Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Paul D. Doodes"'
Autor:
Alison Finnegan, Keith M. Hamel, Katalin Mikecz, Tibor T. Glant, Paul D. Doodes, Yoichiro Iwakura, Yumei Wang, Yanxia Cao, Rachel Rodeghero
Publikováno v:
The Journal of Immunology. 184:1552-1559
The contribution of the proinflammatory cytokines IFN-gamma and IL-17 to the pathogenesis of experimental arthritis is controversial. In proteoglycan (PG)-induced arthritis (PGIA), severe arthritis is dependent on the production of IFN-gamma, whereas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7644805af9490effd4421f613e78a15c
https://doi.org/10.4049/jimmunol.0902907
https://doi.org/10.4049/jimmunol.0902907
Autor:
Yanxia Cao, Yumei Wang, Keith M. Hamel, Alison Finnegan, Tamás Kobezda, Paul D. Doodes, Rachel Rodeghero
Publikováno v:
Arthritis & Rheumatism. 60:2945-2953
Rheumatoid arthritis (RA) is a chronic, progressive autoimmune disease characterized by joint infiltration by several populations of leukocytes including T cells, B cells, macrophages and neutrophils (1). These infiltrating cells, in collaboration wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2238898a4404220928d182b5cf879e
https://doi.org/10.1002/art.24842
https://doi.org/10.1002/art.24842
Autor:
Paul D. Doodes, Yoichiro Iwakura, Yumei Wang, Alison Finnegan, Balint Farkas, Keith M. Hamel, Yanxia Cao
Publikováno v:
Scopus-Elsevier
IL-17 is the hallmark cytokine for the newly identified subset of Th cells, Th17. Th17 cells are important instigators of inflammation in several models of autoimmune disease; in particular, collagen induced arthritis (CIA) and experimental autoimmun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0583ccb21ecc65e21f3f7c928211060e
https://doi.org/10.4049/jimmunol.181.1.329
https://doi.org/10.4049/jimmunol.181.1.329
Publikováno v:
The Journal of Immunology. 180:922-930
IL-27 is the newest member of the cytokine family comprised of IL-12 and IL-23. IL-27 was originally described as a cytokine that along with IL-12 induces the differentiation of naive precursor T cells into Th1 effector cells. This activity has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb9bf08a6be26be1225b1d5ce134c8e
https://doi.org/10.4049/jimmunol.180.2.922
https://doi.org/10.4049/jimmunol.180.2.922
Publikováno v:
The Journal of Immunology. 179:5109-5116
Depletion of B cells in rheumatoid arthritis is therapeutically efficacious. Yet, the mechanism by which B cells participate in the inflammatory process is unclear. We previously demonstrated that Ag-specific B cells have two important functions in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f37b7cfc5ea0d36a18b28f2716ddec
https://doi.org/10.4049/jimmunol.179.8.5109
https://doi.org/10.4049/jimmunol.179.8.5109
Autor:
Paul D. Doodes, Alison Finnegan
Publikováno v:
Arthritis & Rheumatism. 58:3283-3285
T cells have been implicated in the pathogenesis of rheumatoid arthritis (RA) on the basis of an observed genetic association with MHC class II alleles, the high numbers of T cells in the inflamed synovial tissues in RA, and the requirement for T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89a572f7b892e079fae633bed0a6c537
https://doi.org/10.1002/art.23952
https://doi.org/10.1002/art.23952
Autor:
Yumei Wang, Balint Farkas, Paul D. Doodes, Marilyn R. Kehry, Yanxia Cao, Robert Dunn, Keith M. Hamel, Alison Finnegan, Jeffrey Martinson
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 180(7)
B cells have been implicated in the pathogenesis of rheumatoid arthritis (RA) since the discovery of RA as an autoimmune disease. There is renewed interest in B cells in RA based on the clinical efficacy of B cell depletion therapy in RA patients. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d62dc986ce8893b4a94d59fa375c7f
https://pubmed.ncbi.nlm.nih.gov/18354225
https://pubmed.ncbi.nlm.nih.gov/18354225
Autor:
Yanxia Cao, Marilyn R. Kehry, Paul D. Doodes, Alison Finnegan, Keith M. Hamel, Robert Dunn, Yumei Wang
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74f1b9f1e4b7a33cffc7aa303be596ba
https://doi.org/10.1096/fasebj.22.1_supplement.1074.13
https://doi.org/10.1096/fasebj.22.1_supplement.1074.13
Autor:
Mark J. Shlomchik, Tibor T. Glant, Paul D. Doodes, Shannon K. O’Neill, Yanxia Cao, Alison Finnegan
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 174(6)
B cells play an important role in rheumatoid arthritis, but whether they are required as autoantibody-producing cells as well as APCs has not been determined. We assessed B cell autoantibody and APC functions in a murine model of autoimmune arthritis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f748c8d0147a0c86f2196fafebcd43
https://pubmed.ncbi.nlm.nih.gov/15749919
https://pubmed.ncbi.nlm.nih.gov/15749919
Autor:
Doodes, Paul D., Yanxia Cao, Hamel, Keith M., Yumei Wang, Rodeghero, Rachel L., Kobezda, Tamas, Finnegan, Alison
Publikováno v:
Arthritis & Rheumatism; Oct2009, Vol. 60 Issue 10, p2945-2953, 9p