Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Paul Dieter Niedmann"'
Autor:
Stefan Bleich, C. Berger, Paul Dieter Niedmann, Johannes Kornhuber, Geert Mayer, Wolfgang Jordan, E. Rüther, N. von Ahsen, Stefan Cohrs, Andrea Rodenbeck
Publikováno v:
Journal of Neural Transmission. 111:683-689
Assessment of serum total homocysteine (tHcy) in patients with obstructive sleep apnea (OSA) syndrome is highly relevant since both are strongly associated with stroke and cognitive dysfunction. Seven of 16 untreated OSA patients showed tHcy levels e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffe118db7c4bcb87b4fb60ef4755924
https://doi.org/10.1007/s00702-004-0130-2
https://doi.org/10.1007/s00702-004-0130-2
Autor:
Victor W. Armstrong, Eberhard Wieland, Paul Dieter Niedmann, Maria Shipkova, Michael Oellerich
Publikováno v:
Clinical Chemistry. 50:438-441
Determination of thiopurine S -methyltransferase (TPMT; EC 2.1.1.67) activity is intended to screen patients before therapy with thiopurine drugs (6-mercaptopurine, 6-thioguanine, and azathioprine) to rule out a deficiency in this enzyme. The enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d95dd646b9df36f4e9e150c44428c59
https://doi.org/10.1373/clinchem.2003.026096
https://doi.org/10.1373/clinchem.2003.026096
Autor:
Eberhard Wieland, Michael Oellerich, Ulrike Schellhaas, Paul Dieter Niedmann, Ekkehard Schütz, Victor W. Armstrong, Maria Shipkova
Publikováno v:
Clinical Biochemistry. 33:107-113
Objectives: We have identified an acyl glucuronide (M-2) of the immunosuppressant mycophenolic acid (MPA). Acyl glucuronides have toxic potential and may contribute to drug toxicity. Whether acyl glucuronides are able to induce release of proinflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e93e74efe12dcd7f26045bec02b45f9
https://doi.org/10.1016/s0009-9120(99)00101-0
https://doi.org/10.1016/s0009-9120(99)00101-0
Autor:
Maria Shipkova, Gerald Brenner-Weiß, Michael Oellerich, Martin Voihsel, Victor W. Armstrong, Ekkehard Schütz, Paul Dieter Niedmann, Eberhard Wieland, Felix Braun
Publikováno v:
British Journal of Pharmacology. 126:1075-1082
1. Mycophenolic acid (MPA), is primarily metabolized in the liver to 7-O-MPA-beta-glucuronide (MPAG). Using RP-h.p.l.c. we observed three further MPA metabolites, M-1, M-2, M-3, in plasma of transplant recipients on MMF therapy. To obtain information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53c55dd4d1afe1498cc8b03c108bc3fb
https://doi.org/10.1038/sj.bjp.0702399
https://doi.org/10.1038/sj.bjp.0702399
Autor:
Maria Shipkova, Leslie M. Shaw, Eberhard Wieland, Paul Dieter Niedmann, Ekkehard Schütz, Victor W. Armstrong, Michael Oellerich
Publikováno v:
Clinical Chemistry. 44:1481-1488
We describe a reversed-phase HPLC method for determination of total mycophenolic acid (MPA), its free concentration (MPAf), and the glucuronide metabolite (MPAG), based on simple sample preparation and gradient elution chromatography. The compounds w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0ab117e1ddac9bb267e8eb4290fdc68
https://doi.org/10.1093/clinchem/44.7.1481
https://doi.org/10.1093/clinchem/44.7.1481
Autor:
Victor W. Armstrong, Eberhard Wieland, Maria Shipkova, Ekkehard Schütz, Paul Dieter Niedmann, Michael Oellerich
Publikováno v:
Clinical Chemistry. 44:1269-1274
Hyperbilirubinemia, which frequently occurs in severe liver disease, interferes with the fluorescence polarization immunoassay (FPIA) monoethylglycinexylidide (MEGX) assay manufactured by Abbott Diagnostics. Because the MEGX test is particularly help
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa5356717b080738e4386c5b3ac0873
https://doi.org/10.1093/clinchem/44.6.1269
https://doi.org/10.1093/clinchem/44.6.1269
Autor:
Hermann H. Klein, Klaus Nebendahl, Stefanie Lindert-Heimberg, Sibylle Pich, Paul Dieter Niedmann
Publikováno v:
Journal of Molecular and Cellular Cardiology. 25:103-112
Lipid peroxidation, presumably the result of free radical-mediated injury, has been shown to occur during myocardial ischemia and reperfusion. Since vitamin E is a very effective, naturally occurring, chain-breaking antioxidant, it was investigated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9223c3472548169d82e2022a3251ae7
https://doi.org/10.1006/jmcc.1993.1011
https://doi.org/10.1006/jmcc.1993.1011
Autor:
Victor W. Armstrong, Borwin Bandelow, Jens Wiltfang, Stefan Bleich, Peter Müller, Bettina Schenk-Daprá, Gerthild Stiens, Eckart Rüther, Paul Dieter Niedmann
Publikováno v:
Scopus-Elsevier
CIÊNCIAVITAE
CIÊNCIAVITAE
Objective The goal of this study was to identify adverse effects of the atypical neuroleptic clozapine on liver function and lipid metabolism. Methods Data which included serum levels of clozapine and its hepatic metabolite N-desmethyl clozapine were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb5dfd5877e0442b772c9bc471cbe61
https://doi.org/10.1007/pl00007544
https://doi.org/10.1007/pl00007544
Autor:
Helga Rehder, Barbara Zoll, Jürgen Bernert, Ingo Hansmann, Gudrun Gatz, Paul Dieter Niedmann, Martina Heyat, Iris Bartels, Claus Waldenmaier
Publikováno v:
American Journal of Medical Genetics. 42:747-750
Prenatal cytogenetic analysis at 11 weeks of gestation revealed an abnormal karyotype 47,XX,+mar in all metaphases obtained from a chorionic villi sample after 24 h culture. Karyotyping of amniotic fluid cells in the second trimester showed mosaicism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2836dcd14940a557f990ff061a0531d0
https://doi.org/10.1002/ajmg.1320420525
https://doi.org/10.1002/ajmg.1320420525
Publikováno v:
Basic Research in Cardiology. 86:32-39
Thirty pigs were randomly assigned to a blind treatment with vitamin E or placebo. Ten animals each received 0.5 g d-alpha tocopherol intravenously before ischemia (group 1) or before reperfusion (group 2). Ten control pigs were treated with a lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219e38f447ea2f0d1b5f518ce2a8617d
https://doi.org/10.1007/bf02193869
https://doi.org/10.1007/bf02193869