Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Paul D Coleman"'
Autor:
Diego Mastroeni, Shobana Sekar, Jennifer Nolz, Elaine Delvaux, Katie Lunnon, Jonathan Mill, Winnie S Liang, Paul D Coleman
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191382 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0177814.].
Externí odkaz:
https://doaj.org/article/ef111e1b74364a4b8b41c00f6cf51a26
Autor:
Diego Mastroeni, Shobana Sekar, Jennifer Nolz, Elaine Delvaux, Katie Lunnon, Jonathan Mill, Winnie S Liang, Paul D Coleman
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0177814 (2017)
Recent epigenetic association studies have identified a new gene, ANK1, in the pathogenesis of Alzheimer's disease (AD). Although strong associations were observed, brain homogenates were used to generate the data, introducing complications because o
Externí odkaz:
https://doaj.org/article/f4fbb189ce6a48aa8835a0d7476623c4
Autor:
Pamela J Yao, Min Zhu, Eunice I Pyun, Andrew I Brooks, Stavros Therianos, Victoria E Meyers, Paul D Coleman
Publikováno v:
Neurobiology of Disease, Vol 12, Iss 2, Pp 97-109 (2003)
Loss of synapses correlates with cognitive decline in Alzheimer’s disease (AD). However, molecular mechanisms underlying the synaptic dysfunction and loss are not well understood. In this study, microarray analysis of brain tissues from five AD cas
Externí odkaz:
https://doaj.org/article/c7fb25f97f7146a490c7bfe08df24bdd
Autor:
Diego Mastroeni, Leonidas Chouliaras, Andrew Grover, Winnie S Liang, Kevin Hauns, Joseph Rogers, Paul D Coleman
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53349 (2013)
Transcription of DNA is essential for cell maintenance and survival; inappropriate localization of proteins that are involved in transcription would be catastrophic. In Alzheimer's disease brains, and in vitro studies, we have found qualitative and q
Externí odkaz:
https://doaj.org/article/37f7bb5c09c84f67bb6ef9acc47eeb2c
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6617 (2009)
DNA methylation is capable of modulating coordinate expression of large numbers of genes across many different pathways, and may therefore warrant investigation for their potential role between genes and disease phenotype. In a rare set of monozygoti
Externí odkaz:
https://doaj.org/article/2fbb561badee4b249b3a384c77a4a7ee
Autor:
Ignazio S. Piras, Danielle Brokaw, Yinfei Kong, Daniel J. Weisenberger, Jonida Krate, Elaine Delvaux, Swapna Mahurkar, Adam Blattler, Kimberly D. Siegmund, Lucia Sue, Geidy E. Serrano, Thomas G. Beach, Peter W. Laird, Matthew J. Huentelman, Paul D. Coleman
Publikováno v:
Cellular and Molecular Neurobiology.
Alzheimer’s disease is a neurodegenerative disorder clinically defined by gradual cognitive impairment and alteration in executive function. We conducted an epigenome-wide association study (EWAS) of a clinically and neuropathologically characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50e35b507d0e2c41389ff8e8614e0686
https://doi.org/10.1007/s10571-022-01307-3
https://doi.org/10.1007/s10571-022-01307-3
Publikováno v:
Biomolecules; Volume 12; Issue 11; Pages: 1592
The clinical diagnosis of neurodegenerative diseases is notoriously inaccurate and current methods are often expensive, time-consuming, or invasive. Simple inexpensive and noninvasive methods of diagnosis could provide valuable support for clinicians
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ef09420cf638bd86f1db6d7da9c09e
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES.
Dysfunctional processes in Alzheimer's disease and other neurodegenerative diseases lead to neural degeneration in the central and peripheral nervous system. Research demonstrates that neurodegeneration of any kind is a systemic disease that may even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658186223bf352a7220ba68d7c3bafa5
https://pubmed.ncbi.nlm.nih.gov/36541444
https://pubmed.ncbi.nlm.nih.gov/36541444
Autor:
Ignazio S, Piras, Danielle, Brokaw, Yinfei, Kong, Daniel J, Weisenberger, Jonida, Krate, Elaine, Delvaux, Swapna, Mahurkar, Adam, Blattler, Kimberly D, Siegmund, Lucia, Sue, Geidy E, Serrano, Thomas G, Beach, Peter W, Laird, Matthew J, Huentelman, Paul D, Coleman
Publikováno v:
Cellular and molecular neurobiology.
Alzheimer's disease is a neurodegenerative disorder clinically defined by gradual cognitive impairment and alteration in executive function. We conducted an epigenome-wide association study (EWAS) of a clinically and neuropathologically characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53beac519c9a4311156fb5bcd889135b
https://pubmed.ncbi.nlm.nih.gov/36596913
https://pubmed.ncbi.nlm.nih.gov/36596913
Autor:
Danielle Brokaw, Thomas G. Beach, Geidy E. Serrano, Diego Mastroeni, Matthew J. Huentelman, Ignazio S. Piras, Jennifer Nolz, Paul D. Coleman, Daniel J. Weisenberger, Elaine Delvaux
Publikováno v:
Neurobiol Aging
Whether a cell lives or dies is controlled by an array of intercepting and dynamic molecular pathways. Although there is evidence of neuronal loss in Alzheimer’s disease (AD) and multiple programmed cell death (PCD) pathways have been implicated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042acdd8c17e8691a2f711ae30d23960
https://doi.org/10.1016/j.neurobiolaging.2020.06.022
https://doi.org/10.1016/j.neurobiolaging.2020.06.022