Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Paul E. O'Brien"'
Autor:
Arthe Raajendiran, Geraldine Ooi, Jackie Bayliss, Paul E. O’Brien, Ralf B. Schittenhelm, Ashlee K. Clark, Renea A. Taylor, Matthew S. Rodeheffer, Paul R. Burton, Matthew J. Watt
Publikováno v:
Cell Reports, Vol 27, Iss 5, Pp 1528-1540.e7 (2019)
Summary: Adipocyte progenitor cells (APCs) provide the reservoir of regenerative cells to produce new adipocytes, although their identity in humans remains elusive. Using FACS analysis, gene expression profiling, and metabolic and proteomic analyses,
Externí odkaz:
https://doaj.org/article/20f296ab02ac4555afaf35da238c3207
Autor:
Qi Yang Damien Qi, Julie Playfair, Wendy A. Brown, Paul Burton, Paul E. O'Brien, John M. Wentworth
Publikováno v:
Diabetes, Obesity and Metabolism. 25:1464-1472
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03cdb3377d0b86d3b5638d540e02a5a9
https://doi.org/10.1111/dom.14992
https://doi.org/10.1111/dom.14992
Autor:
J. Silvio Gutkind, Eva Szabo, Carter Van Waes, Scott M. Lippman, Alfredo A. Molinolo, Olivier Harismendy, Xingyu Wu, Zhiyong Wang, Juan Luis Callejas-Varela, Lynn Vitale-Cross, Daniel Martin, Julie A. Vick, Anvesh Kompelli, Amit J. Sood, Kristina Godwin, Maria Gisele Matheus, Paul E. O'Brien, Keisuke Shirai, Terry A. Day
Purpose:We studied the impact of mTOR signaling inhibition with rapamycin in head and neck squamous cell carcinoma (HNSCC) in the neoadjuvant setting. The goals were to evaluate the mTOR pathway as a therapeutic target for patients with advanced HNSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07475590e6fc7e15c07867f9fe6a45b1
https://doi.org/10.1158/1078-0432.c.6526884.v1
https://doi.org/10.1158/1078-0432.c.6526884.v1
Autor:
J. Silvio Gutkind, Eva Szabo, Carter Van Waes, Scott M. Lippman, Alfredo A. Molinolo, Olivier Harismendy, Xingyu Wu, Zhiyong Wang, Juan Luis Callejas-Varela, Lynn Vitale-Cross, Daniel Martin, Julie A. Vick, Anvesh Kompelli, Amit J. Sood, Kristina Godwin, Maria Gisele Matheus, Paul E. O'Brien, Keisuke Shirai, Terry A. Day
Supplemental Materials and Figures Supplemental Figure 1. Trial design. A single-arm, open-label, interventional, neoadjuvant clinical trial design was used for our study. At the indicated days patients were screened, and laboratory tests, physical e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3fb158ec0f63c32f8f3f4ae9bd767f
https://doi.org/10.1158/1078-0432.22468278.v1
https://doi.org/10.1158/1078-0432.22468278.v1
Autor:
Paul E. O'Brien
Publikováno v:
The Lancet Diabetes & Endocrinology. 7:889-891
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6203bf07be4988b38d7636254f1d01
https://doi.org/10.1016/s2213-8587(19)30352-3
https://doi.org/10.1016/s2213-8587(19)30352-3
Autor:
Paul E. O'Brien, Renea A. Taylor, Ralf B. Schittenhelm, Jackie Bayliss, Matthew J. Watt, Paul Burton, Arthe Raajendiran, Ashlee K. Clark, Matthew S. Rodeheffer, Geraldine J. Ooi
Publikováno v:
Cell Reports, Vol 27, Iss 5, Pp 1528-1540.e7 (2019)
Summary: Adipocyte progenitor cells (APCs) provide the reservoir of regenerative cells to produce new adipocytes, although their identity in humans remains elusive. Using FACS analysis, gene expression profiling, and metabolic and proteomic analyses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdccfeaaa3599236a94829d9b669e85d
http://www.sciencedirect.com/science/article/pii/S2211124719304656
http://www.sciencedirect.com/science/article/pii/S2211124719304656
Autor:
Paul Burton, Cheryl Laurie, Wendy A. Brown, Ken Sikaris, Carel W. le Roux, Lisa Doyle, John M. Wentworth, Geraldine J. Ooi, Arul Earnest, Paul E. O'Brien
Publikováno v:
Obesity Surgery. 28:1351-1362
Dyslipidemia affects up to 75% of morbidly obese individuals and is a key driver of cardiovascular disease. Weight loss is an established strategy to improve metabolic risk, including dyslipidemia. We aimed to determine weight loss goals for resoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9ffa279da5dfbef2c2ea655ab9b19b
https://doi.org/10.1007/s11695-017-3015-9
https://doi.org/10.1007/s11695-017-3015-9
Autor:
Leonard C. Harrison, Gaetano Naselli, Paul E. O'Brien, Gordon K. Smyth, Matthew E. Ritchie, Jian-Guo Zhang, Esther Bandala-Sanchez, John M. Wentworth, Ruijie Liu
Publikováno v:
International Journal of Obesity. 41:1782-1789
Inflammatory factors derived from adipose tissue have been implicated in mediating insulin resistance in obesity. We sought to identify these using explanted human adipose tissue exposed to innate and adaptive immune stimuli.Subcutaneous and omental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6160a5028f59817fe86f6d2d4c942b0
https://doi.org/10.1038/ijo.2017.180
https://doi.org/10.1038/ijo.2017.180
Autor:
Cheryl Laurie, Peter Nottle, Geraldine J. Ooi, Paul E. O'Brien, Geoff Hebbard, Andrew Smith, Richard Yao-Yen Chen, Gary Crosthwaite, Wendy A. Brown, Paul Burton
Publikováno v:
Obesity Surgery. 27:2434-2443
The effect of the laparoscopic adjustable gastric band (LAGB) on esophageal acid exposure and reflux is poorly understood. Optimal technique and normative values for acid exposure have not been established in this group. High-resolution manometry (HR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7628a8efd510228b96e9109b6aea650
https://doi.org/10.1007/s11695-017-2662-1
https://doi.org/10.1007/s11695-017-2662-1
Autor:
Paul Burton, Andrew L. Smith, Wendy A. Brown, Stewart Skinner, Gary Crosthwaite, Annemarie Hindle, Paul E. O'Brien, Leah Brennan
Publikováno v:
Obesity Surgery
Introduction: Durability is a key requirement for the broad acceptance of bariatric surgery. We report on durability at and beyond 10 years with a systematic review and meta-analysis of all reports providing data at 10 or more years and a single-cent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2823151c64002fde6985c8b6ae963a9
https://acuresearchbank.acu.edu.au/item/8v886/long-term-outcomes-after-bariatric-surgery-a-systematic-review-and-meta-analysis-of-weight-loss-at-10-or-more-years-for-all-bariatric-procedures-and-a-single-centre-review-of-20-year-outcomes-after
https://acuresearchbank.acu.edu.au/item/8v886/long-term-outcomes-after-bariatric-surgery-a-systematic-review-and-meta-analysis-of-weight-loss-at-10-or-more-years-for-all-bariatric-procedures-and-a-single-centre-review-of-20-year-outcomes-after