Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Paul D, Metzak"'
Autor:
Paul D. Metzak, Mohammed K. Shakeel, Xiangyu Long, Mike Lasby, Roberto Souza, Signe Bray, Benjamin I. Goldstein, Glenda MacQueen, JianLi Wang, Sidney H. Kennedy, Jean Addington, Catherine Lebel
Publikováno v:
BMC Psychiatry, Vol 22, Iss 1, Pp 1-18 (2022)
Abstract Background Identifying early biomarkers of serious mental illness (SMI)—such as changes in brain structure and function—can aid in early diagnosis and treatment. Whole brain structural and functional connectomes were investigated in yout
Externí odkaz:
https://doaj.org/article/d9cc2773a0414834a2a3b4b30c4fa4a9
Autor:
Nikita, Nogovitsyn, Paul D, Metzak, Raphael F, Casseb, Roberto, Souza, Jacqueline K, Harris, Lionel M, Prati, Mojdeh, Zamyadi, Signe L, Bray, Catherine, Lebel, Stefanie, Hassel, Stephen, Strother, Benjamin I, Goldstein, JianLi, Wang, Sidney H, Kennedy, Glenda M, MacQueen, Jean, Addington
Publikováno v:
Schizophrenia Research. 240:220-227
Youth at clinical high risk (CHR) for psychosis can present not only with characteristic attenuated psychotic symptoms but also may have other comorbid conditions, including anxiety and depression. These undifferentiated mood symptoms can overlap wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677c2ebaa531a1d99b1e1a8005a0d846
https://doi.org/10.1016/j.schres.2021.12.041
https://doi.org/10.1016/j.schres.2021.12.041
Autor:
Thea J Placsko, Monica Chu, Jean Addington, Kali Brummitt, Paul D. Metzak, Megan S. Farris, Dominique Bonneville, Amy Braun
Publikováno v:
Schizophr Res
Impairments in social functioning are a core impairment in psychosis and are associated with poor outcomes. These deficits are found in those at clinical high-risk (CHR) for psychosis, and can persist even in the absence of transition. However, the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea982c5f2db90203d92800eb476033b
https://doi.org/10.1016/j.schres.2021.04.013
https://doi.org/10.1016/j.schres.2021.04.013
Autor:
Signe Bray, Benjamin I. Goldstein, Jean Addington, Bradley J. MacIntosh, Catherine Lebel, Paul D. Metzak, Stefanie Hassel, JianLi Wang, Sidney H. Kennedy, Glenda MacQueen
Publikováno v:
Early Intervention in Psychiatry. 15:1276-1291
Background In their early stages, serious mental illnesses (SMIs) are often indistinguishable from one another, suggesting that studying alterations in brain activity in a transdiagnostic fashion could help to understand the neurophysiological origin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b011c56845890258186f472fe0b5b1
https://doi.org/10.1111/eip.13078
https://doi.org/10.1111/eip.13078
Publikováno v:
Neuroscience & Biobehavioral Reviews. 118:367-383
The negative symptoms of schizophrenia are linked to poorer functional outcomes and decreases in quality of life, and are often the first to develop in individuals who are at clinical high risk (CHR) for psychosis. However, the accompanying neurobiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ce56336784fd59b8548ac4cd80eac3
https://doi.org/10.1016/j.neubiorev.2020.07.041
https://doi.org/10.1016/j.neubiorev.2020.07.041
Autor:
Paul D. Metzak, Mohammed K. Shakeel, Xiangyu Long, Mike Lasby, Roberto Souza, Signe Bray, Benjamin I. Goldstein, Glenda MacQueen, JianLi Wang, Sidney H. Kennedy, Jean Addington, Catherine Lebel
Publikováno v:
BMC psychiatry. 22(1)
Background Identifying early biomarkers of serious mental illness (SMI)—such as changes in brain structure and function—can aid in early diagnosis and treatment. Whole brain structural and functional connectomes were investigated in youth at risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e18abaeca1dcbe7b0fd8d24c0fb59f
https://pubmed.ncbi.nlm.nih.gov/36109720
https://pubmed.ncbi.nlm.nih.gov/36109720
Autor:
Roumen Milev, Paul D. Metzak, Claudio N. Soares, Stephen R. Arnott, Jacqueline K. Harris, Nikita Nogovitsyn, Roberto Souza, Sagar V. Parikh, Mojdeh Zamyadi, Sidney H. Kennedy, Geoffrey B. Hall, Meghan Muller, Kate L. Harkness, Glenda MacQueen, Jonathan Downar, Stefanie Hassel, Stephen C. Strother, Benicio N. Frey, Susan Rotzinger, Raymond W. Lam, Zahinoor Ismail, Jean Addington, Andrew D. Davis
Publikováno v:
Neuropsychopharmacology
Finding a clinically useful neuroimaging biomarker that can predict treatment response in patients with major depressive disorder (MDD) is challenging, in part because of poor reproducibility and generalizability of findings across studies. Previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96bcef633af8c78b1cc7dfe199f1ffad
https://doi.org/10.1038/s41386-019-0542-1
https://doi.org/10.1038/s41386-019-0542-1
Autor:
Benjamin I. Goldstein, Roberto Souza, Kate L. Harkness, Roumen Milev, Amelia Srajer, Signe Bray, Raymond W. Lam, Jacqueline K. Harris, Nikita Nogovitsyn, Meghan Muller, Jean Addington, Catherine Lebel, Glenda MacQueen, Stefanie Hassel, Benicio N. Frey, Andrew D. Davis, Zahinoor Ismail, Stephen R. Arnott, Susan Rotzinger, Stephen C. Strother, Mojdeh Zamyadi, Paul D. Metzak, Geoffrey B. Hall, Sidney H. Kennedy
Publikováno v:
NeuroImage. 197:589-597
Subtle changes in hippocampal volumes may occur during both physiological and pathophysiological processes in the human brain. Assessing hippocampal volumes manually is a time-consuming procedure, however, creating a need for automated segmentation m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498b98f4f383956c6e30230077bc6843
https://doi.org/10.1016/j.neuroimage.2019.05.017
https://doi.org/10.1016/j.neuroimage.2019.05.017
Publikováno v:
Psychiatry research. Neuroimaging. 305
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d87ef97070f751761d66d0a9b2dd8a7
https://pubmed.ncbi.nlm.nih.gov/33035755
https://pubmed.ncbi.nlm.nih.gov/33035755
Publikováno v:
NPJ Schizophrenia
npj Schizophrenia, Vol 6, Iss 1, Pp 1-7 (2020)
npj Schizophrenia, Vol 6, Iss 1, Pp 1-7 (2020)
Over the past 20 years there has been a great deal of research into those considered to be at risk for developing psychosis. Much has been learned and studies have been encouraging. The aim of this paper is to offer an update of the current status of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cfecd6824710de993508ce819e133de
https://pubmed.ncbi.nlm.nih.gov/33020486
https://pubmed.ncbi.nlm.nih.gov/33020486