Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Paul F, Terranova"'
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 33:456-463
Objectives Prostate cancers are the frequently diagnosed cancers in men, and patients with metastatic disease only have 28% chance for 5-year survival. Patients with low-risk tumors are subjected to active surveillance, whereas high-risk cases are ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40347f0e54909f801a32d709330aa943
https://doi.org/10.1016/j.urolonc.2015.05.006
https://doi.org/10.1016/j.urolonc.2015.05.006
Autor:
Paul F. Terranova
Menopause is a condition in women whereby reduced ovarian function accompanied by declining levels of estrogen in circulation lead to cessation of menstrual cycles and increases the risk for hot flashes, osteoporosis, cardiovascular disease, sleep di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13b35b3df7df2bfa8b0e5cfbf8145ea9
https://doi.org/10.1016/b978-0-12-801238-3.04972-2
https://doi.org/10.1016/b978-0-12-801238-3.04972-2
Publikováno v:
Endocrinology. 151:3407-3419
TNFalpha is an inflammatory-related cytokine that has inhibitory effects on gonadotropin- and cAMP-stimulated steroidogenesis and folliculogenesis. Because ovulation is an inflammatory reaction and TNF specifically induces serum amyloid A3 (SAA3) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c50cda532d88101a3208c23ee39ba1e
https://doi.org/10.1210/en.2009-1321
https://doi.org/10.1210/en.2009-1321
Publikováno v:
Molecular and Cellular Biochemistry. 318:191-200
In order to evaluate the role of Src tyrosine kinase in thecal cell steroidogenesis, a pharmacological approach was utilized by treating enriched populations of mouse ovarian theca-interstitial cells in vitro with a direct Src kinase inhibitor, PP2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6e23b475dc9b1793351707fb9f50c9
https://doi.org/10.1007/s11010-008-9871-9
https://doi.org/10.1007/s11010-008-9871-9
Autor:
Paul F. Terranova, Aijing Sun, Jiawu Song, Benyi Li, Stan Svojanovsky, Jianxi Tang, J. Brantley Thrasher, Hong Gang Wang, Yan Hong
Publikováno v:
The Prostate. 68:453-461
Background Recently we reported that silencing the androgen receptor (AR) gene reduced Bcl-xL expression that was associated with a profound apoptotic cell death in prostate cancer cells. In this study we further investigated AR-regulated Bcl-xL expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00062a3f48ab62432da940c5acafe0de
https://doi.org/10.1002/pros.20723
https://doi.org/10.1002/pros.20723
Autor:
Jodi A. Flaws, Paul F. Terranova, Kimberly R. Barnett, Katherine F. Roby, Dragana Tomic, Janice K. Babus, Rupesh K. Gupta
Publikováno v:
Toxicology and Applied Pharmacology. 223:66-72
The aryl hydrocarbon receptor (AHR) mediates the toxicity of a variety of environmental chemicals. Although little is known about the physiological role of the AHR, studies suggest that it plays an important role in regulating ovulation because Ahr d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841df9f0983c95bd7fbfd5cf25bc040b
https://doi.org/10.1016/j.taap.2007.05.014
https://doi.org/10.1016/j.taap.2007.05.014
Autor:
Christopher M. Schneider, Kristian W. Fried, Apurba Datta, Karl-Werner Schramm, Antonius Kettrup, Paul F. Terranova, Dieter Lenoir, Douglas R. Powell, Claudia Corsten, Karl K. Rozman, Naima Chahbane, Gunda I. Georg
Publikováno v:
ChemMedChem. 2:890-897
Polychlorinated dibenzo-p-dioxins are persistent environmental pollutants. The most potent congener, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), causes a wasting syndrome and is a potent carcinogen and immunosuppressant in the rat at high doses. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e555f300b61bcafa6e98b2e2473a277f
https://doi.org/10.1002/cmdc.200700005
https://doi.org/10.1002/cmdc.200700005
Autor:
Janice K. Babus, Chuck R. Greenfeld, Melissa E. Pepling, Katherine F. Roby, Paul F. Terranova, Jodi A. Flaws
Publikováno v:
Biology of Reproduction. 76:224-231
It is believed that a finite pool of primordial follicles is established during embryonic and neonatal life. At birth, the mouse ovary consists of clusters of interconnected oocytes surrounded by pregranulosa cells. Shortly after birth these structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::058914a98c635595d6acbb256e15732c
https://doi.org/10.1095/biolreprod.106.055509
https://doi.org/10.1095/biolreprod.106.055509
Publikováno v:
Endocrine. 27:017-024
TNF is known to suppress gonadotropin-induced steroid secretion by Leydig cells. However, the mechanisms by which this occurs are largely unknown. Because expression of many steroidogenic proteins is regulated by the PKA pathway, effects of TNF on CR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ab483f8cfe403cedcebd2a1a27502d
https://doi.org/10.1385/endo:27:1:017
https://doi.org/10.1385/endo:27:1:017
Publikováno v:
Endocrinology. 145:2245-2252
TNF-alpha has significant inhibitory effects on steroidogenesis and folliculogenesis and is associated with several inflammatory responses. Because ovulation is an inflammatory reaction, the effects of TNF on the family of acute-phase proteins in gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca28307c788f54e16402acf7cad2339
https://doi.org/10.1210/en.2003-1261
https://doi.org/10.1210/en.2003-1261