Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Paul E Turner"'
Autor:
Paula F Zamora, Thomas G Reidy, Catherine R Armbruster, Ming Sun, Daria Van Tyne, Paul E Turner, Jonathan L Koff, Jennifer M Bomberger
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002566 (2024)
Phage therapy is a therapeutic approach to treat multidrug-resistant (MDR) infections that employs lytic bacteriophages (phages) to eliminate bacteria. Despite the abundant evidence for its success as an antimicrobial in Eastern Europe, there is scar
Externí odkaz:
https://doaj.org/article/6a64dc52ab974e2cb54129ada93e708c
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0263887 (2022)
Antibiotic resistant bacterial pathogens are increasingly prevalent, driving the need for alternative approaches to chemical antibiotics when treating infections. One such approach is bacteriophage therapy: the use of bacteria-specific viruses that l
Externí odkaz:
https://doaj.org/article/2823a6c8d66b4651816d0988ac6a1b0d
Autor:
Elizabeth S.C.P. Williams, Nadya M. Morales, Brian R. Wasik, Vesna eBrusic, Sean P.J. Whelan, Paul E Turner
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
Parasites and hosts can experience oscillatory cycles, where the densities of these interacting species dynamically fluctuate through time. Viruses with different replication strategies can also interact to produce cyclical dynamics. Frequent cellula
Externí odkaz:
https://doaj.org/article/829762334748491d84b59bc4f8a25ed1
Autor:
Kendra ePesko, Emily eVoigt, Adam eSwick, Valerie Joy Morley, Collin eTimm, John eYin, Paul E Turner
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
Gene order is often highly conserved within taxonomic groups, such that organisms with rearranged genomes tend to be less fit than wildtype gene orders, and suggesting natural selection favors genome architectures that maximize fitness. But it is unc
Externí odkaz:
https://doaj.org/article/8acec08916bc4c8fbcf76e812cfb2914
Autor:
Mark Sistrom, Derek Park, Heath E O'Brien, Zheng Wang, David S Guttman, Jeffrey P Townsend, Paul E Turner
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144514 (2015)
Pseudomonas syringae pv. phaseolicola (Pph) is a significant bacterial pathogen of agricultural crops, and phage Φ6 and other members of the dsRNA virus family Cystoviridae undergo lytic (virulent) infection of Pph, using the type IV pilus as the in
Externí odkaz:
https://doaj.org/article/5d06bfc7a4d44e6daa6eac9e7d474977
Publikováno v:
Frontiers in Microbiology, Vol 5 (2014)
Microbes can respond quickly to environmental disturbances through adaptation. However, processes determining the constraints on this adaptation are not well understood. One process that could affect the rate of adaptation to environmental perturbati
Externí odkaz:
https://doaj.org/article/d340ca03f5f04994ac0b31e87018e191
Publikováno v:
PLoS Genetics, Vol 8, Iss 11, p e1003102 (2012)
The modulation of fitness by single mutational substitutions during environmental change is the most fundamental consequence of natural selection. The antagonistic tradeoffs of pleiotropic mutations that can be selected under changing environments th
Externí odkaz:
https://doaj.org/article/4b1c455667904d808dc6c476c34ccb6f
Publikováno v:
PLoS Biology, Vol 3, Iss 11, p e381 (2005)
Mutational (genetic) robustness is phenotypic constancy in the face of mutational changes to the genome. Robustness is critical to the understanding of evolution because phenotypically expressed genetic variation is the fuel of natural selection. Non
Externí odkaz:
https://doaj.org/article/0cb65786ea014f2fb2e40536c44a6141
Publikováno v:
Journal of Evolutionary Biology. 35:1475-1487
Experimental evolution studies have examined coevolutionary dynamics between bacteria and lytic phages, where two models for antagonistic coevolution dominate: arms-race dynamics (ARD) and fluctuating-selection dynamics (FSD). Here, we tested the abi
Autor:
Alita R. Burmeister, Eddy Tzintzun-Tapia, Carli Roush, Ivan Mangal, Roxanna Barahman, Robert D. Bjornson, Paul E. Turner
Publikováno v:
Applied and Environmental Microbiology.
Antibiotic resistance is a persistent problem in health care and a factor that may help maintain bacterial diversity in natural environments. Bacteriophages (“phages”) are viruses that specifically infect bacteria.