Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Paul D. Ponath"'
Autor:
Edith A Perez, Andrew Luo, Anthony Lucas, Han K Kim, Paul D Ponath, Katelynn A McEachin, Karla A Henning, Shelley E Ackerman, Steven J Chapin, Michael N Alonso, Cecelia I Pearson, David Omstead
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/3dd5d80f575f46cfba2236317430d3dc
Autor:
Matthew Zhou, William Mallet, Romas Kudirka, Han K Kim, Justin Monnier, Chi-Ling Fu, Jennifer E Melrose, Hung Dao, Paul D Ponath, Katelynn A McEachin, David T Omstead, Cindy Kreder, Stefan Chun, Ying Yueh Lee, Rachel Grgich, Tracey J Lin, Joshua A Walker, Karla A Henning, Shelley E Ackerman, Diane Carrera, Steven J Chapin, Dowdy Jackson, Changshou Gao, Michael N Alonso
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/30e7900b97ae4dd8a324a8032d05c871
Autor:
Paul D. Ponath, Michael Paglia, Louis Vaickus, Masahide Tone, Reema Gulati, Michael Rosenzweig, Michael Slavonic, Herman Waldmann, Jose F. Ponte, Adam O'Shea
Publikováno v:
Immunology. 130:231-242
Adjuvants, including antibodies to tumour necrosis factor receptor superfamily members, augment immune responses. One member of this family, glucocorticoid-induced tumour necrosis factor receptor (GITR), is expressed at low levels on naive/resting T
Autor:
Victoria E. L. Stubbs, Ian Sabroe, Paul D. Ponath, Louise A. Jopling, Timothy J. Williams, Philip M. Murphy, Annelies Jorritsma, Georgina Xanthou, James E. Pease
Publikováno v:
European Journal of Immunology. 35:1301-1310
The chemokine receptor CCR3 regulates the chemotaxis of leukocytes implicated in allergic disease, such as eosinophils. Incubation of eosinophils with CCL11, CCL13 or CCL5 resulted in a rapid decrease of cell-surface CCR3 which was replicated using C
Autor:
Robert J. B. Nibbs, Antal Rot, Alison Henderson, Paul D. Ponath, Shixin Qin, Gerard J. Graham, Ernst Kriehuber, David Parent, Dontscho Kerjaschki, Dieter Maurer, John D. Campbell
Publikováno v:
The American Journal of Pathology. 158:867-877
The lymphatic vessels (lymphatics) play an important role in channeling fluid and leukocytes from the tissues to the secondary lymphoid organs. In addition to driving leukocyte egress from blood, chemokines have been suggested to contribute to leukoc
Autor:
Fuad M. Baroody, Lisa A. Beck, Syed Shahabuddin, Mark C. Liu, James R. Plitt, Paul D. Ponath, Mary Brummet, Cristiana Stellato
Publikováno v:
The Journal of Immunology. 166:1457-1461
Chemokine-induced eosinophil chemotaxis is mediated primarily through the C-C chemokine receptor, CCR3. We have now detected CCR3 immunoreactivity on epithelial cells in biopsies of patients with asthma and other respiratory diseases. CCR3 mRNA was d
Autor:
Brian A. Zabel, Arthur I. Roberts, Maria Zovko, Paul D. Ponath, Li-Li Yang, Christina M. Parker, Ellen C. Ebert, Dulce Soler, William W. Agace, David P. Andrew, Heidi Heath, Nasim Kassam, Eugene C. Butcher, David Parent, Shixin Qin, Gregory J. LaRosa, James Campbell
Publikováno v:
The Journal of Experimental Medicine
TECK (thymus-expressed chemokine), a recently described CC chemokine expressed in thymus and small intestine, was found to mediate chemotaxis of human G protein-coupled receptor GPR-9-6/L1.2 transfectants. This activity was blocked by anti-GPR-9-6 mo
Autor:
Ian Sabroe, Adele Hartnell, Louise A. Jopling, Sandra Bel, Paul D. Ponath, James E. Pease, Paul D. Collins, Timothy J. Williams
Publikováno v:
The Journal of Immunology. 162:2946-2955
To investigate eosinophil stimulation by chemokines we developed a sensitive assay of leukocyte shape change, the gated autofluorescence/forward scatter assay. Leukocyte shape change responses are mediated through rearrangements of the cellular cytos
Autor:
Ian Sabroe, Dolores M. Conroy, Norma P. Gerard, You Li, Paul D. Collins, Theodore W. Post, Peter J. Jose, Timothy J. Williams, Craig J. Gerard, Paul D. Ponath
Publikováno v:
The Journal of Immunology. 161:6139-6147
Certain C-C chemokines, signaling via the eotaxin receptor C-C chemokine receptor-3 (CCR3), are thought to be central mediators of eosinophil accumulation in allergic inflammation. To investigate the role of CCR3 in vivo, we cloned the guinea pig eot
Publikováno v:
ResearcherID
Chemokines are widely hypothesized to stimulate firm adhesion of leukocytes on endothelium in shear flow. Thus far, this has been demonstrated experimentally for exogenously added chemoattractants, but not for those released by endothelium. We found