Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Paul F. Lang"'
Autor:
Paul F. Lang, Yassmine Chebaro, Xiaoyue Zheng, John A. P. Sekar, Bilal Shaikh, Darren A. Natale, Jonathan R. Karr
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-21 (2020)
Abstract Non-canonical residues, caps, crosslinks, and nicks are important to many functions of DNAs, RNAs, proteins, and complexes. However, we do not fully understand how networks of such non-canonical macromolecules generate behavior. One barrier
Externí odkaz:
https://doaj.org/article/22daf2cdfc72467e9f4ac79ddb1bcf89
The mammalian cell cycle is regulated by a well-studied but complex biochemical reaction system. Computational models provide a particularly systematic and systemic description of the mechanisms governing mammalian cell cycle control. By combining bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b5298db5c8f0743409412f51928ce3b
https://doi.org/10.1101/2023.05.04.539349
https://doi.org/10.1101/2023.05.04.539349
Publikováno v:
ACS Synthetic Biology, 9 (11)
ACS Synthetic Biology
ACS Synthetic Biology
Synthetic biology relies on rapid and efficient methods to stably integrate DNA payloads encoding for synthetic biological systems into the genome of living cells. The size of designed biological systems increases with their complexity, and novel met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de45830e50ef810c4e5876efc035eee
https://doi.org/10.1021/acssynbio.0c00413
https://doi.org/10.1021/acssynbio.0c00413
Reserve Flux Capacity in the Pentose Phosphate Pathway by NADPH Binding Is Conserved across Kingdoms
Autor:
Andreas Kuehne, Tobias Fuhrer, Alexandra Estermann, Paul F. Lang, Dimitris Christodoulou, Uwe Sauer
Publikováno v:
iScience, Vol 19, Iss, Pp 1133-1144 (2019)
iScience, 19
iScience
iScience, 19
iScience
Summary All organisms evolved defense mechanisms to counteract oxidative stress and buildup of reactive oxygen species (ROS). To test whether a potentially conserved mechanism exists for the rapid response, we investigated immediate metabolic dynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f26eeb2f9fb2f75673de7a620670c2
http://www.sciencedirect.com/science/article/pii/S2589004219303256
http://www.sciencedirect.com/science/article/pii/S2589004219303256
Autor:
Tony Ly, Adrijana Crncec, Chris Bakal, Maria F. Suarez Peredo Rodriguez, Paul F. Lang, Bela Novak, Oliver Busby, Nadia Hégarat, Fabio Echegaray Iturra, Alexis R. Barr, Helfrid Hochegger, Masato T. Kanemaki, Yan Gu, Angus I. Lamond
Publikováno v:
The EMBO Journal
Two mitotic cyclin types, cyclin A and B, exist in higher eukaryotes, but their specialised functions in mitosis are incompletely understood. Using degron tags for rapid inducible protein removal, we analyse how acute depletion of these proteins affe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f39d453c0a32cf622e2b79ec8e228d2
https://doi.org/10.15252/embj.2020104419
https://doi.org/10.15252/embj.2020104419
Autor:
John A. P. Sekar, Paul F. Lang, Yassmine Chebaro, Darren A. Natale, Jonathan R. Karr, Xiaoyue Zheng, Bilal Shaikh
Publikováno v:
Genome Biology
Genome Biology, 2020, 21 (1), ⟨10.1186/s13059-020-02025-z⟩
Genome Biology, Vol 21, Iss 1, Pp 1-21 (2020)
Genome Biology, 2020, 21 (1), ⟨10.1186/s13059-020-02025-z⟩
Genome Biology, Vol 21, Iss 1, Pp 1-21 (2020)
Non-canonical residues, caps, crosslinks, and nicks are important to many functions of DNAs, RNAs, proteins, and complexes. However, we do not fully understand how networks of such non-canonical macromolecules generate behavior. One barrier is our li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a82a1ff42dc8303af499f64fbaedb5
https://doi.org/10.1186/s13059-020-02025-z
https://doi.org/10.1186/s13059-020-02025-z
Autor:
Chris Bakal, Helfrid Hochegger, Crncec A, Paul F. Lang, Bela Novak, Yan Gu, Tony Ly, Masato T. Kanemaki, Nadia Hégarat, Alexis R. Barr, Peredoa Rodri-guez Mfs, Fabio Echegaray Iturra, Angus I. Lamond
Two mitotic Cyclins, A and B, exist in higher eukaryotes, but their specialised functions in mitosis are poorly understood. Using degron tags we analyse how acute depletion of these proteins affects mitosis. Loss of Cyclin A in G2-phase prevents the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880cd3506377faafe1eb9d4cd9463069
Autor:
Paul F. Lang, Steen Larsen, Anne-Kristine Meinild-Lundby, Stefanie Keiser, Andreas Breenfeldt Andersen, Carsten Lundby, Paul Robach, Sune Dandanell, Laura Oberholzer, Bent R. Rønnestad
Publikováno v:
Scandinavian journal of medicinescience in sports. 28(12)
Elite endurance athletes possess a high capacity for whole-body maximal fat oxidation (MFO). The aim was to investigate the determinants of a high MFO in endurance athletes. The hypotheses were that augmented MFO in endurance athletes is related to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30c833dd8dca33aed7b6dc4034d8e65
https://pubmed.ncbi.nlm.nih.gov/30218613
https://pubmed.ncbi.nlm.nih.gov/30218613
Autor:
Michael E. Baumgartner, Paul F. Langton, Remi Logeay, Alex Mastrogiannopoulos, Anna Nilsson-Takeuchi, Iwo Kucinski, Jules Lavalou, Eugenia Piddini
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Investigating organ biology often requires methodologies to induce genetically distinct clones within a living tissue. However, the 3D nature of clones makes sample image analysis challenging and slow, limiting the amount of information that
Externí odkaz:
https://doaj.org/article/b431140ebdbd4b4b8ccb044fce0d375a
Autor:
Kai-Uwe Fröhlich, Paul F. Lang
Based upon a comprehensive analysis of current literature and by combining a molecular biology and a sports science perspective, this review examines (1) if a correlation between physical activity load and telomere length (TL) exists, and (2) compreh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2791dcd7d76bba4bc99e4a6e68edc1