Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Paul E. Aldrich"'
Autor:
George V. De Lucca, Wayne F. Daneker, Paul E. Aldrich, Y. Ru, C.-H. Chang, Charles J. Eyermann, C.Nicholas Hodge, Edward R. Holler, Francis J. Woerner, and Joseph C. Calabrese, Robert F. Kaltenbach, Fernandez Ch, Prabhakar K. Jadhav, Patrick Y.S. Lam, George Emmett
Publikováno v:
Journal of the American Chemical Society. 120:4570-4581
One important factor influencing the affinity of a flexible ligand for a receptor is the internal strain energy required to attain the bound conformation. Calculation of fully equilibrated ensembles of bound and free ligand and receptor conformations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f445c4e3755bdb4b9da6a68a7cfc8435
https://doi.org/10.1021/ja972357h
https://doi.org/10.1021/ja972357h
Autor:
David J. Carini, Ruth R. Wexler, P. C. Wong, William A. Price, Andrew T. Chiu, S. E. Yoo, J. B. Iii Santella, Michael E. Pierce, J. V. Duncia, Alexander L. Johnson, P. B. M. W. M. Timmermans, Paul E. Aldrich, Gregory James Wells
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::133a763dc712ea46bd627111c22f8a14
https://doi.org/10.1002/chin.199152187
https://doi.org/10.1002/chin.199152187
Autor:
Paul E. Aldrich, William A. Price, J V Duncia, J B Santella rd, Ruth R. Wexler, Michael E. Pierce, Gregory J. Wells, Andrew T. Chiu, David J. Carini, Alexander L. Johnson
Publikováno v:
Journal of Medicinal Chemistry. 34:2525-2547
A new series of nonpeptide angiotensin II (AII) receptor antagonists has been prepared. These N-(biphenylyl-methyl)imidazoles, e.g. 2-butyl-1-[(2'-carboxybiphenyl-4-yl)methyl]-4-chloro-5- (hydroxymethyl)imidazole, differ from the previously reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4311658e4883941f1a0ae7028699d88
https://doi.org/10.1021/jm00112a031
https://doi.org/10.1021/jm00112a031
Publikováno v:
Biochemical and Biophysical Research Communications. 172:1195-1202
[3H]DuP 753, a nonpeptide angiotensin II (AII) receptor antagonist radioligand, was used to characterize a subtype of AII receptors in rat adrenal cortical microsomes. By Scatchard analysis, a single class of DuP 753 binding sites was found with an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae49229d07b944284b74f57047aac6f
https://doi.org/10.1016/0006-291x(90)91575-d
https://doi.org/10.1016/0006-291x(90)91575-d
Autor:
Rudolph Tamm, Albert W. Burgstahler, E. E. Van Tamelen, Maurice Shamma, Paul E. Aldrich, Joseph Wolinsky
Publikováno v:
Journal of the American Chemical Society. 91:7315-7333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327cd6ea9569cdbc36b83ef70b573819
https://doi.org/10.1021/ja01054a021
https://doi.org/10.1021/ja01054a021
Publikováno v:
Journal of the American Chemical Society. 81:6214-6221
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7f44cd388c6b590c82b7a939148255d
https://doi.org/10.1021/ja01532a027
https://doi.org/10.1021/ja01532a027
Publikováno v:
Journal of the American Chemical Society. 79:6426-6430
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ddcfbc9cf5abd29bf56fd810448af93
https://doi.org/10.1021/ja01581a019
https://doi.org/10.1021/ja01581a019
Autor:
Paul E. Aldrich, Charles F. Huebner, Oskar Wintersteiner, D. F. Dickel, M. E. Kuehne, Patrick A. Diassi, Liang H. Liu, E. Schlittler, Frank L. Weisenborn, Ernest Wenkert, Paul D. Hance, Ernest W. Robb, B. Korzun, H. B. MacPhillamy, Christiane M. Dylion, A. F. St. André, Dilip K. Roychaudhuri, Eugene E. Van Tamelen
Publikováno v:
Journal of the American Chemical Society. 81:2481-2494
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b5cc584d5e736e450c2473d9d0b42e5
https://doi.org/10.1021/ja01519a050
https://doi.org/10.1021/ja01519a050
Publikováno v:
Journal of the American Chemical Society. 78:4628-4632
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::146a7b2407ae51e363b654d3be10b8a9
https://doi.org/10.1021/ja01599a028
https://doi.org/10.1021/ja01599a028
Publikováno v:
Journal of the American Chemical Society. 81:1666-1678
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d623e47dde3aa5c5bb82c275cc4f21d8
https://doi.org/10.1021/ja01516a038
https://doi.org/10.1021/ja01516a038