Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paul Denver"'
Autor:
Qiu-Lan Ma, Cansheng Zhu, Marco Morselli, Trent Su, Matteo Pelligrini, Zhengqi Lu, Mychica Jones, Paul Denver, Daniel Castro, Xuelin Gu, Frances Relampagos, Kaitlin Caoili, Bruce Teter, Sally A. Frautschy, Gregory M. Cole
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neuroinflammation plays a crucial role in the development and progression of Alzheimer's disease (AD), in which activated microglia are found to be associated with neurodegeneration. However, there is limited evidence showing how neuroinflammation an
Externí odkaz:
https://doaj.org/article/bdb572081193451080868c064d87e8c1
Autor:
Paul Denver, Paula L McClean
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 10, Pp 1719-1730 (2018)
As populations age, prevalence of Alzheimer's disease (AD) is rising. Over 100 years of research has provided valuable insights into the pathophysiology of the disease, for which age is the principal risk factor. However, in recent years, a multitude
Externí odkaz:
https://doaj.org/article/62b882641e5f41d5b3fdda52f4f58fce
Autor:
Paul Denver, Heather D’Adamo, Shuxin Hu, Xiaohong Zuo, Cansheng Zhu, Chihiro Okuma, Peter Kim, Daniel Castro, Mychica R. Jones, Carmen Leal, Marisa Mekkittikul, Elham Ghadishah, Bruce Teter, Harry V. Vinters, Gregory Michael Cole, Sally A. Frautschy
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Alzheimer’s disease (AD) and mixed dementia (MxD) comprise the majority of dementia cases in the growing global aging population. MxD describes the coexistence of AD pathology with vascular pathology, including cerebral small vessel disease (SVD).
Externí odkaz:
https://doaj.org/article/d8dfc5a5a3ef4ae4be442906e4dd5013
Autor:
Maximilian Ackermann, Simon C. Satchell, Christopher A. Mitchell, Patricia Kelly, Moritz A. Konerding, Paul Denver
Publikováno v:
Angiogenesis
Kelly, P, Denver, P, Satchell, S C, Ackermann, M, Konerding, M A & Mitchell, C A 2017, ' Microvascular ultrastructural changes precede cognitive impairment in the murine APPswe/PS1dE9 model of Alzheimer's disease ', Angiogenesis, vol. 20, no. 4, pp. 567-580 . https://doi.org/10.1007/s10456-017-9568-3
Kelly, P, Denver, P, Satchell, S C, Ackermann, M, Konerding, M A & Mitchell, C A 2017, ' Microvascular ultrastructural changes precede cognitive impairment in the murine APPswe/PS1dE9 model of Alzheimer's disease ', Angiogenesis, vol. 20, no. 4, pp. 567-580 . https://doi.org/10.1007/s10456-017-9568-3
Cerebral and systemic organ microvascular pathologies coexist with human Alzheimer's disease (AD) neuropathology. In this study, we hypothesised that both cerebral and systemic microvascular pathologies exist in 4- to 5-month-old male APPswe/PS1dE9 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fa63848ff89050eb214bc167e6d76a
https://doi.org/10.1007/s10456-017-9568-3
https://doi.org/10.1007/s10456-017-9568-3
Autor:
Chansheng Zhu, Gregory M. Cole, Paul Denver, Sally A. Frautschy, Mychica Jones, Bruce Teter, Qiulan-Ma Ma
Publikováno v:
Alzheimer's & Dementia. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51fe3d1c3f7e58decb6eee2b9a6c12dd
https://doi.org/10.1016/j.jalz.2019.09.048
https://doi.org/10.1016/j.jalz.2019.09.048
Publikováno v:
Brain, behavior, and immunity. 70
Cognitive dysfunction and neuroinflammation are typical in Alzheimer’s disease (AD), but are also associated with normal aging, albeit less severely. Insulin resistance in the brain has been demonstrated in AD patients and is thought to be involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797ad3a557021c809212484de6d4c59e
https://pubmed.ncbi.nlm.nih.gov/29604345
https://pubmed.ncbi.nlm.nih.gov/29604345
Publikováno v:
Alzheimer's & Dementia. 15:P544-P544
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c3d1497601e274a9f5badf2aea1b313
https://doi.org/10.1016/j.jalz.2019.06.4472
https://doi.org/10.1016/j.jalz.2019.06.4472
Autor:
Paula McClean, Paul Denver
Publikováno v:
Neural Regeneration Research
Neural Regeneration Research, Vol 13, Iss 10, Pp 1719-1730 (2018)
Neural Regeneration Research, Vol 13, Iss 10, Pp 1719-1730 (2018)
As populations age, prevalence of Alzheimer's disease (AD) is rising. Over 100 years of research has provided valuable insights into the pathophysiology of the disease, for which age is the principal risk factor. However, in recent years, a multitude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5094d3cc454859c22332fc0b07131a3d
https://doi.org/10.4103/1673-5374.238608
https://doi.org/10.4103/1673-5374.238608
Publikováno v:
World Journal of Gastroenterology. 19:1770
To investigate the role of psychological characteristics as risk factors for oesophageal adenocarcinoma (OAC), as well as the reflux-mediated precursor pathway.An all-Ireland population-based case-control study recruited 230 reflux oesophagitis (RO),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a7dfee2183c2d2dc7b033e4c330436
https://doi.org/10.3748/wjg.v19.i11.1770
https://doi.org/10.3748/wjg.v19.i11.1770