Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Paul D. Rainville"'
Autor:
Robert S. Plumb, Lee A. Gethings, Paul D. Rainville, Giorgis Isaac, Robert Trengove, Adam M. King, Ian D. Wilson
Properly implemented, metabolic and lipidomic profiling can provide a deeper understanding of mammalian, plant and bacterial biology. These omics-tools have developed and matured over the last 40-years and are now being deployed to provide valuable i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2addc7cf261cf44ca3160b74fa11775
http://hdl.handle.net/10044/1/103655
http://hdl.handle.net/10044/1/103655
Publikováno v:
Optimization in HPLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02b24be9b24c0bc9a7425f63251b54d1
https://doi.org/10.1002/9783527837489.ch4-5
https://doi.org/10.1002/9783527837489.ch4-5
Publikováno v:
Talanta. 254:124089
The use of vacuum jacketed LC columns (VJC) to minimize on- and post-column band broadening to maximize chromatographic performance has been evaluated as a potential route to improved high throughput (HT) analysis. Here the use of the "VJC" approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2110f817c7b4ec855f2d6b65f4eeaa
https://doi.org/10.1016/j.talanta.2022.124089
https://doi.org/10.1016/j.talanta.2022.124089
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6d271387d6db1d28908338a21b431cd
https://doi.org/10.2139/ssrn.4225414
https://doi.org/10.2139/ssrn.4225414
Autor:
Robert S. Plumb, Giorgis Isaac, Paul D. Rainville, Jason Hill, Lee A. Gethings, Kelly A. Johnson, Joshua Lauterbach, Ian D. Wilson
Publikováno v:
Journal of proteome research. 21(3)
Reversed-phase UHPLC-MS is extensively employed for both the profiling of biological fluids and tissues to characterize lipid dysregulation in disease and toxicological studies. With conventional LC-MS systems the chromatographic performance and thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22f62dbeb762c90e2023634417adfe4
https://pubmed.ncbi.nlm.nih.gov/34968064
https://pubmed.ncbi.nlm.nih.gov/34968064
Autor:
Thomas S. McDonald, Paul D. Rainville, Kelly A. Johnson, Jason F. Hill, Lee A. Gethings, Ian D. Wilson, Robert S. Plumb
In UHPLC, frictional heating from the eluent flowing through the column at pressures of ca. 10-15 Kpsi causes radial diffusion via temperature differences between the center of the column and its walls. Longitudinal dispersion also occurs due to temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62c0651ea02574aff2ad9343fd34c1b
http://hdl.handle.net/10044/1/99180
http://hdl.handle.net/10044/1/99180
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1179
The accurate determination of the pharmacokinetics (PK) of a candidate drug molecule is critical in both drug discovery and development. Over the last 30 years, the sensitivity and selectivity of LC/MS has resulted in it being established as the tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d029e46d158cbf6fc922626cc31b27
https://pubmed.ncbi.nlm.nih.gov/34218093
https://pubmed.ncbi.nlm.nih.gov/34218093
Publikováno v:
Analytical chemistry. 93(2)
We describe a method for the analysis of organic acids, including those of the tricarboxylic acid cycle (TCA cycle), by mixed-mode reversed-phase chromatography, on a CSH Phenyl-Hexyl column, to accomplish mixed-mode anion-exchange separations, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c91ac8e97bf16bb854cb976caa1730f
https://pubmed.ncbi.nlm.nih.gov/33290053
https://pubmed.ncbi.nlm.nih.gov/33290053
Publikováno v:
Journal of Food Composition and Analysis. 100:103824
An LC–MS method was developed for routine determination of lactose in low-lactose and lactose-free dairy products. The lactose was separated on an amide column under an isocratic elution condition. Baseline separation of lactose from common interfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4179ccf04cc674c6b9435db92e786c7
https://doi.org/10.1016/j.jfca.2021.103824
https://doi.org/10.1016/j.jfca.2021.103824
Autor:
Lee A. Gethings, Lauren Mullin, Paul D. Rainville, Robert D. Trengove, Robert S. Plumb, Adam King, Ian D. Wilson, Giorgis Isaac
The incorporation of ion mobility (IM) into LC-MS analysis has been demonstrated to result in the generation of superior quality MS and MS/MS spectral data as well as providing enhanced resolution in the IM dimension based on lipid class. Here a sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc67b35e25caffee713bcae2c5ae3fa1
http://hdl.handle.net/10044/1/77671
http://hdl.handle.net/10044/1/77671