Výsledky vyhledávání - "Paul D. Cao"

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Figure S4 from Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells

Autor: Don X. Nguyen, Malaiyalam Mariappan, Paul D. Cao, Minghui Zhao, Zongzhi Liu, Gary W. Cline, Anna Arnal-Estapé, Wesley L. Cai, Sally J. Adua, Alexandra E. Albert

This figure shows that ASNS mediates protein translation during amino acid deprivation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15356a23ce1ab1d69525e1eb42f4a183
https://doi.org/10.1158/1541-7786.22513200.v1

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Figure S3 from Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells

Autor: Don X. Nguyen, Malaiyalam Mariappan, Paul D. Cao, Minghui Zhao, Zongzhi Liu, Gary W. Cline, Anna Arnal-Estapé, Wesley L. Cai, Sally J. Adua, Alexandra E. Albert

Thsi figure further describes the molecular effects of ATF4 inhibition and ISRIB during asparagine starvation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad9addbe0b70ac1ca219daa9546fee5
https://doi.org/10.1158/1541-7786.22513203

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Supplementary Table 2 from Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells

Autor: Don X. Nguyen, Malaiyalam Mariappan, Paul D. Cao, Minghui Zhao, Zongzhi Liu, Gary W. Cline, Anna Arnal-Estapé, Wesley L. Cai, Sally J. Adua, Alexandra E. Albert

Supplementary Table 2 shows differential gene expression in LUAD cells treated with ISRIB during asparagine deprivation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd874e05f1d07c112067fa22289a4fa
https://doi.org/10.1158/1541-7786.22513179

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Figure S1 from Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells

Autor: Don X. Nguyen, Malaiyalam Mariappan, Paul D. Cao, Minghui Zhao, Zongzhi Liu, Gary W. Cline, Anna Arnal-Estapé, Wesley L. Cai, Sally J. Adua, Alexandra E. Albert

This figure demonstrates that the ISR is activated in diverse molecular subtypes and stages of LUAD and can be inhibited by ISRIB.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31af6a877babf150c6eb5bfda6da9c78
https://doi.org/10.1158/1541-7786.22513209.v1

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Figure S2 from Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells

Autor: Don X. Nguyen, Malaiyalam Mariappan, Paul D. Cao, Minghui Zhao, Zongzhi Liu, Gary W. Cline, Anna Arnal-Estapé, Wesley L. Cai, Sally J. Adua, Alexandra E. Albert

This figure describes the effects of ISRIB on the adaptive proliferation and motility of LUAD cells under amino acid stress.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567db21dd0f8e564322c23fb653df761
https://doi.org/10.1158/1541-7786.22513206.v1

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Figure S7 from Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells

Autor: Don X. Nguyen, Malaiyalam Mariappan, Paul D. Cao, Minghui Zhao, Zongzhi Liu, Gary W. Cline, Anna Arnal-Estapé, Wesley L. Cai, Sally J. Adua, Alexandra E. Albert

This figure shows how dietary asparagine limitation combined with ISR inhibition delays LUAD growth in vivo.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a74a18759728641e9f9d541c963466f
https://doi.org/10.1158/1541-7786.22513191.v1

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Figure S6 from Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells

Autor: Don X. Nguyen, Malaiyalam Mariappan, Paul D. Cao, Minghui Zhao, Zongzhi Liu, Gary W. Cline, Anna Arnal-Estapé, Wesley L. Cai, Sally J. Adua, Alexandra E. Albert

This figure shows that Cyclin B1 protein synthesis is regulated by ASNS in LUAD cells under stress.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b550f8a713c57f3896b16f77faf3d2a
https://doi.org/10.1158/1541-7786.22513194.v1

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Figure S5 from Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells

Autor: Don X. Nguyen, Malaiyalam Mariappan, Paul D. Cao, Minghui Zhao, Zongzhi Liu, Gary W. Cline, Anna Arnal-Estapé, Wesley L. Cai, Sally J. Adua, Alexandra E. Albert

This figure shows that ASNS-mediated protein translation is sufficient for adaptive cell proliferation and migration.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186cf323d30f2473a418df61347cb3c7
https://doi.org/10.1158/1541-7786.22513197

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Supplementary Table 4 from Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells

Autor: Don X. Nguyen, Malaiyalam Mariappan, Paul D. Cao, Minghui Zhao, Zongzhi Liu, Gary W. Cline, Anna Arnal-Estapé, Wesley L. Cai, Sally J. Adua, Alexandra E. Albert

Supplementary Table 4 list the results from Reverse phase protein array analysis of LUAD cells treated with ISRIB during asparagine deprivation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417571ec9ba5b19327f73a6e4351ca79
https://doi.org/10.1158/1541-7786.22513170.v1

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Supplementary Data legends from Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells

Autor: Don X. Nguyen, Malaiyalam Mariappan, Paul D. Cao, Minghui Zhao, Zongzhi Liu, Gary W. Cline, Anna Arnal-Estapé, Wesley L. Cai, Sally J. Adua, Alexandra E. Albert

This file list contains the legends for supplementary Figures and tables.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e01c719801025885f775cb15fb0b9d
https://doi.org/10.1158/1541-7786.22513188.v1

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