.org/10.1111/j.1549-8719.2011.00115.x
https://doi.org/10.1111/j.1549-8719.2011.00115.x
Autor:
Paul F. McDonagh, Helena W. Morrison, Jennifer B. Frye, Gregory L. Stahl, Leslie S. Ritter, Janet L. Funk, Grace Davis-Gorman
Publikováno v:
Current Neurovascular Research. 8:52-63
After complement system (CS) activation, the sequential production of complement products increases cell injury and death through opsonophagocytosis, cytolysis, adaptive, and inflammatory cell responses. These responses potentiate cerebral ischemia-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6101e321e7e85131a067fd65eae15a52
https://doi.org/10.2174/156720211794520260
https://doi.org/10.2174/156720211794520260
Publikováno v:
Diabetes Research and Clinical Practice. 84:11-18
Type 2 diabetes in humans is associated with hypercoaguability; however, little is known about platelet function in mouse models of type 2 diabetes used to study this disorder. Therefore, the purpose of this study was to examine platelet aggregation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712aa79aaeb6c235497cdf99553fee47
https://doi.org/10.1016/j.diabres.2009.01.011
https://doi.org/10.1016/j.diabres.2009.01.011
Autor:
Norma Seaver, Paul F. McDonagh, Garrett S. Pacheco, Alexandre Le Guyader, Jack G. Copeland, Grace Davis-Gorman
Publikováno v:
Journal of Diabetes and its Complications. 23:65-70
Increased aspirin resistance may contribute to the increase in thrombotic events observed in patients with type 2 diabetes. In this study, we examined if acute exposure to increased plasma glucose impaired the inhibitory effects of aspirin on platele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70fe74e5330aaace824c1e11d058659
https://doi.org/10.1016/j.jdiacomp.2007.06.003
https://doi.org/10.1016/j.jdiacomp.2007.06.003
Publikováno v:
Blood Coagulation & Fibrinolysis. 19:305-309
The role of caspases in platelet function is not well understood. When platelets are activated, they express phosphatidylserine on the outer plasma membrane, form platelet microparticles, and aggregate (Pag). The aims of this study were to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ada0b7d3ceacd8360e5ab0308a5efb
https://doi.org/10.1097/mbc.0b013e3283001cf5
https://doi.org/10.1097/mbc.0b013e3283001cf5
Publikováno v:
Biological Research For Nursing. 6:281-288
Ischemic stroke and reperfusion (ISR) is associated with an inflammatory response characterized, in part, by the formation of leukocyte-platelet aggregates (LPA). Aggregate formation may amplify the immunologic and hemostatic functions of both cell t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae486b7d3346a843d818d11decba364
https://doi.org/10.1177/1099800405274579
https://doi.org/10.1177/1099800405274579
Publikováno v:
Thrombosis Research. 113:387-393
Apoptosis of nucleated cells is regulated by caspases, a group of cysteine proteases, and is characterized by phosphatidylserine expression on the outer leaflet of the plasma membrane. Reports indicate that platelets contain caspases. However, the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf7b6f71417d7c43247ffe5e36eda1b9
https://doi.org/10.1016/j.thromres.2004.03.020
https://doi.org/10.1016/j.thromres.2004.03.020