Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Paul Dietl"'
Autor:
Paul Dietl, Manfred Frick
Publikováno v:
Cells, Vol 11, Iss 1, p 45 (2021)
The lamellar body (LB) of the alveolar type II (ATII) cell is a lysosome-related organelle (LRO) that contains surfactant, a complex mix of mainly lipids and specific surfactant proteins. The major function of surfactant in the lung is the reduction
Externí odkaz:
https://doaj.org/article/80b8668a7f7343d1b0c02e0b17d291bd
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10982 (2010)
Ca(2+) is essential for vesicle fusion with the plasma membrane in virtually all types of regulated exocytoses. However, in contrast to the well-known effects of a high cytoplasmic Ca(2+) concentration ([Ca(2+)](c)) in the prefusion phase, the occurr
Externí odkaz:
https://doaj.org/article/38f44303e5ac4c7093b1239540ee7f18
Autor:
Paul Dietl, Manfred Frick
Publikováno v:
Cells, Vol 11, Iss 45, p 45 (2022)
Cells
Cells
The lamellar body (LB) of the alveolar type II (ATII) cell is a lysosome-related organelle (LRO) that contains surfactant, a complex mix of mainly lipids and specific surfactant proteins. The major function of surfactant in the lung is the reduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2641199b6f20b08e0401beac122b413
https://www.mdpi.com/2073-4409/11/1/45
https://www.mdpi.com/2073-4409/11/1/45
Autor:
Hanna Schmidt, Lara Guthjahr, Alexander Sauter, Fabian Zech, Rayhane Nchioua, Steffen Stenger, Manfred Frick, Frank Kirchhoff, Paul Dietl, Oliver H. Wittekindt
Publikováno v:
American journal of physiology. Cell physiology. 322(4)
Primary airway epithelial cells (pAECs) cultivated at air-liquid interface (ALI) conditions are widely used as surrogates for human in vivo epithelia. To extend the proliferative capacity and to enable serially passaging of pAECs, conditional reprogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54122c11e5a3480a101a5ea1aee5cd17
https://pubmed.ncbi.nlm.nih.gov/35196166
https://pubmed.ncbi.nlm.nih.gov/35196166
Autor:
Ana M. Jaramillo, Manfred Frick, Veronika Eva Winkelmann, Oliver H. Wittekindt, Michael J. Tuvim, Paul Dietl, Kristin E. Thompson, Wei Han, Hanna Schmidt, Kathrin Neuland, Burton F. Dickey, Giorgio Fois
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 316:L58-L70
Mucus clearance provides an essential innate defense mechanism to keep the airways and lungs free of particles and pathogens. Baseline and stimulated mucin secretion from secretory airway epithelial cells need to be tightly regulated to prevent mucus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8969a8b581e6d3ec7885ad707ea598c
https://doi.org/10.1152/ajplung.00157.2018
https://doi.org/10.1152/ajplung.00157.2018
Publikováno v:
Sustainable Production, Life Cycle Engineering and Management ISBN: 9789811567780
The potential of digital technologies is widely discussed and recognized, mainly focusing on process automation, efficiency improvements and quality control. The implications on environmental sustainability is mostly considered from a theoretical per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb266197e7090b1b6687145ea593eef3
https://doi.org/10.1007/978-981-15-6779-7_18
https://doi.org/10.1007/978-981-15-6779-7_18
Autor:
Giorgio Fois, Oliver H. Wittekindt, Michael Fauler, Carolin Kling, Karl J. Föhr, Manfred Frick, Paul Dietl
Publikováno v:
The Journal of Physiology. 596:4893-4907
KEY POINTS Re-sensitization of P2X4 receptors depends on a protonation/de-protonation cycle Protonation and de-protonation of the receptors is achieved by internalization and recycling of P2X4 receptors via acidic compartments Protonation and de-prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b418e3510d6bf5b8d33ac8c60467840
https://doi.org/10.1113/jp275448
https://doi.org/10.1113/jp275448
Autor:
Jean-Michel Sallenave, Paul Dietl, Brigitte Solhonne, Ignacio Garcia-Verdugo, Bérengère Villeret, Alexandra Dieu, Rémi Le Borgne, Marjolène Straube, Xavier Norel, François Rouzet, Pika Miklavc, Joel Aerts, Sena Hamadi, Arnaud Mailleux, Devy Diallo
Publikováno v:
ACS Nano. 12:1188-1202
Silver nanoparticles (AgNPs) are microbicidal agents which could be potentially used as an alternative to antivirals to treat human infectious diseases, especially influenza virus infections where antivirals have generally proven unsuccessful. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de41af18d2f872aa88eb3bee3ee2110c
https://doi.org/10.1021/acsnano.7b06934
https://doi.org/10.1021/acsnano.7b06934
Autor:
Manfred Frick, Boris Mizaikoff, Paul Dietl, Kristin E. Thompson, Christiane Michel, Peter Braubach, Hanna Schmidt, Michael Fauler, Oliver H. Wittekindt, Daniel Neubauer
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 56:372-382
The apical surface liquid (ASL) layer covers the airways and forms a first line of defense against pathogens. Maintenance of ASL volume by airway epithelia is essential for maintaining lung function. The proteolytic activation of epithelial Na+ chann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4e98685f8c01f121be7e15480ecdef
https://doi.org/10.1165/rcmb.2016-0161oc
https://doi.org/10.1165/rcmb.2016-0161oc
Autor:
Robin Lochbaum, Oliver H. Wittekindt, Manfred Frick, Paul Dietl, Danny Jonigk, Peter Braubach, Hanna Schmidt, Kathrin Neuland, Carolin Schilpp, Kristin Thompson
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 13
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3222 (2019)
Volume 20
Issue 13
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3222 (2019)
Interleukin-13 (IL-13) drives symptoms in asthma with high levels of T-helper type 2 cells (Th2-cells). Since tight junctions (TJ) constitute the epithelial diffusion barrier, we investigated the effect of IL-13 on TJ in human tracheal epithelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d46c6d078a347dc85cc50945b274bf6