Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Paul D. Soloway"'
Autor:
Seoyeon Lee, Abigail M. Benvie, Hui Gyu Park, Roman Spektor, Blaine Harlan, J. Thomas Brenna, Daniel C. Berry, Paul D. Soloway
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Adipocyte beiging is a thermogenic response to cold exposure and b3-adrenergic receptor agonists, which exert their effects by distinct and common molecular mechanisms that control chromatin accessibility and lipid metabolism.
Externí odkaz:
https://doaj.org/article/9ecacc2372344959befed191d75666c6
Autor:
Pei-Yin Tsai, Bo Shui, Seoyeon Lee, Yang Liu, Yue Qu, Chloe Cheng, Kaydine Edwards, Callie Wong, Ryan Meng-Killeen, Paul D. Soloway, Joeva J. Barrow
Publikováno v:
Nutrients, Vol 15, Iss 16, p 3532 (2023)
Non-shivering thermogenesis (NST) has strong potential to combat obesity; however, a safe molecular approach to activate this process has not yet been identified. The sulfur amino acid taurine has the ability to safely activate NST and confer protect
Externí odkaz:
https://doaj.org/article/2966a418b1884fd781e73098c53c105f
Autor:
Blaine Harlan, Hui Gyu Park, Roman Spektor, Bethany Cummings, J. Thomas Brenna, Paul D. Soloway
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
Obesity promotes type 2 diabetes and cardiometabolic pathologies. Vertical sleeve gastrectomy (VSG) is used to treat obesity resulting in long-term weight loss and health improvements that precede weight loss; however, the mechanisms underlying the i
Externí odkaz:
https://doaj.org/article/1b24acb0632749408fa78c5af55cd0ab
Autor:
Adam B. Francisco, Jine Li, Alaa R. Farghli, Matt Kanke, Bo Shui, Paul R. Munn, Jennifer K. Grenier, Paul D. Soloway, Zhangjie Wang, Lola M. Reid, Jian Liu, Praveen Sethupathy
Publikováno v:
Cancer Research Communications. 2:663-678
Fibrolamellar carcinoma (FLC) is an aggressive liver cancer with no effective therapeutic options. The extracellular environment of FLC tumors is poorly characterized and may contribute to cancer growth and/or metastasis. To bridge this knowledge gap
Autor:
Praveen Sethupathy, Jian Liu, Lola M. Reid, Zhangjie Wang, Paul D. Soloway, Jennifer K. Grenier, Paul R. Munn, Bo Shui, Matt Kanke, Alaa R. Farghli, Jine Li, Adam B. Francisco
All supplemental figures with legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27766146d74ed059731b27980765e8f4
https://doi.org/10.1158/2767-9764.22545009.v1
https://doi.org/10.1158/2767-9764.22545009.v1
Autor:
Praveen Sethupathy, Jian Liu, Lola M. Reid, Zhangjie Wang, Paul D. Soloway, Jennifer K. Grenier, Paul R. Munn, Bo Shui, Matt Kanke, Alaa R. Farghli, Jine Li, Adam B. Francisco
Fibrolamellar carcinoma (FLC) is an aggressive liver cancer with no effective therapeutic options. The extracellular environment of FLC tumors is poorly characterized and may contribute to cancer growth and/or metastasis. To bridge this knowledge gap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef009dc79399cb74badf7271ac94e28
https://doi.org/10.1158/2767-9764.c.6550827
https://doi.org/10.1158/2767-9764.c.6550827
Autor:
Adam B. Francisco, Jine Li, Alaa R. Farghli, Matt Kanke, Bo Shui, Paul D. Soloway, Zhangjie Wang, Lola M. Reid, Jian Liu, Praveen Sethupathy
Fibrolamellar carcinoma (FLC) is an aggressive liver cancer with no effective therapeutic options. The extracellular environment of FLC tumors is poorly characterized and may contribute to cancer growth and/or metastasis. To bridge this knowledge gap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38d8045456e351d5c9cebd9bbb68d173
https://doi.org/10.1101/2021.12.07.471610
https://doi.org/10.1101/2021.12.07.471610
Autor:
Seoyeon, Lee, Abigail M, Benvie, Hui Gyu, Park, Roman, Spektor, Blaine, Harlan, J Thomas, Brenna, Daniel C, Berry, Paul D, Soloway
Publikováno v:
Communications biology. 5(1)
Beige adipocytes are induced by cold temperatures or β3-adrenergic receptor (Adrb3) agonists. They create heat through glucose and fatty acid (FA) oxidation, conferring metabolic benefits. The distinct and shared mechanisms by which these treatments
Autor:
Jan Lammerding, Chao-Yuan Chang, Richa Agrawal, Jawuanna McAllister, Seoyeon Lee, Chieh-Ren Hsia, Paul D. Soloway, Julius Judd, Ovais Hasan
Publikováno v:
iScience. 25:104978
SummaryDuring migration, cells often squeeze through small constrictions, requiring extensive deformation. We hypothesized that the nuclear deformation associated with such confined migration could alter chromatin organization and function. Studying
Obesity promotes type 2 diabetes and cardiometabolic pathologies. Vertical sleeve gastrectomy (VSG) is used to treat obesity resulting in long-term weight loss and health improvements that precede weight loss; however, the mechanisms underlying the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6db00f275385d454d234583ec237267
https://doi.org/10.1101/2021.06.22.449469
https://doi.org/10.1101/2021.06.22.449469