Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Paul D. Hoeprich"'
Autor:
Dina R. Weilhammer, Alexis D. Dunkle, Tyler Boone, Sean F. Gilmore, Mark Khemmani, Sandra K. G. Peters, Paul D. Hoeprich, Nicholas O. Fischer, Craig D. Blanchette, Adam Driks, Amy Rasley
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Subunit vaccines are theoretically safe and easy to manufacture but require effective adjuvants and delivery systems to yield protective immunity, particularly at critical mucosal sites such as the lung. We investigated nanolipoprotein particles (NLP
Externí odkaz:
https://doaj.org/article/ca91e8ee57e54aeda6984465ee70cda7
Autor:
Craig D. Blanchette, Richard Law, W. Henry Benner, Joseph B. Pesavento, Jenny A. Cappuccio, Vicki Walsworth, Edward A. Kuhn, Michele Corzett, Brett A. Chromy, Brent W. Segelke, Matthew A. Coleman, Graham Bench, Paul D. Hoeprich, Todd A. Sulchek
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 7, Pp 1420-1430 (2008)
Self-assembly of purified apolipoproteins and phospholipids results in the formation of nanometer-sized lipoprotein complexes, referred to as nanolipoprotein particles (NLPs). These bilayer constructs are fully soluble in aqueous environments and hol
Externí odkaz:
https://doaj.org/article/c73175892234465182736f2559d216dd
Autor:
Matthew A Coleman, Jenny A Cappuccio, Craig D Blanchette, Tingjuan Gao, Erin S Arroyo, Angela K Hinz, Feliza A Bourguet, Brent Segelke, Paul D Hoeprich, Thomas Huser, Ted A Laurence, Vladimir L Motin, Brett A Chromy
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150166 (2016)
Yersinia pestis enters host cells and evades host defenses, in part, through interactions between Yersinia pestis proteins and host membranes. One such interaction is through the type III secretion system, which uses a highly conserved and ordered co
Externí odkaz:
https://doaj.org/article/ce20e916630041188cd3ee34a7e0cc71
Autor:
Nicholas O. Fischer, Paul D. Hoeprich, Craig D. Blanchette, Tyler Boone, Sean F. Gilmore, Sandra K. G. Peters, Adam Driks, Amy Rasley, Alexis Dunkle, Dina R. Weilhammer, Mark Khemmani
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Subunit vaccines are theoretically safe and easy to manufacture but require effective adjuvants and delivery systems to yield protective immunity, particularly at critical mucosal sites such as the lung. We investigated nanolipoprotein particles (NLP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6078625d22f4591d69cd0f350ff5af2e
http://europepmc.org/articles/PMC7344197
http://europepmc.org/articles/PMC7344197
Autor:
Nicholas O Fischer, Craig D Blanchette, Brent W Segelke, Michele Corzett, Brett A Chromy, Edward A Kuhn, Graham Bench, Paul D Hoeprich
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11643 (2010)
BACKGROUND: Nanolipoprotein particles (NLPs) are discoidal, nanometer-sized particles comprised of self-assembled phospholipid membranes and apolipoproteins. NLPs assembled with human apolipoproteins have been used for myriad biotechnology applicatio
Externí odkaz:
https://doaj.org/article/1d466b8345694c71834ad82dacff380c
Autor:
Alexis Dunkle, Adam Driks, Dina R. Weilhammer, Craig D. Blanchette, Tyler Boone, Amy Rasley, Paul D. Hoeprich, Nicholas O. Fischer, Michele Corzett, Doerte Lehmann
Publikováno v:
Vaccine. 35:1475-1481
To address the need for vaccine platforms that induce robust cell-mediated immunity, we investigated the potential of utilizing self-assembling biologic nanolipoprotein particles (NLPs) as an antigen and adjuvant delivery system to induce antigen-spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3d5c741692c980452fba8aa4cfca303
https://doi.org/10.1016/j.vaccine.2017.02.004
https://doi.org/10.1016/j.vaccine.2017.02.004
Autor:
Michael Mallozzi, Amy Rasley, Brian M. Thompson, Dörte Lehmann, Adam Driks, Paul D. Hoeprich, George C. Stewart, Mark Khemmani, Alexander Nelson, Tyler Boone, Alexis Dunkle
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
mBio
mBio, Vol 9, Iss 6, p e01166-18 (2018)
mBio
mBio, Vol 9, Iss 6, p e01166-18 (2018)
This work dramatically improves our understanding of the assembly of the outermost layer of the B. anthracis spore, the exosporium, a layer that encases spores from many bacterial species and likely plays important roles in the spore’s interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9583a3429c60ffeb5bc4dc8eb523fa21
https://doi.org/10.1128/mbio.01166-18
https://doi.org/10.1128/mbio.01166-18
Autor:
Teresa de los Santos, Paul D. Hoeprich, Elizabeth Rieder, Thomas G. Burrage, Luis L. Rodriguez, Fayna Diaz-San Segundo, Devendra K. Rai, Elizabeth A. Schafer
Publikováno v:
Virology. 495:136-147
Here, we engineered two FMD viruses with histidine residues inserted into or fused to the FMDV capsid. Both 6xHis viruses exhibited growth kinetics, plaque morphologies and antigenic characteristics similar to wild-type virus. The 6xHis tag allowed o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788293f305ecd41ce029a646184aef75
https://doi.org/10.1016/j.virol.2016.04.027
https://doi.org/10.1016/j.virol.2016.04.027
Autor:
Nicholas O. Fischer, Michele Corzett, Amy Rasley, Paul D. Hoeprich, Mona H. Hwang, Craig D. Blanchette
Publikováno v:
Journal of the American Chemical Society. 135:2044-2047
Subunit antigen-based vaccines can provide a number of important benefits over traditional vaccine candidates, such as overall safety. However, because of the inherently low immunogenicity of these antigens, methods for colocalized delivery of antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d0f5d723df7d9f84e4dd552119cc30
https://doi.org/10.1021/ja3063293
https://doi.org/10.1021/ja3063293
Autor:
Matthew A. Coleman, Tingjuan Gao, Erins Arroyo, Ted A. Laurence, Feliza Bourguet, Vladimir L. Motin, Paul D. Hoeprich, Brett A. Chromy, Angela K. Hinz, Jenny A. Cappuccio, Thomas R Huser, Craig D. Blanchette, Brent W. Segelke
Publikováno v:
PloS one, vol 11, iss 3
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0150166 (2016)
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0150166 (2016)
Yersinia pestis enters host cells and evades host defenses, in part, through interactions between Yersinia pestis proteins and host membranes. One such interaction is through the type III secretion system, which uses a highly conserved and ordered co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5cb5fd63837348b40c3d58e0e1b7ba
https://escholarship.org/uc/item/7cb1v6jt
https://escholarship.org/uc/item/7cb1v6jt
