Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Paul D Hanavan"'
Autor:
Lee Tran, Paul D Hanavan, Latoya E Campbell, Elena De Filippis, Douglas F Lake, Dawn K Coletta, Lori R Roust, Lawrence J Mandarino, Chad C Carroll, Christos S Katsanos
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160057 (2016)
Our previous studies show reduced abundance of the β-subunit of mitochondrial H+-ATP synthase (β-F1-ATPase) in skeletal muscle of obese individuals. The β-F1-ATPase forms the catalytic core of the ATP synthase, and it is critical for ATP productio
Externí odkaz:
https://doaj.org/article/9ef4ec0d8079412183dd26eb9810abd6
Autor:
Douglas F. Lake, Thai H. Ho, Huijun Luo, Shamit K. Dutta, Krishnendu Pal, Debabrata Mukhopadhyay, John A. Copland, Erik P. Castle, Thomas R. Caulfield, Alysia Polito, Joachim L. Petit, Nathalie Meurice, Andrey Bobkov, Eduard Sergienko, Douglas O. Faigel, Paul D. Hanavan, Amber L. Fifield
*Supplementary Figure 1 shows the chemical structure of SBI-183. *Supplementary Figure 2 displays the verification of shRNA KD of QSOX1 by qRT-PCR. *Supplementary Table 1 shows the results from our docking protocols. *Supplementary Figure 3 displays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0812ae1752e6a7688f19f5d7d993e2a7
https://doi.org/10.1158/1535-7163.22507063
https://doi.org/10.1158/1535-7163.22507063
Autor:
Douglas F. Lake, Thai H. Ho, Huijun Luo, Shamit K. Dutta, Krishnendu Pal, Debabrata Mukhopadhyay, John A. Copland, Erik P. Castle, Thomas R. Caulfield, Alysia Polito, Joachim L. Petit, Nathalie Meurice, Andrey Bobkov, Eduard Sergienko, Douglas O. Faigel, Paul D. Hanavan, Amber L. Fifield
Quiescin sulfhydryl oxidase 1 (QSOX1) is an enzyme overexpressed by many different tumor types. QSOX1 catalyzes the formation of disulfide bonds in proteins. Because short hairpin knockdowns (KD) of QSOX1 have been shown to suppress tumor growth and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cfd2637f0dcaafeb2948040e6fbd1e9
https://doi.org/10.1158/1535-7163.c.6538567.v1
https://doi.org/10.1158/1535-7163.c.6538567.v1
Autor:
Nathalie Meurice, Debabrata Mukhopadhyay, Krishnendu Pal, Alysia N. Polito, Thai H. Ho, Paul D. Hanavan, Andrey A. Bobkov, Huijun Luo, Douglas O. Faigel, Shamit K. Dutta, Eduard Sergienko, Amber Fifield, John A. Copland, Erik P. Castle, Thomas R. Caulfield, Joachim L. Petit, Douglas F. Lake
Publikováno v:
Molecular Cancer Therapeutics. 19:112-122
Quiescin sulfhydryl oxidase 1 (QSOX1) is an enzyme overexpressed by many different tumor types. QSOX1 catalyzes the formation of disulfide bonds in proteins. Because short hairpin knockdowns (KD) of QSOX1 have been shown to suppress tumor growth and
Autor:
Paul D. Hanavan, Huijun Luo, Yvette W. Ruiz, Katon A. Kras, Xianfeng Chen, Thai H. Ho, Jingping Liu, Daniel R. O'Brien, Douglas F. Lake, Keith D. Robertson, Haiwei Gu, Erik P. Castle
SETD2, a histone H3 lysine trimethyltransferase, is frequently inactivated and associated with recurrence of clear cell renal cell carcinoma (ccRCC). However, the impact of SETD2 loss on metabolic alterations in ccRCC is still unclear. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5c1fbd38d66b0f97a4516ea00a838c
https://europepmc.org/articles/PMC6465098/
https://europepmc.org/articles/PMC6465098/
Autor:
Chen Ting Ma, Douglas F. Lake, Nathalie Meurice, Benjamin A. Katchman, Thai H. Ho, Douglas O. Faigel, Eduard Sergienko, Paul D. Hanavan, Chad R. Borges, Joachim L. Petit
Publikováno v:
Oncotarget
// Paul D. Hanavan 1 , Chad R. Borges 2 , Benjamin A. Katchman 2 , Douglas O. Faigel 3 , Thai H. Ho 3 , Chen-Ting Ma 4 , Eduard A. Sergienko 4 , Nathalie Meurice 3 , Joachim L. Petit 3 , Douglas F. Lake 1 1 School of Life Sciences, Mayo Clinic Collab
Autor:
Paul D. Hanavan, Nathalie Meurice, Douglas O. Faigel, Amber Fifield, Thai H. Ho, Douglas F. Lake, Eduard Sergienko
Publikováno v:
Gastroenterology. 152:S276
Autor:
Ernest F. Terwilliger, J. Bryce Ortiz, Paul D. Hanavan, Cheryl D. Conrad, Ann N. Hoffman, Coy M. Mathewson
Publikováno v:
The European journal of neuroscience. 40(9)
Chronic restraint stress impairs hippocampal-mediated spatial learning and memory, which improves following a post-stress recovery period. Here, we investigated whether brain-derived neurotrophic factor (BDNF), a protein important for hippocampal fun
Autor:
Douglas F. Lake, Daruka Mahadevan, Cheryl E. Myers, A. Jamal Nadeem, Laurence Cooke, Paul D. Hanavan, Zachary R. Laughrey, Kwasi Antwi, Adrienne C. Scheck
Publikováno v:
Cancer immunology, immunotherapy : CII. 60(9)
Genetic instability of tumor cells can result in translation of proteins that are out of frame, resulting in expression of neopeptides. These neopeptides are not self-proteins and therefore should be immunogenic. By eluting peptides from human gliobl
Autor:
Kwasi Antwi, Paul D. Hanavan, Cheryl E. Myers, Eric J. Thompson, Yvette W. Ruiz, Douglas F. Lake
Publikováno v:
Molecular immunology. 46(15)
Peptides bound to cell surface MHC class I molecules allow the immune system to recognize intracellular pathogens and tumor-derived peptides. Our goal was to learn what the immune system "sees" on the surfaces of tumor cells by acid-eluting peptides