Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Paul E M Phillips"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
Alcohol use remains a major public health concern and is especially prevalent during adolescence. Adolescent alcohol use has been linked to several behavioral abnormalities in later life, including increased risk taking and impulsivity. Accordingly,
Externí odkaz:
https://doaj.org/article/b3c7d6617de44465829862641ec9e5b4
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2022)
The actions of corticotropin-releasing factor (CRF) in the core of the nucleus accumbens including increasing dopamine release and inducing conditioned place preference in stress-naïve animals. However, following two-day, repeated forced swim stress
Externí odkaz:
https://doaj.org/article/90f1794fe903429887bfce2f1a462aea
Autor:
Britahny Baskin, Suhjung Janet Lee, Emma Skillen, Katrina Wong, Holly Rau, Rebecca C. Hendrickson, Kathleen Pagulayan, Murray A. Raskind, Elaine R. Peskind, Paul E. M. Phillips, David G. Cook, Abigail G. Schindler
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Blast exposure (via detonation of high explosives) represents a major potential trauma source for Servicemembers and Veterans, often resulting in mild traumatic brain injury (mTBI). Executive dysfunction (e.g., alterations in memory, deficits in ment
Externí odkaz:
https://doaj.org/article/35d906ebecf3496eadbd9aa558ede290
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Stress is highly pervasive in humans, impacting motivated behaviors with an enormous toll on life quality. Many of the effects of stress are orchestrated by neuropeptides such as corticotropin-releasing factor (CRF). It has previously been shown that
Externí odkaz:
https://doaj.org/article/87439fc26b8f43e89872c5f4d00e3224
Autor:
Selena S. Schattauer, Benjamin B. Land, Kathryn L. Reichard, Antony D. Abraham, Lauren M. Burgeno, Jamie R. Kuhar, Paul E. M. Phillips, Shao En Ong, Charles Chavkin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Opioid receptors are important modulators of nociceptive pain. Here the authors show that opioid receptor activation recruits peroxiredoxin 6 (PRDX6) to the receptor-Gαi complex by c-Jun N-terminal kinase, resulting in Gαi depalmitoylation and enha
Externí odkaz:
https://doaj.org/article/663c11deb7974a19a4ce19a91ea13d73
Autor:
Lauren M. Burgeno, Ryan D. Farero, Nicole L. Murray, Marios C. Panayi, Jennifer S. Steger, Marta E. Soden, Scott B. Evans, Stefan G. Sandberg, Ingo Willuhn, Larry S. Zweifel, Paul E. M. Phillips
In some individuals, drug-associated cues subsume potent control of behavior, such as the elicitation of drug craving1–3and automatized drug use4. The intensity of this cue reactivity is highly predictive of relapse and other clinical outcomes in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9883809c42e15b5bd45f359e254d0f8c
https://doi.org/10.1101/2023.04.09.536189
https://doi.org/10.1101/2023.04.09.536189
Autor:
Abigail G. Schindler, Larry S. Zweifel, David G. Cook, Britahny M. Baskin, Paul E. M. Phillips, Rebecca C. Hendrickson, Kathleen F. Pagulayan, Elaine R. Peskind, Barbara Juarez, Murray A. Raskind, Suhjung Janet Lee
Publikováno v:
Alcohol Clin Exp Res
Background Mild traumatic brain injury (mTBI) is common in civilians and highly prevalent among military service members. mTBI can increase health risk behaviors (e.g., sensation seeking, impulsivity) and addiction risk (e.g., for alcohol use disorde
Catecholaminergic Innervation of the Lateral Nucleus of the Cerebellum Modulates Cognitive Behaviors
Autor:
Timothy M. Locke, Martin Darvas, Steven A. Thomas, Avery C. Hunker, Stefan G. Sandberg, Abigail G. Schindler, Larry S. Zweifel, Paul E. M. Phillips, Julianne M. Geller, Erik S. Carlson
Publikováno v:
J Neurosci
The cerebellum processes neural signals related to rewarding and aversive stimuli, suggesting that the cerebellum supports nonmotor functions in cognitive and emotional domains. Catecholamines are a class of neuromodulatory neurotransmitters well kno
Autor:
Guangfu Wu, Nannan Zhang, Avi Matarasso, Ian Heck, Huijie Li, Wei Lu, J. Glenn Phaup, Michael J. Schneider, Yixin Wu, Zhengyan Weng, He Sun, Zan Gao, Xincheng Zhang, Stefan G. Sandberg, Dilruba Parvin, Elena Seaholm, Syed Kamrul Islam, Xueju Wang, Paul E. M. Phillips, Daniel C. Castro, Shinghua Ding, De-Pei Li, Michael R. Bruchas, Yi Zhang
Publikováno v:
Nano Lett
The real-time monitoring of neurochemical release in vivo plays a critical role in understanding the biochemical process of the complex nervous system. Current technologies for such applications, including microdialysis and fast-scan cyclic voltammet
Autor:
Eva Vigato, Nilesh W. Gaikwad, Ryan D. Farero, Kristen A. Keefe, Randall T. Peterson, Roberto Cadeddu, Gabriele Floris, Tejia Zhang, Gabriel D. Bossé, Suhjung J. Lee, Marco Bortolato, Paul E. M. Phillips
Publikováno v:
J Clin Invest
Opioid use disorder (OUD) has become a leading cause of death in the United States, yet current therapeutic strategies remain highly inadequate. To identify potential treatments for OUD, we screened a targeted selection of over 100 drugs using a rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f3c070ce8a5221dbc5b2042259a29a
https://europepmc.org/articles/PMC8121512/
https://europepmc.org/articles/PMC8121512/