Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Paul D. Iordache"'
Autor:
Stefania Benonisdottir, Asmundur Oddsson, Agnar Helgason, Ragnar P. Kristjansson, Gardar Sveinbjornsson, Arna Oskarsdottir, Gudmar Thorleifsson, Olafur B. Davidsson, Gudny A. Arnadottir, Gerald Sulem, Brynjar O. Jensson, Hilma Holm, Kristjan F. Alexandersson, Laufey Tryggvadottir, G. Bragi Walters, Sigurjon A. Gudjonsson, Lucas D. Ward, Jon K. Sigurdsson, Paul D. Iordache, Michael L. Frigge, Thorunn Rafnar, Augustine Kong, Gisli Masson, Hannes Helgason, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Patrick Sulem, Kari Stefansson
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Adult height has a strong genetic component and is highly heritable. Here the authors whole-genome sequence 8,453 Icelanders and find novel parent-of-origin derived associations in IGF2-H19 and DLK1-MEG3.
Externí odkaz:
https://doaj.org/article/601995f6997a4f46bd7bff4330856811
Autor:
Viorel Jinga, Dana Mateș, Violeta Calota, Ioan Nicolae Mateș, Irma Eva Csiki, Agripina Rașcu, Marina Ruxandra Oțelea, Nicoleta Suciu, Angelica Voinoiu, Andrei Manolescu, Ștefan Alexandru Rașcu, Cătălin Alexandru Staicu, Paul D. Iordache
Publikováno v:
Romanian Journal of Occupational Medicine. 70:38-45
Several occupational carcinogens (arsenic, cadmium) and industries (rubber production) have been associated with prostate cancer risk but most of the data are from studies conducted on screened populations. Here we explored this association in Romani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9e7f503dc14bca0d162f8ee338c64ab
https://doi.org/10.2478/rjom-2019-0006
https://doi.org/10.2478/rjom-2019-0006
Autor:
Cristian Toma, Viorel Jinga, Paul D. Iordache, Titus Valentin Grigorean, Dumitru Cristinel Badiu, George Daniel Radavoi, Viorica Radoi, Radu Ursu, Mihaela Mandu, Cristian Sorin Sima, Bogdan Braticevici, Razvan Danau, Stefan Rascu
Publikováno v:
ROMANIAN BIOTECHNOLOGICAL LETTERS. 24:100-107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53cad11a7aa64283b0a48f1c7792cdd9
https://doi.org/10.25083/rbl/24.1/100.107
https://doi.org/10.25083/rbl/24.1/100.107
Autor:
Bjarni Gunnarsson, Viorel Jinga, Angelica Voinoiu, Hrefna Johannsdottir, Stefan Rascu, Stefania Benonisdottir, Violeta Calota, Sorin Cristian Sima, Jon G. Jonasson, Razvan Danau, Dana Mates, Viorica Radoi, Daniel Badescu, Radu Ursu, Camelia Nicolae, Gudny A. Arnadottir, Cătălin Alexandru Staicu, Bjarni V. Halldorsson, Thorunn Rafnar, Paul D. Iordache, Aslaug Jonasdottir, Asgeir Sigurdsson, Kari Stefansson, Mihai Dobra, Irma Eva Csiki, Hannes P. Eggertsson, Sigrun Kristjansdottir, Ioan Nicolae Mates, Mariana Jinga, Louise le Roux, Andrei Manolescu, Brynjar O. Jensson, Nicoleta Suciu, Daniel Radavoi, Gabriel Rosoga, Patrick Sulem
Publikováno v:
Journal of Cellular and Molecular Medicine
Publisher's version (útgefin grein)
Two familial forms of colorectal cancer (CRC), Lynch syndrome (LS) and familial adenomatous polyposis (FAP), are caused by rare mutations in DNA mismatch repair genes (MLH1, MSH2, MSH6, PMS2) and the genes AP
