Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Paul E M Phillips"'
Autor:
Jeremy J Clark, Nicholas A Nasrallah, Andrew S Hart, Anne L Collins, Ilene L Bernstein, Paul E M Phillips
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37357 (2012)
Alcohol use during adolescence has profound and enduring consequences on decision-making under risk. However, the fundamental psychological processes underlying these changes are unknown. Here, we show that alcohol use produces over-fast learning for
Externí odkaz:
https://doaj.org/article/522fe3d62a10402ab2347cd9a8bda53b
Autor:
Kenneth T Kishida, Stefan G Sandberg, Terry Lohrenz, Youssef G Comair, Ignacio Sáez, Paul E M Phillips, P Read Montague
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23291 (2011)
Fast-scan cyclic voltammetry at carbon fiber microelectrodes allows rapid (sub-second) measurements of dopamine release in behaving animals. Herein, we report the modification of existing technology and demonstrate the feasibility of making sub-secon
Externí odkaz:
https://doaj.org/article/2c869627162b4458932bf2d27fd2e8ca
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6507 (2009)
The importance of dopamine (DA) for prefrontal cortical (PFC) cognitive functions is widely recognized, but its mechanisms of action remain controversial. DA is thought to increase signal gain in active networks according to an inverted U dose-respon
Externí odkaz:
https://doaj.org/article/7be97d3a624e4ed992359c3bc2f49f06
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
Alcohol use remains a major public health concern and is especially prevalent during adolescence. Adolescent alcohol use has been linked to several behavioral abnormalities in later life, including increased risk taking and impulsivity. Accordingly,
Externí odkaz:
https://doaj.org/article/b3c7d6617de44465829862641ec9e5b4
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2022)
The actions of corticotropin-releasing factor (CRF) in the core of the nucleus accumbens including increasing dopamine release and inducing conditioned place preference in stress-naïve animals. However, following two-day, repeated forced swim stress
Externí odkaz:
https://doaj.org/article/90f1794fe903429887bfce2f1a462aea
Autor:
Britahny Baskin, Suhjung Janet Lee, Emma Skillen, Katrina Wong, Holly Rau, Rebecca C. Hendrickson, Kathleen Pagulayan, Murray A. Raskind, Elaine R. Peskind, Paul E. M. Phillips, David G. Cook, Abigail G. Schindler
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Blast exposure (via detonation of high explosives) represents a major potential trauma source for Servicemembers and Veterans, often resulting in mild traumatic brain injury (mTBI). Executive dysfunction (e.g., alterations in memory, deficits in ment
Externí odkaz:
https://doaj.org/article/35d906ebecf3496eadbd9aa558ede290
Autor:
Selena S. Schattauer, Benjamin B. Land, Kathryn L. Reichard, Antony D. Abraham, Lauren M. Burgeno, Jamie R. Kuhar, Paul E. M. Phillips, Shao En Ong, Charles Chavkin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Opioid receptors are important modulators of nociceptive pain. Here the authors show that opioid receptor activation recruits peroxiredoxin 6 (PRDX6) to the receptor-Gαi complex by c-Jun N-terminal kinase, resulting in Gαi depalmitoylation and enha
Externí odkaz:
https://doaj.org/article/663c11deb7974a19a4ce19a91ea13d73
Autor:
Lauren M. Burgeno, Ryan D. Farero, Nicole L. Murray, Marios C. Panayi, Jennifer S. Steger, Marta E. Soden, Scott B. Evans, Stefan G. Sandberg, Ingo Willuhn, Larry S. Zweifel, Paul E. M. Phillips
In some individuals, drug-associated cues subsume potent control of behavior, such as the elicitation of drug craving1–3and automatized drug use4. The intensity of this cue reactivity is highly predictive of relapse and other clinical outcomes in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9883809c42e15b5bd45f359e254d0f8c
https://doi.org/10.1101/2023.04.09.536189
https://doi.org/10.1101/2023.04.09.536189
Autor:
Abigail G. Schindler, Larry S. Zweifel, David G. Cook, Britahny M. Baskin, Paul E. M. Phillips, Rebecca C. Hendrickson, Kathleen F. Pagulayan, Elaine R. Peskind, Barbara Juarez, Murray A. Raskind, Suhjung Janet Lee
Publikováno v:
Alcohol Clin Exp Res
Background Mild traumatic brain injury (mTBI) is common in civilians and highly prevalent among military service members. mTBI can increase health risk behaviors (e.g., sensation seeking, impulsivity) and addiction risk (e.g., for alcohol use disorde
Catecholaminergic Innervation of the Lateral Nucleus of the Cerebellum Modulates Cognitive Behaviors
Autor:
Timothy M. Locke, Martin Darvas, Steven A. Thomas, Avery C. Hunker, Stefan G. Sandberg, Abigail G. Schindler, Larry S. Zweifel, Paul E. M. Phillips, Julianne M. Geller, Erik S. Carlson
Publikováno v:
J Neurosci
The cerebellum processes neural signals related to rewarding and aversive stimuli, suggesting that the cerebellum supports nonmotor functions in cognitive and emotional domains. Catecholamines are a class of neuromodulatory neurotransmitters well kno