Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Paul Debbage"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8932 (2021)
Nanoparticles bearing specific targeting groups can, in principle, accumulate exclusively at lesion sites bearing target molecules, and release therapeutic agents there. However, practical application of targeted nanoparticles in the living organism
Externí odkaz:
https://doaj.org/article/a18123b7e01c4e27ad95dca81264b155
Autor:
Paul Debbage, Gudrun C. Thurner
Publikováno v:
Pharmaceuticals, Vol 3, Iss 11, Pp 3371-3416 (2010)
Targeted nanoparticles have the potential to improve drug delivery efficiencies by more than two orders of magnitude, from the ~ 0.1% which is common today. Most pharmacologically agents on the market today are small drug molecules, which diffuse acr
Externí odkaz:
https://doaj.org/article/791a68190f7a4ea48bac8330f0940f19
Publikováno v:
Nanoscale Advances. 5:503-512
Simple and up-scalable synthesis method for human serum albumin nanoparticles with narrow size distribution, tunable size range, stable and reproducible.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448ea7155a64462abe351ae82c0fc3be
https://doi.org/10.1039/d2na00413e
https://doi.org/10.1039/d2na00413e
Autor:
Paul Debbage, Christian Kremser, Klaudia Mistlberger, Thomas H. Helbich, Bernhard K. Keppler, Dieter Baurecht, Kristian Pfaller, Heribert Talasz, Irena Pashkunova-Martic, Werner Jaschke, Beate Bechter-Hugl
Publikováno v:
Journal of Nanoparticle Research. 23
Molecular imaging using magnetic resonance imaging (MRI) is expected to play a crucial future role in oncological diagnosis and in monitoring of therapeutic progress. Targeted nanoparticle contrast media (CM) with high relaxivities are required in or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cf9ee10f9a721907c2159f02da2ed3b
https://doi.org/10.1007/s11051-021-05157-w
https://doi.org/10.1007/s11051-021-05157-w
Autor:
Anna Helbok, Werner Jaschke, Christian Kremser, Klammsteiner N, Paul Debbage, Maria M Stollenwerk, K Albrecht-Schgoer, E. A. Wallnöfer, Gudrun C. Thurner, Heribert Talasz, Hermann Dietrich
Publikováno v:
Histochemistry and cell biology. 155(1)
This multidisciplinary study examined the pharmacokinetics of nanoparticles based on albumin-DTPA-gadolinium chelates, testing the hypothesis that these nanoparticles create a stronger vessel signal than conventional gadolinium-based contrast agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b40337033249ff1d866468aef6c956
https://pubmed.ncbi.nlm.nih.gov/33040183
https://pubmed.ncbi.nlm.nih.gov/33040183
Autor:
Gudrun C. Thurner, Paul Debbage
Publikováno v:
Histochemistry and Cell Biology
We explore present-day trends and challenges in nanomedicine. Creativity in the laboratories continues: the published literature on novel nanoparticles is now vast. Nanoagents are discussed here which are composed entirely of strongly photoluminescen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c677a5a852aec75dac032a1602de17d2
http://europepmc.org/articles/PMC6267421
http://europepmc.org/articles/PMC6267421
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 8932, p 8932 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 8932, p 8932 (2021)
Nanoparticles bearing specific targeting groups can, in principle, accumulate exclusively at lesion sites bearing target molecules, and release therapeutic agents there. However, practical application of targeted nanoparticles in the living organism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94604ae334d42ca2aa48c8b2b48aeb29
https://doi.org/10.3390/ijms22168932
https://doi.org/10.3390/ijms22168932
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 55:679-681
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb51699448fe3cc57440a5f1cc6a131
https://doi.org/10.5414/cpxces15ea02
https://doi.org/10.5414/cpxces15ea02
Publikováno v:
Seminars in Cancer Biology. 31:36-42
DNA damaging agents (ionizing radiation and chemotherapeutics) are considered as most effective in cancer treatment. However, there is a subpopulation of carcinoma cells within the tumour demonstrating resistance to DNA damaging treatment approaches.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3431e9caa1fada36f829ce25a11eef38
https://doi.org/10.1016/j.semcancer.2014.06.002
https://doi.org/10.1016/j.semcancer.2014.06.002
Autor:
Peter Lukas, Christoph Reinhold Arnold, Paul Debbage, Gudrun C. Thurner, Sergej Skvortsov, Ira-Ida Skvortsova, Alshaimaa Abdelmoez
Publikováno v:
Oncoscience
Metastatic progression of malignant tumors resistant to conventional therapeutic approaches is an ultimate challenge in clinical oncology. Despite the efforts of basic and clinical researchers, there is still no effective treatment schedule to preven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6645ea2d6b9629ee3b27cb5f2a5d5dd4
https://doi.org/10.18632/oncoscience.74
https://doi.org/10.18632/oncoscience.74