Two familial forms of colorectal cancer (CRC), Lynch syndrome (LS) and familial adenomatous polyposis (FAP), are caused by rare mutations in DNA mismatch repair genes (MLH1, MSH2, MSH6, PMS2) and the genes AP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb71a9cd3010c7f038a6df677219bc6
https://doi.org/10.1111/jcmm.13881
https://doi.org/10.1111/jcmm.13881
Autor:
Gudny A. Arnadottir, Thorunn Rafnar, Hannes Helgason, Michael L. Frigge, Gardar Sveinbjornsson, Daniel F. Gudbjartsson, Patrick Sulem, Lucas D. Ward, Stefania Benonisdottir, Paul D. Iordache, Ragnar P. Kristjansson, Augustine Kong, Gisli Masson, Sigurjon A. Gudjonsson, G. Bragi Walters, Arna Oskarsdottir, Kristjan F. Alexandersson, Hilma Holm, Olafur B. Davidsson, Jon K. Sigurdsson, Gerald Sulem, Laufey Tryggvadottir, Unnur Thorsteinsdottir, Gudmar Thorleifsson, Asmundur Oddsson, Kari Stefansson, Brynjar O. Jensson, Agnar Helgason
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications
Nature Communications
Adult height is a highly heritable trait. Here we identified 31.6 million sequence variants by whole-genome sequencing of 8,453 Icelanders and tested them for association with adult height by imputing them into 88,835 Icelanders. Here we discovered 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3c54317ab63f09e2de08f3ec9f703a
https://doi.org/10.1038/ncomms13490
https://doi.org/10.1038/ncomms13490
Autor:
Sigurgeir Olafsson, Srdjan Djurovic, Daníel F. Guðbjartsson, Bjarni Gunnarsson, Ina Giegling, Hannes Helgason, Thomas Espeseth, Gyða Björnsdóttir, Guðrún A. Jónsdóttir, Augustine Kong, Paul D. Iordache, Snaedis Kristmundsdottir, Jonas G. Halldorsson, Kari Stefansson, Unnur Thorsteinsdottir, Birte Kehr, Kjetil Sundet, Ingrid Melle, Hreinn Stefansson, Berglind Stefánsdóttir, Patrick Sulem, Michael L. Frigge, Omar Gustafsson, Sunna Arnarsdottir, Dan Rujescu, Guðmar Þorleifsson, Bettina Konte, Annette M. Hartmann, Ole A. Andreassen, Bjarni V. Halldorsson, Ulrich Ettinger
Publikováno v:
Scientific Reports
Only a few common variants in the sequence of the genome have been shown to impact cognitive traits. Here we demonstrate that polygenic scores of educational attainment predict specific aspects of childhood cognition, as measured with IQ. Recently, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd9f0f7551cd877c653f0552da85040b
https://pubmed.ncbi.nlm.nih.gov/27811963
https://pubmed.ncbi.nlm.nih.gov/27811963
Autor:
Bjarni A. Agnarsson, Hrefna Johannsdottir, Thorunn Rafnar, Gisli Masson, Katja K.H. Aben, Agnar Helgason, Simon N. Stacey, Hannes Helgason, Gudmundur V. Einarsson, Daniel F. Gudbjartsson, William J. Catalona, Phillip R. Cooper, Jon G. Jonasson, Rosa B. Barkardottir, Eirikur Jonsson, Ichiro Okamoto, Sigurjon A. Gudjonsson, Paul D. Iordache, Anna M. Kristinsdottir, Brian T. Helfand, Aslaug Jonasdottir, Augustine Kong, Viorel Jinga, Florian Zink, Bjarni V. Halldorsson, Jenny L Donovan, Freddie C. Hamdy, Asgeir Sigurdsson, Kristrun R. Benediktsdottir, Laufey Tryggvadottir, Olafur T. Magnusson, Gudmar Thorleifsson, Julius Gudmundsson, Ruben Cremers, Lambertus A. Kiemeney, Angeles Panadero, Birte Kehr, David E. Neal, Jose I. Mayordomo, Kari Stefansson, Unnur Thorsteinsdottir, Ioan Nicolae Mates, Sita H. Vermeulen, Patrick Sulem
