Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Paul E. C. Brenchley"'
Autor:
Andrea Luengas-Martinez, Anna Kamaly-Asl, Iskander H Chaudhry, Paul E C Brenchley, Helen S Young
Publikováno v:
Clinical and Experimental Dermatology. 48:181-187
BackgroundVascular dysfunction is a significant contributor to the pathophysiology of psoriasis. Some individuals have variation within the gene for vascular endothelial growth factor-A (VEGF-A), which confers an increased risk of developing psoriasi
Autor:
Suzanne C Simmons, Hannaleena Jämsä, Dilson Silva, Celia M Cortez, Edward A McKenzie, Carolina C Bitu, Sirpa Salo, Sini Nurmenniemi, Pia Nyberg, Juha Risteli, Carlos E B deAlmeida, Paul E C Brenchley, Tuula Salo, Sotiris Missailidis
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e96846 (2014)
Heparanase is an endoglycosidase enzyme present in activated leucocytes, mast cells, placental tissue, neutrophils and macrophages, and is involved in tumour metastasis and tissue invasion. It presents a potential target for cancer therapies and vari
Externí odkaz:
https://doaj.org/article/9a0caa1e6dee4b349abf043f3d7163b4
Publikováno v:
Transplantation. 57:1727-1731
Autor:
Shelley, Harris, Beatrice M, Coupes, Stephen A, Roberts, Ian S D, Roberts, Colin D, Short, Paul E C, Brenchley
Publikováno v:
Journal of nephrology. 20(2)
Evidence from experimental models and clinical studies supports a major role for transforming growth factor-beta1 (TGF-beta1) in renal fibrosis. The aim of this study was to use repeated measurement of plasma TGF-beta1 as an indicator of persistent e
Autor:
Tibor J, Kovács, Shelley, Harris, Tibor K, Vas, Ildikó, Seres, Colin D, Short, István K, Wittmann, György, Paragh, Michael I, Mackness, Bharti, Mackness, Paul N, Durrington, Judit M, Nagy, Paul E C, Brenchley
Publikováno v:
Journal of nephrology. 19(6)
HDL-associated paraoxonase (PON1) reduces oxidation of lipids in LDL, and activity is inversely related to coronary heart disease risk with a beneficial effect on the development of atherosclerosis. Risk factors associated with atherosclerosis, such
Autor:
Angela M, Summers, Paul E C, Brenchley
Publikováno v:
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 26(5)
Publikováno v:
Arthritis Research & Therapy
The efficiency of activating latent transforming growth factor (TGF)-beta1 in systemic lupus erythematosus (SLE) may control the balance between inflammation and fibrosis, modulating the disease phenotype. To test this hypothesis we studied the abili
Autor:
Angela M. Summers, Beatrice M. Coupes, Mary Frances Brennan, Shirley A. Ralph, Colin D. Short, Paul E. C. Brenchley
Publikováno v:
Nephrology Dialysis Transplantation; Nov2005, Vol. 20 Issue 11, p2427-2432, 6p
Autor:
I. B. Houston, Robert J. Postlethwaite, T. J. Beattie, John Feehally, B. M. Coupes, Mallick Np, Paul E. C. Brenchley
Publikováno v:
New England Journal of Medicine. 310:415-420
Cyclophosphamide is widely used to induce a remission of minimal-change nephropathy, but concerns have been raised about whether its effects on cellular immunity persist after treatment is discontinued. We studied functional and numerical measures of
Publikováno v:
Nephrology Dialysis Transplantation; Oct2006, Vol. 21 Issue 10, p2681-2683, 3p