Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Paul D. Baum"'
Autor:
Jennifer J. Young, Rebecca Hoh, Qianjun Zhang, D K Schmidt, Jeffrey N. Martin, Joseph M. McCune, Steven G. Deeks, Michael P. Busch, Paul D. Baum
Publikováno v:
Blood. 119:3469-3477
HIV infection results in a decrease in circulating CD4+ T-cell and naive T-cell numbers. If such losses were associated with an erosion of T-cell receptor (TCR) repertoire diversity in the peripheral T-cell pool, this might exacerbate the state of pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbe1f7c138f2a9f9a15153a7f652062
https://doi.org/10.1182/blood-2011-11-395384
https://doi.org/10.1182/blood-2011-11-395384
Publikováno v:
Analytical Biochemistry. 411:106-115
Methods to measure the sequence diversity of polymerase chain reaction (PCR)-amplified DNA lack standards for use as assay calibrators and controls. Here we present a general and economical method for developing customizable DNA standards of known se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b49b7bf649ee59caa405e05f6ed0a076
https://doi.org/10.1016/j.ab.2010.11.035
https://doi.org/10.1016/j.ab.2010.11.035
Autor:
Joseph M. McCune, Paul D. Baum
Publikováno v:
Nature Methods. 3:895-901
Many studies require the measurement of nucleic acid sequence diversity. Here we describe a method, called AmpliCot, that measures the sequence diversity of PCR products on the basis of DNA hybridization kinetics, thereby avoiding the time, expense a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22edfdecdc9d1a1e494b0a7fb4c536a
https://doi.org/10.1038/nmeth949
https://doi.org/10.1038/nmeth949
Publikováno v:
Development. 130:6507-6518
Achaete-Scute basic helix-loop-helix (bHLH) proteins promote neurogenesis during metazoan development. In this study, we characterize a C. elegans Achaete-Scute homolog, HLH-14. We find that a number of neuroblasts express HLH-14 in the C. elegans em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df996947e168d2d00b4ae2f56c015869
https://doi.org/10.1242/dev.00894
https://doi.org/10.1242/dev.00894
Publikováno v:
Genes & Development. 13:472-483
The Caenorhabditis elegans HSN motor neurons permit genetic analysis of neuronal development at single-cell resolution. The egl-5 Hox gene, which patterns the posterior of the embryo, is required for both early (embryonic) and late (larval) developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4359b2e64fdd56e79218ba8c38286d
https://doi.org/10.1101/gad.13.4.472
https://doi.org/10.1101/gad.13.4.472
Autor:
Gian Garriga, Paul D. Baum
Publikováno v:
Neuron. 19:51-62
Integrins are heterodimeric cell surface receptors implicated in cell adhesion and signaling. Our analysis of C. elegans ina-1 alpha integrin mutants provides the first genetic evidence that migrating neurons require integrins. Mosaic analysis and ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f9bb51b687c4123a329590b5520f8d
https://doi.org/10.1016/s0896-6273(00)80347-5
https://doi.org/10.1016/s0896-6273(00)80347-5
Publikováno v:
European journal of immunology. 42(11)
Next generation sequencing technologies are revolutionizing the study of immune repertoires. These methods provide a previously unimaginable amount of sequence data, unfortunately accompanied by numerous challenges associated with error correction an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b9a7cebc5992304efe59f8284a34ea
https://pubmed.ncbi.nlm.nih.gov/22806588
https://pubmed.ncbi.nlm.nih.gov/22806588
Publikováno v:
AIDS (London, England). 25(18)
To provide a molecular mechanism that explains the association of the antiretroviral guanosine analogue, abacavir, with an increased risk of myocardial infarction.Drug effects were studied with biochemical and cellular assays.Human platelets were inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198aa7dad960e68e54b3d9c1f02f6806
https://pubmed.ncbi.nlm.nih.gov/21941165
https://pubmed.ncbi.nlm.nih.gov/21941165
Publikováno v:
Journal of immunological methods. 368(1-2)
T cell receptor (TCR) diversity is critical for adaptive immunity. Existing methods for measuring such diversity are qualitative, expensive, and/or of uncertain accuracy. Here, we describe a method and associated reagents for estimating the absolute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ee6df46bfa93a2570dfecbb3ba9b88
https://pubmed.ncbi.nlm.nih.gov/21385585
https://pubmed.ncbi.nlm.nih.gov/21385585
Autor:
Shigeki Watanabe, Kim Schuske, Paul D. Baum, Gian Garriga, Qiang Liu, Erik M. Jorgensen, Mingyu Gu
Publikováno v:
The Journal of Cell Biology
Synaptic vesicles must be recycled to sustain neurotransmission, in large part via clathrin-mediated endocytosis. Clathrin is recruited to endocytic sites on the plasma membrane by the AP2 adaptor complex. The medium subunit (μ2) of AP2 binds to car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13686d0b4e734063bda8f3f5675b726
https://pubmed.ncbi.nlm.nih.gov/19047463
https://pubmed.ncbi.nlm.nih.gov/19047463