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, 25, 1008-18
Stacey, S N, Kehr, B, Gudmundsson, J, Zink, F, Jonasdottir, A, Gudjonsson, S A, Sigurdsson, A, Halldorsson, B V, Agnarsson, B A, Benediktsdottir, K R, Aben, K K H, Vermeulen, S H, Cremers, R G, Panadero, A, Helfand, B T, Cooper, P R, Donovan, J L, Hamdy, F C, Jinga, V, Okamoto, I, Jonasson, J G, Tryggvadottir, L, Johannsdottir, H, Kristinsdottir, A M, Masson, G, Magnusson, O T, Iordache, P D, Helgason, A, Helgason, H, Sulem, P, Gudbjartsson, D F, Kong, A, Jonsson, E, Barkardottir, R B, Einarsson, G V, Rafnar, T, Thorsteinsdottir, U, Mates, I N, Neal, D E, Catalona, W J, Mayordomo, J I, Kiemeney, L A, Thorleifsson, G & Stefansson, K 2016, ' Insertion of an SVA-E retrotransposon into the CASP8 gene is associated with protection against prostate cancer ', Human Molecular Genetics, vol. 25, no. 5, pp. 1008-1018 . https://doi.org/10.1093/hmg/ddv622
Human Molecular Genetics, 25, 5, pp. 1008-18
Human Molecular Genetics, 25, 1008-18
Stacey, S N, Kehr, B, Gudmundsson, J, Zink, F, Jonasdottir, A, Gudjonsson, S A, Sigurdsson, A, Halldorsson, B V, Agnarsson, B A, Benediktsdottir, K R, Aben, K K H, Vermeulen, S H, Cremers, R G, Panadero, A, Helfand, B T, Cooper, P R, Donovan, J L, Hamdy, F C, Jinga, V, Okamoto, I, Jonasson, J G, Tryggvadottir, L, Johannsdottir, H, Kristinsdottir, A M, Masson, G, Magnusson, O T, Iordache, P D, Helgason, A, Helgason, H, Sulem, P, Gudbjartsson, D F, Kong, A, Jonsson, E, Barkardottir, R B, Einarsson, G V, Rafnar, T, Thorsteinsdottir, U, Mates, I N, Neal, D E, Catalona, W J, Mayordomo, J I, Kiemeney, L A, Thorleifsson, G & Stefansson, K 2016, ' Insertion of an SVA-E retrotransposon into the CASP8 gene is associated with protection against prostate cancer ', Human Molecular Genetics, vol. 25, no. 5, pp. 1008-1018 . https://doi.org/10.1093/hmg/ddv622
Human Molecular Genetics, 25, 5, pp. 1008-18
Contains fulltext : 172827.pdf (Publisher’s version ) (Open Access) Transcriptional and splicing anomalies have been observed in intron 8 of the CASP8 gene (encoding procaspase-8) in association with cutaneous basal-cell carcinoma (BCC) and linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1454f89186ff62410f37a686875c29f
https://pubmed.ncbi.nlm.nih.gov/26740556
https://pubmed.ncbi.nlm.nih.gov/26740556
Autor:
Bjarni V. Halldorsson, Radu Ursu, Viorel Jinga, Andrei Manolescu, Paul D. Iordache, Dana Mates
Publikováno v:
Cancer Research. 77:1324-1324
In the present study we investigated for the first time the profile of common prostate cancer risk variants in an unscreened Romanian population. The study population consisted of 990 unrelated histopathologically confirmed prostate cancer (PCa) case
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f25170014a788fdaa876d5a6216c186e
https://doi.org/10.1158/1538-7445.am2017-1324
https://doi.org/10.1158/1538-7445.am2017-1324