Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Paul D Kassner"'
Autor:
Qingfeng Zhu, Robert Anders, Damian Trujillo, Dirk G Brockstedt, Michael Chisamore, Juraj Adamik, Paul D Kassner, William Ho, Rakesh Kumar Goyal, Adam Grant, Shoji Ikeda, Marvin Au, Denise Nagata, Eugene Lurie, Mohsen Sabouri Ghomi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e2bf8d74d1f9425eab362253a82843ff
Autor:
Jameel Muzaffar, Tae Min Kim, Julie Brahmer, Dirk G Brockstedt, Chia-Chi Lin, Michael Chisamore, Ki Hyeong Lee, Paul D Kassner, Nuttapong Ngamphaiboon, William Ho, Nicole Nasrah, Pratibha Desai, Yin-Hsun Feng, Shang-Yin Wu, Rakesh Kumar Goyal
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/bd8985e88135407b9ef78e59280fb9c0
Autor:
Aparna Jorapur, Lisa A Marshall, Scott Jacobson, Mengshu Xu, Sachie Marubayashi, Mikhail Zibinsky, Dennis X Hu, Omar Robles, Jeffrey J Jackson, Valentin Baloche, Pierre Busson, David Wustrow, Dirk G Brockstedt, Oezcan Talay, Paul D Kassner, Gene Cutler
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010200 (2022)
The Epstein-Barr Virus (EBV) is involved in the etiology of multiple hematologic and epithelial human cancers. EBV+ tumors employ multiple immune escape mechanisms, including the recruitment of immunosuppressive regulatory T cells (Treg). Here, we sh
Externí odkaz:
https://doaj.org/article/4d16e0321b6e41c7ae448e91efe27eef
Autor:
Brian Wong, Dirk G Brockstedt, Lisa A Marshall, Sachie Marubayashi, Aparna Jorapur, Scott Jacobson, Mikhail Zibinsky, Omar Robles, Dennis Xiaozhou Hu, Jeffrey J Jackson, Deepa Pookot, Jerick Sanchez, Martin Brovarney, Angela Wadsworth, David Chian, David Wustrow, Paul D Kassner, Gene Cutler, Oezcan Talay
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Checkpoint inhibitors (CPIs) such as anti-PD(L)-1 and anti-CTLA-4 antibodies have resulted in unprecedented rates of antitumor responses and extension of survival of patients with a variety of cancers. But some patients fail to respond or
Externí odkaz:
https://doaj.org/article/3beb97b17518498284642adadb08fbeb
Autor:
Olivier Nolan-Stevaux, Donato Tedesco, Seamus Ragan, Mikhail Makhanov, Alex Chenchik, Astrid Ruefli-Brasse, Kim Quon, Paul D Kassner
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67316 (2013)
Advances in the fields of cancer initiating cells and high-throughput in vivo shRNA screens have highlighted a need to observe the growth of tumor cells in cancer models at the clonal level. While in vivo cancer cell growth heterogeneity in xenograft
Externí odkaz:
https://doaj.org/article/d543f9d0580a4e009f73c664a33a19f2
Autor:
Karen Rex, Shawn Jeffries, Matthew L Brown, Timothy Carlson, Angela Coxon, Flordeliza Fajardo, Brendon Frank, Darin Gustin, Alexander Kamb, Paul D Kassner, Shyun Li, Yihong Li, Kurt Morgenstern, Matthew Plant, Kim Quon, Astrid Ruefli-Brasse, Joanna Schmidt, Elissa Swearingen, Nigel Walker, Zhulun Wang, J E Vivienne Watson, Dineli Wickramasinghe, Mariwil Wong, Guifen Xu, Holger Wesche
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68328 (2013)
Sphingosine kinases (SPHKs) are enzymes that phosphorylate the lipid sphingosine, leading to the formation of sphingosine-1-phosphate (S1P). In addition to the well established role of extracellular S1P as a mitogen and potent chemoattractant, SPHK a
