Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Paul E, Neiman"'
Publikováno v:
PLoS Genetics, Vol 4, Iss 7, p e1000132 (2008)
Genetic instability plays a key role in the formation of naturally occurring cancer. The formation of long DNA palindromes is a rate-limiting step in gene amplification, a common form of tumor-associated genetic instability. Genome-wide analysis of p
Externí odkaz:
https://doaj.org/article/8cfa54f3ec194f34a9223aab1243f3d7
Autor:
William A. Weiss, Christopher S. Hackett, Ashlee E. Tyler, Katrina Elsaesser, Zizhen Yao, James M. Olson, Christopher J. Kemp, Paul E. Neiman, Stephen J. Tapscott, Joyoti Dey, Scott J. Diede, Christopher C. Keyes
Publikováno v:
Epigenetics, vol 8, iss 12
Genetic and epigenetic alterations are essential for the initiation and progression of human cancer. We previously reported that primary human medulloblastomas showed extensive cancer-specific CpG island DNA hypermethylation in critical developmental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e5c5d1ce2e83a9c6b6a04896ac23d9
https://doi.org/10.4161/epi.26486
https://doi.org/10.4161/epi.26486
Autor:
Robert Kimmel, Paul E. Neiman, Joan Burnside, Sandra J Bowers, Jeffrey J. Delrow, Katrina Elsaesser, Amalia Icreverzi
Publikováno v:
Oncogene. 25:6325-6335
Retroviral vector-mediated overexpression of c-myc in embryonic bursal precursors induces multi-staged tumorigenesis beginning with preneoplastic-transformed follicles (TF) and progressing to clonal metastatic B-cell lymphomas. Using a 13K chicken cD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13bd6fb4ed3ec3940d78c9a136b27b08
https://doi.org/10.1038/sj.onc.1209646
https://doi.org/10.1038/sj.onc.1209646
Publikováno v:
Oncogene. 23:4413-4421
Avian leukosis virus (ALV) induces bursal lymphoma in tumor-susceptible chicken strains after proviral integration within the c-myc gene, and subsequent expansion of Myc-overexpressing lymphocytes within transformed follicles. Line 6(3) strain chicke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ba225bdcdec27d6dd83c41f2741800
https://doi.org/10.1038/sj.onc.1207577
https://doi.org/10.1038/sj.onc.1207577
Publikováno v:
Oncogene. 23:2357-2366
We have used chicken cDNA microarrays to investigate gene-expression changes induced during transformation of chick embryo fibroblasts (CEF) by the viral Jun oncoprotein encoded by ASV17. This analysis reveals that v-Jun induces increases and decreas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cc684e79d31d6164731eee3b0eaa33
https://doi.org/10.1038/sj.onc.1207377
https://doi.org/10.1038/sj.onc.1207377
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1520:187-194
Mouse Boo/Diva is an ovary-specific member of the Bcl-2 family identified through homology with the avian cell death antagonist NR13. We identified a human orthologue of Boo/Diva, which is highly conserved between mouse and human and related to avian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add43828ac50b6fa69b2856f67f68c92
https://doi.org/10.1016/s0167-4781(01)00268-8
https://doi.org/10.1016/s0167-4781(01)00268-8
Publikováno v:
Oncogene. 20:3226-3234
Avian leukosis virus induces lymphoma in chickens after proviral integration within the c-Myc gene, and subsequent expansion of Myc-overexpressing lymphocytes within transformed bursal follicles. The clonal expansion of these follicles allowed us to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a148b86a8007c1af1653840ce2cdcd
https://doi.org/10.1038/sj.onc.1204431
https://doi.org/10.1038/sj.onc.1204431
Publikováno v:
Oncogene. 19:2780-2785
Angiogenesis was identified as an early consequence of myc gene overexpression in two models of retroviral lymphomagenesis. Avian leukosis virus (ALV) induces bursal lymphoma in chickens after proviral c-myc gene integration, while the HB-1 retroviru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186649efc9f7887e95950b3683c65321
https://doi.org/10.1038/sj.onc.1203589
https://doi.org/10.1038/sj.onc.1203589
Autor:
Paul E. Neiman
Publikováno v:
Journal of Cellular Physiology. 177:518-524
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::252dacc188f714d5d662e84f32e2f4a9
https://doi.org/10.1002/(sici)1097-4652(199812)177:4<518::aid-jcp3>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199812)177:4<518::aid-jcp3>3.0.co