Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Paul E. Young"'
Autor:
Helen McCormick, Paul E. Young, Suzy S. J. Hur, Keith Booher, Hunter Chung, Jennifer E. Cropley, Eleni Giannoulatou, Catherine M. Suter
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract Background Cytosine methylation is a stable epigenetic modification of DNA that plays an important role in both normal physiology and disease. Most diseases exhibit some degree of sexual dimorphism, but the extent to which epigenetic states
Externí odkaz:
https://doaj.org/article/7f67c190e1204a23b8ae2664e28938e1
Autor:
Jennifer E. Cropley, Sally A. Eaton, Alastair Aiken, Paul E. Young, Eleni Giannoulatou, Joshua W.K. Ho, Michael E. Buckland, Simon P. Keam, Gyorgy Hutvagner, David T. Humphreys, Katherine G. Langley, Darren C. Henstridge, David I.K. Martin, Mark A. Febbraio, Catherine M. Suter
Publikováno v:
Molecular Metabolism, Vol 5, Iss 8, Pp 699-708 (2016)
Objective: Parental obesity can induce metabolic phenotypes in offspring independent of the inherited DNA sequence. Here we asked whether such non-genetic acquired metabolic traits can be passed on to a second generation that has never been exposed t
Externí odkaz:
https://doaj.org/article/e750315967c34129a01c1104d440a993
Autor:
Amy M. Nicks, Sara R. Holman, Andrea Y. Chan, Michael Tsang, Paul E. Young, David T. Humphreys, Nawazish Naqvi, Ahsan Husain, Ming Li, Nicola J. Smith, Siiri E. Iismaa, Robert M. Graham
Publikováno v:
Journal of molecular and cellular cardiology. 170
Primary cardiomyocytes are invaluable for understanding postnatal heart development. However, a universal method to obtain freshly purified cardiomyocytes without using different age-dependent isolation procedures and cell culture, is lacking. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d772a1e215fa06fd61c129374d5dbd17
https://pubmed.ncbi.nlm.nih.gov/35644482
https://pubmed.ncbi.nlm.nih.gov/35644482
Publikováno v:
International Journal of Surgical Pathology. :106689692211368
Peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS) is a relatively rare mature T-cell lymphoma that cannot be categorized under any of the well-defined category. This type of aggressive lymphoma mostly involves the lymph nodes, though an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6087e295fa58b77eba516357d2f56704
https://doi.org/10.1177/10668969221136894
https://doi.org/10.1177/10668969221136894
Autor:
Andrea Y. Chan, Sara R. Holman, Ahsan Husain, Paul E. Young, Nicola J. Smith, Siiri E. Iismaa, Ming Li, Robert M. Graham, Nawazish Naqvi, Michael Tsang, David T. Humphreys, Amy M Nicks
Rationale: Primary cardiomyocytes are invaluable for understanding postnatal heart development and elucidating disease mechanisms in genetic and pharmacological models, however, a method to obtain freshly purified cardiomyocytes at any postnatal age,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82f7c595c5885a7569c9a86ca9c41151
https://doi.org/10.1101/2021.09.30.462562
https://doi.org/10.1101/2021.09.30.462562
Autor:
Kitty Lo, Andrew F. Hill, Boris Yagound, Benjamin P. Oldroyd, Alyson Ashe, Gabriele Buchmann, Owen T. Watson, Emily J. Remnant, Paul E. Young, Mitch Shambrook
Polyandrous social insects such as the honey bee are prime candidates for parental manipulation of gene expression in offspring. Although there is good evidence for parent-of-origin effects in honey bees the epigenetic mechanisms that underlie these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e696db5b53612b6802c7a3f63fb6b184
https://doi.org/10.1101/2021.08.27.457896
https://doi.org/10.1101/2021.08.27.457896
Autor:
Paul E. Young, L. Jeffrey Medeiros
Publikováno v:
Blood. 139(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d7c542e9f702065373f849117171f0
https://pubmed.ncbi.nlm.nih.gov/34989768
https://pubmed.ncbi.nlm.nih.gov/34989768
Autor:
Jessica Farr, Monique J. Windley, Chai Ann Ng, Adam P. Hill, Paul E. Young, Matthew D. Perry, Jamie I. Vandenberg
KCNH2is one of the 59 medically actionable genes recommended by the American College of Medical Genetics for reporting of incidental findings from clinical genomic sequencing. However, half of the reportedKCNH2variants in the ClinVar database are cla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f794c42355fe43c8641a03e9dd4efd9f
https://doi.org/10.1101/2021.02.02.427891
https://doi.org/10.1101/2021.02.02.427891
Autor:
Paul E. Young, Jessica Farr, Chai Ann Ng, Jamie I. Vandenberg, Monique J. Windley, Matthew D. Perry, Adam P. Hill
Publikováno v:
Biology Methods and Protocols. 6
KCNH2 is one of the 59 medically actionable genes recommended by the American College of Medical Genetics for reporting of incidental findings from clinical genomic sequencing. However, half of the reported KCNH2 variants in the ClinVar database are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b43f9c3de6b27c037c3aba46b034a47
https://doi.org/10.1093/biomethods/bpab003
https://doi.org/10.1093/biomethods/bpab003
Management of chronic pain with opioids is a common practice. Because of the addictive potential of these medications, strict monitoring to ensure compliance is enforced, including routine urine drug tests. Prior to prescribing opioids, medications a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a27460143def191cb742f1ba5a91f97f
https://doi.org/10.1016/b978-0-12-815846-3.00073-9
https://doi.org/10.1016/b978-0-12-815846-3.00073-9