Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Paul F. Gulyassy"'
Autor:
Paul F. Gulyassy
Publikováno v:
Seminars in Dialysis. 7:232-235
Publikováno v:
ASAIO Journal. 39:M569-M572
Major advances in dialysis therapy have occurred over the last decade, yet various abnormalities persist in end-stage renal disease (ESRD) patients. The etiology of these residual defects remains largely unknown. We are currently testing the hypothes
Autor:
PAUL F. GULYASSY
Publikováno v:
ASAIO Journal. 40:92-94
Autor:
Paul F. Gulyassy, Thomas A. Depner
Publikováno v:
American Journal of Kidney Diseases. 2:578-601
Publikováno v:
Clinical Chemistry. 32:938-942
Using our newly developed ion-pairing reversed-phase liquid-chromatographic method for assay of indoxyl sulfate, we measured its concentration in plasma of normal subjects and patients in various degrees of renal failure. Response was linear over the
Publikováno v:
Nephron. 25:231-237
Phenytoin binding to uremic plasma was studied in vitro. Inhibition of binding independent of albumin concentration was demonstrated. Acidification from pH 8 to pH 3 produced a small decrease in binding by normal plasma but no change or a small incre
Autor:
Gary R. Burke, Paul F. Gulyassy
Publikováno v:
Medical Clinics of North America. 63:1191-1203
Publikováno v:
Kidney International. 6(4):222-229
Reduced in vitro binding of tryptophan by plasma in uremia. Since markedly depressed binding of the essential amino acid tryptophan to plasma proteins of fasting chronically uremic patients was previously shown, we have now determined the association
Publikováno v:
Biochemical Pharmacology. 34:2431-2438
Decreased binding of aromatic acidic drugs and endogenous metabolites to plasma proteins of patients with severe renal failure appears to be due to accumulation of unknown solutes. Both the warfarin and indole binding sites of albumin, the principal
Publikováno v:
Scopus-Elsevier
We have developed a high-performance liquid chromatography (HPLC) method for assay of hippurate in plasma of patients with renal failure. Hippurate accounts, in part, for the impaired binding of drugs and metabolites to albumin and may cause other di