Zobrazeno 1 - 10
of 922
pro vyhledávání: '"Paul D. Brown"'
Autor:
David M. Routman, Ignacio Jusue-Torres, Paul D. Brown, Daniel M. Trifiletti, Sujay A. Vora, Desmond A. Brown, Ian F. Parney, Terry C. Burns, Elizabeth Yan
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background and Objectives Almost one third of cancer patients in the United States will develop brain metastases on an annual basis. Surgical resection is indicated in the setting of brain metastases for reasons, such as maximizing local con
Externí odkaz:
https://doaj.org/article/3a8126d4f2ad4872bf4d30a5d6f8ce1c
Autor:
Joseph A. Miccio, Zizhong Tian, Sean S. Mahase, Christine Lin, Serah Choi, Brad E. Zacharia, Jason P. Sheehan, Paul D. Brown, Daniel M. Trifiletti, Joshua D. Palmer, Ming Wang, Nicholas G. Zaorsky
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-12 (2024)
Abstract Background Brain metastases (BM) affect clinical management and prognosis but limited resources exist to estimate BM risk in newly diagnosed cancer patients. Additionally, guidelines for brain MRI screening are limited. We aimed to develop a
Externí odkaz:
https://doaj.org/article/f578ab728bf348cf95904caea5fe65be
Autor:
Ugur Sener, Mason Webb, William G. Breen, Bryan J. Neth, Nadia N. Laack, David Routman, Paul D. Brown, Anita Mahajan, Kelsey Frechette, Arkadiusz Z. Dudek, Svetomir N. Markovic, Matthew S. Block, Robert R. McWilliams, Anastasios Dimou, Lisa A. Kottschade, Heather N. Montane, Sani H. Kizilbash, Jian L. Campian
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 7, Iss 1, Pp 1-6 (2024)
Introduction Proton craniospinal irradiation (pCSI) is a treatment option for leptomeningeal disease (LMD), which permits whole neuroaxis treatment while minimizing toxicity. Despite this, patients inevitably experience progression. Adding systemic t
Externí odkaz:
https://doaj.org/article/e46cf582bd95407aa5330e020924b4ae
Autor:
Benjamin L. Weare, Sean Hoggett, William J. Cull, Stephen P. Argent, Andrei N. Khlobystov, Paul D. Brown
Publikováno v:
IUCrData, Vol 9, Iss 6, p x240612 (2024)
The crystal structure of the title compound was determined at 120 K. It crystallizes in the triclinic space group P\overline{1} with four independent molecules in the asymmetric unit. In the crystal, each symmetry-unique molecule forms π–π stacks
Externí odkaz:
https://doaj.org/article/a5b2761466fe473b82d82217e1d96fee
Autor:
Kelsey M. Frechette, William G. Breen, Paul D. Brown, Ugur T. Sener, Lauren M. Webb, David M. Routman, Nadia N. Laack, Anita Mahajan, Eric J. Lehrer
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1792 (2024)
Leptomeningeal disease (LMD) is a devastating sequelae of metastatic spread that affects approximately 5% of cancer patients. The incidence of LMD is increasing due to advancements in systemic therapy and enhanced detection methods. The purpose of th
Externí odkaz:
https://doaj.org/article/bcf4ca29db60462c8c873544ff797fa1
Autor:
Jesús Molinar‐Díaz, John Luke Woodliffe, Benjamin Milborne, Lauren Murrell, Md Towhidul Islam, Elisabeth Steer, Nicola Weston, Nicola A. Morley, Paul D. Brown, Ifty Ahmed
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 11, Pp n/a-n/a (2023)
Abstract Highly porous, ferromagnetic glass‐ceramic P40‐Fe3O4 microspheres (125–212 µm) with enhanced cytocompatibility have been manufactured for the first time via a facile, rapid, single‐stage flame spheroidization process. Dispersions of
Externí odkaz:
https://doaj.org/article/f405dde7b3974be088eb27c7a0cd8f41
Autor:
Roman Kowalchuk, Trey C. Mullikin, William Breen, Hunter C. Gits, Marcus Florez, Brian De, William S. Harmsen, Peter Sean Rose, Brittany L. Siontis, Brian A. Costello, Jonathan M. Morris, John J. Lucido, Kenneth R. Olivier, Brad Stish, Nadia N. Laack, Sean Park, Dawn Owen, Amol J. Ghia, Paul D. Brown, Kenneth Wing Merrell
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThough metastasis-directed therapy (MDT) has the potential to improve overall survival (OS), appropriate patient selection remains challenging. We aimed to develop a model predictive of OS to refine patient selection for clinical trials and
Externí odkaz:
https://doaj.org/article/120bcacd9bb144df985c7ad3e18bec70
Autor:
Christopher D. Abraham, MD, Stephanie L. Pugh, PhD, Joseph A. Bovi, MD, Vinai Gondi, MD, Minesh P. Mehta, MD, Tammie Benzinger, MD, Christopher J. Owen, MS, Simon S. Lo, MD, Vijayananda Kundapur, MD, Paul D. Brown, MD, Alexander Y. Sun, MD, Steven P. Howard, MD, Albert S. DeNittis, MD, Clifford G. Robinson, MD, Lisa A. Kachnic, MD
Publikováno v:
Advances in Radiation Oncology, Vol 7, Iss 6, Pp 100859- (2022)
Purpose: Hippocampal volume (HV) is an established predicting factor for neurocognitive function (NCF) in neurodegenerative disease. Whether the same phenomenon exists with hippocampal-avoidant whole brain radiation therapy is not known; therefore, w
Externí odkaz:
https://doaj.org/article/1121ee18ee694870924f5da0d3619b23
Autor:
J. John Lucido, PhD, Trey C. Mullikin, MD, Feven Abraha, BS, W. Scott Harmsen, MS, Birjoo D. Vaishnav, PhD, Debra H. Brinkmann, PhD, Roman O. Kowalchuk, MD, Joseph T. Marion, MD, Benjamin A. Johnson-Tesch, MD, Omar El Sherif, PhD, Paul D. Brown, MD, Peter S. Rose, MD, Dawn Owen, MD, PhD, Jonathan M. Morris, MD, Mark R. Waddle, MD, Brittany L. Siontis, MD, Bradley J. Stish, MD, PhD, Deanna H. Pafundi, PhD, Nadia N. Laack, MD, Kenneth R. Olivier, MD, Sean S. Park, MD, PhD, Kenneth W. Merrell, MD
Publikováno v:
Advances in Radiation Oncology, Vol 7, Iss 6, Pp 101047- (2022)
Purpose: This study reports on the risk of radiation-induced myelitis (RM) of the spinal cord from a large single-institutional experience with 1 to 5 fraction stereotactic body radiation therapy (SBRT) to the spine. Methods and Materials: A retrospe
Externí odkaz:
https://doaj.org/article/38944510161c4d8c897a8c02856135e9
Autor:
Eric J. Lehrer, Roman O. Kowalchuk, Henry Ruiz-Garcia, Kenneth W. Merrell, Paul D. Brown, Joshua D. Palmer, Stuart H. Burri, Jason P. Sheehan, Alfredo Quninoes-Hinojosa, Daniel M. Trifiletti
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
Stereotactic radiosurgery (SRS) is the delivery of a high dose ionizing radiation in a highly conformal manner, which allows for significant sparing of nearby healthy tissues. It is typically delivered in 1–5 sessions and has demonstrated safety an
Externí odkaz:
https://doaj.org/article/80ef3e1120074cfbae8b42bf888f61ad