Externí odkaz:
https://doaj.org/article/dfda1f39979a456d9edd17f32579cba1
Autor:
Jeffrey J. Jackson, Grant M. Shibuya, Buvana Ravishankar, Lavanya Adusumilli, Delia Bradford, Dirk G. Brockstedt, Cyril Bucher, Minna Bui, Cynthia Cho, Christoph Colas, Gene Cutler, Adrian Dukes, Xinping Han, Dennis X. Hu, Scott Jacobson, Paul D. Kassner, George E. Katibah, Michelle Yoo Min Ko, Urvi Kolhatkar, Paul R. Leger, Anqi Ma, Lisa Marshall, Jack Maung, Andrew A. Ng, Akinori Okano, Deepa Pookot, Daniel Poon, Chandru Ramana, Maureen K. Reilly, Omar Robles, Jacob B. Schwarz, Anton A. Shakhmin, Hunter P. Shunatona, Raashi Sreenivasan, Parcharee Tivitmahaisoon, Mengshu Xu, Thant Zaw, David J. Wustrow, Mikhail Zibinsky
Publikováno v:
Journal of Medicinal Chemistry. 65:12895-12924
General control nonderepressible 2 (GCN2) protein kinase is a cellular stress sensor within the tumor microenvironment (TME), whose signaling cascade has been proposed to contribute to immune escape in tumors. Herein, we report the discovery of cell-
Autor:
Paul D. Kassner, Dirk G. Brockstedt, David Wustrow, Jacob Schwarz, Christophe Colas, Jack Maung, Akinori Okano, Xinping Han, Nathan Kozon, Delia Bradford, Lisa A. Marshall, Silpa Suthram, Kyle Young, Betty Abraham, Deepa Pookot, Niket Shah, Jerick Sanchez, Steve T. Wong, Scott Jacobson, Cynthia Cho, Payal Rana, Berenger Biannic, Dennis X. Hu, Paul R. Leger, Gene Cutler, Michael T. Sun, Yamini M. Ohol
Genes whose expression is significantly altered upon USP7 inhibitor treatment of H526 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f989ee2cc8256a47675f17613ed482
https://doi.org/10.1158/1535-7163.22518810
https://doi.org/10.1158/1535-7163.22518810
Autor:
Paul D. Kassner, Dirk G. Brockstedt, David Wustrow, Jacob Schwarz, Christophe Colas, Jack Maung, Akinori Okano, Xinping Han, Nathan Kozon, Delia Bradford, Lisa A. Marshall, Silpa Suthram, Kyle Young, Betty Abraham, Deepa Pookot, Niket Shah, Jerick Sanchez, Steve T. Wong, Scott Jacobson, Cynthia Cho, Payal Rana, Berenger Biannic, Dennis X. Hu, Paul R. Leger, Gene Cutler, Michael T. Sun, Yamini M. Ohol
The deubiquitinase USP7 regulates the levels of multiple proteins with roles in cancer progression and immune response. Thus, USP7 inhibition may decrease oncogene function, increase tumor suppressor function, and sensitize tumors to DNA-damaging age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2553fdd80c98dcbf6dde06a2115d9b1f
https://doi.org/10.1158/1535-7163.c.6542127.v1
https://doi.org/10.1158/1535-7163.c.6542127.v1
Autor:
Paul D. Kassner, Dirk G. Brockstedt, David Wustrow, Jacob Schwarz, Christophe Colas, Jack Maung, Akinori Okano, Xinping Han, Nathan Kozon, Delia Bradford, Lisa A. Marshall, Silpa Suthram, Kyle Young, Betty Abraham, Deepa Pookot, Niket Shah, Jerick Sanchez, Steve T. Wong, Scott Jacobson, Cynthia Cho, Payal Rana, Berenger Biannic, Dennis X. Hu, Paul R. Leger, Gene Cutler, Michael T. Sun, Yamini M. Ohol
Supplementary Figures S1-S6 and legends, and Tables S1, S2, S5, S6, S7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608a87c8b9624888e8b1c3a5ac3f572b
https://doi.org/10.1158/1535-7163.22518816.v1
https://doi.org/10.1158/1535-7163.22518816.v1